PASK (PAS domain containing serine/threonine kinase)

Gene: PASK (PAS domain containing serine/threonine kinase) Sus scrofa

Analyze

Symbol:

PASK (Ensembl: MTERF4)

Name:

PAS domain containing serine/threonine kinase (Ensembl:mitochondrial transcription termination factor 4)

RGD ID:

14013541

Description:

ENCODES a protein that exhibits ATP binding (inferred); double-stranded DNA binding (inferred); nucleotide binding (inferred); INVOLVED IN camera-type eye development (ortholog); heart development (ortholog); mitochondrial transcription (ortholog); ASSOCIATED WITH Bethlem Myopathy 1A (ortholog); chromosome 2q37 deletion syndrome (ortholog); D-2-hydroxyglutaric aciduria 1 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrial large ribosomal subunit (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

mitochondrial transcription termination factor 4; MTERF domain containing 2; MTERF4; MTERFD2; transcription termination factor 4, mitochondrial

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	139,881,222 - 139,887,032 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	139,881,217 - 139,887,505 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	154,997,365 - 155,003,731 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bethlem Myopathy 1A (ISO)

chromosome 2q37 deletion syndrome (ISO)

D-2-hydroxyglutaric aciduria 1 (ISO)

genetic disease (ISO)

hereditary spastic paraplegia 30 (ISO)

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

camera-type eye development (IEA,ISO)

energy homeostasis (IEA)

heart development (IEA,ISO)

intracellular signal transduction (IBA,IEA)

mitochondrial ribosome assembly (IEA)

mitochondrial transcription (IEA,ISO)

negative regulation of glycogen biosynthetic process (IBA,IEA)

protein targeting to mitochondrion (IEA,ISO)

regulation of DNA-templated transcription (IEA)

regulation of glucagon secretion (IEA)

regulation of respiratory gaseous exchange (IEA)

ribosome assembly (IEA,ISO)

Cellular Component

cytoplasm (IBA,IEA)

cytosol (IBA,IEA)

mitochondrial large ribosomal subunit (IEA)

mitochondrion (IEA)

nucleus (IBA,IEA)

Molecular Function

ATP binding (IEA)

double-stranded DNA binding (IEA)

nucleotide binding (IEA)

phosphatidylinositol binding (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein serine/threonine kinase activity (IBA,IEA)

rRNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PASK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	139,881,222 - 139,887,032 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	139,881,217 - 139,887,505 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	154,997,365 - 155,003,731 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MTERF4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	241,042,586 - 241,102,287 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	241,072,169 - 241,102,332 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	242,011,583 - 242,041,702 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	241,675,180 - 241,690,397 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	235,696,211 - 235,711,450 (-)	NCBI		Celera
Cytogenetic Map	2	q37.3	NCBI
HuRef	2	233,782,517 - 233,797,755 (-)	NCBI		HuRef
CHM1_1	2	242,032,564 - 242,047,803 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	241,539,417 - 241,601,395 (-)	NCBI		T2T-CHM13v2.0

Mterf4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	93,228,927 - 93,233,601 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	93,226,933 - 93,233,637 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	93,301,205 - 93,305,879 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	93,299,211 - 93,305,915 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	95,195,788 - 95,202,447 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	95,129,617 - 95,136,276 (-)	NCBI		MGSCv36	mm8
Celera	1	96,243,881 - 96,250,538 (-)	NCBI		Celera
Cytogenetic Map	1	D	NCBI
cM Map	1	47.24	NCBI

Mterf4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	101,281,560 - 101,286,236 (-)	NCBI		GRCr8
mRatBN7.2	9	93,834,162 - 93,838,838 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	93,834,144 - 93,838,864 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	102,269,722 - 102,274,398 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	107,405,509 - 107,410,186 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	105,761,651 - 105,766,328 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	100,440,482 - 100,445,158 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	100,440,486 - 100,445,158 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	100,096,837 - 100,101,513 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	92,572,064 - 92,576,740 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	91,369,116 - 91,373,792 (-)	NCBI		Celera
Cytogenetic Map	9	q36	NCBI

Mterf4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955542	579,356 - 584,508 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955542	579,183 - 584,617 (+)	NCBI	ChiLan1.0	ChiLan1.0

MTERF4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	143,774,572 - 143,795,662 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	143,789,537 - 143,810,627 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	128,330,967 - 128,362,014 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	247,131,640 - 247,158,239 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	247,128,252 - 247,158,239 (-)	Ensembl	panpan1.1		panPan2

MTERF4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	51,129,186 - 51,144,452 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	51,351,824 - 51,357,081 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	51,333,637 - 51,338,907 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	51,333,638 - 51,338,379 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	51,158,150 - 51,186,619 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	50,920,889 - 50,926,153 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	51,197,133 - 51,202,402 (-)	NCBI		UU_Cfam_GSD_1.0

Mterf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	192,509,991 - 192,514,021 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936745	705,448 - 709,429 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MTERF4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	127,145,903 - 127,152,721 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	127,146,466 - 127,152,655 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	72,230,324 - 72,237,126 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mterf4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624847	5,207,882 - 5,214,156 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624847	5,207,624 - 5,214,218 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in PASK
132 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium
Low	6	2	2	4		11	2	2	2
Below cutoff	4	2	1	1	2	12		1	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003133812	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013982507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013982508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP102549	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01095563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000017835 ⟹ ENSSSCP00000017354

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	139,881,222 - 139,887,032 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000044949 ⟹ ENSSSCP00000034965

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	139,890,178 - 139,917,069 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000101870 ⟹ ENSSSCP00000076410

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	139,883,407 - 139,885,869 (-)	Ensembl

RefSeq Acc Id:

XM_003133812 ⟹ XP_003133860

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	15	139,881,217 - 139,887,105 (-)	NCBI

Sequence:

show sequence

AGCGGCGGACCGGGAGGGCGGAAGGGGCGGGCCCGAGAAGGCCGGCTTCCGGCGCCGGCCCCCT
GCTGCCCCTGCCTCGGCGCTATGGCGGCGCTCGGTCGGCAGGTCTTTCAGTGGCACCGGCTCAC
GCCTGTCACGGGGACCGTCGTTGCTGGACACACTCCTCAGCTTGGAGAGCAGAAGAGGATGGTG
GCTTTTTTGCTGCGTAAACTGACCACGGTCTCTGATGGAGGCGGCCTCGAGGAGCCATCCTTTG
TCGAACCCGGAAAGCGTGTGCAGGAACCAGAGCACAGGACGGGTCTGACTCGGTGCCTCCTTGA
GAAGCAGAGGACTGCCGTGGAGCCGGAGACGGTGGTCCGTTCCCTCCGGGACCTGGGTTTCAGT
GATGTCCACGCTCATGAGTTGCTGCGTCTGCAGCCAGGTACCCGCCCTCAGCAGTTGCTGGACA
TCATTTCAGAATTAATGCTCTTGGGTCTGAATCCAGAACCTGTGTGTGTGGCCTTGAAGAGAAG
CCCTCAACTGTTGGACCTGCCTGTGATGCAGATGAAGAAGCGCTCCAGTTACCTGCGGAAGCTT
GGGCTCGGAGAGGGGAGACTGAAGAGGGTCCTTCAGTGCTGCCCTGAAATTTTCACCATGCGTC
AGCGGGACCTGGAGAGCATCGTCGGGGTTCTCAGGGAGAGGTGCCTTTTCACGGTAAAGCAAGT
AACGGAGGTTTTGCACAGATGCCCCCATGTGCTCCGGGAGGACCCTGCTGAGCTGGAATACAAA
TTCCAGTATGCGTATTTCAGGATGGGGCTCAGGCCCGCGGACGTGGTGAGGACTGACTTCCTGC
AGTACCCCATGGCCAAGATCAAGCAGAGGCACGTGTTCCTGGAGCGCCTGGGCCGCTACCAAAC
CCCCGACAAGAAGGGGCAGACGCAGGTCCCCAACCCTTTGCTCAAGGGCATCCTCAGAGTTTCA
GAAGCTGAGTTTCTGGCCAGGACAGCCTGTGCTTCTGCGGAGGAGTTTGAGGTCTTTAAGAAGC
TCTTGGCTCGGGAGGAAGAGGAGACCGAGGAGCGCGGGGCTGCTGACGACAGTCGGGCGGGGGA
GGAGGGGGAGGAGGACGAGGCGGGGGAGGAGGGGGGGAGGAGGGGCAGCGGGAGCCGTGACGGG
AGGACGGGGGGCCAGGAGCCCAGAGAGACGGAAGCGGAGTTTCATTTTCTCACGGCTTTTGGGA
ACTGCATTTTGGATCTGCTCGGGTTATTTTTTATTCTAGAACTGGTCTTTGAGGAGTGACTTGC
TGGCCTGCCCATCAAGGATTCAGCATGTCACGGCTGTGGCAGAAAGGGTTCTCTCCCTGGCCTG
GGACCTTCCGCATGCCGCGGGCATGGTTCCCTCAAAAAACCCCAAAAACAAACAAAACTGGCTT
TTTTCTTTATTTTTTGTCTCTTTGTGCCTTTTCTAGGGCCACTCCCGCAGCACATGGAGGTTCC
CAGGCTAGGGGTCGAATTGGAGCTGTAGCCGCTGGCCTCCACCACAGCCACAGCAACACGGGAT
CTGAGCCTCGTCTACAACCTACACCACAGCTCACGGCAGTGCCGGATCCTCAACCCACTGAGCG
AGGCCAGGGATCGAACCCGCAACCTTGTGGTTCCTAGTCGGATTCGTTAACCCCTGAGCCACGA
CGGGAACTCCATAACTGGCCTTTTAATGGAAAGTTTTTAGAAATCACTTGAGAAGTGGACCCAT
CAAACCACAGAGCAGACGGCTCCGTTTGCTCCACTGTCAGGCTCTGCGCAGAGGGCCCTGCTCC
GTCCTGAATAAAAGCTGACGTCGAGCTCCGAACATCGGGGCCCAGCCTCAGCCTTTGGTTTCGC

hide sequence

RefSeq Acc Id:

XM_013982507 ⟹ XP_013837961

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	15	139,881,217 - 139,886,725 (-)	NCBI

Sequence:

show sequence

TGTGCGGGGCCTCGGGATTTGGCCCCGACGTGTCACGCGCTGGCTCGAACCCTTGGGGAATTTT
CAAGTGAAGGCGAATTGTGTTTAGTTGGCGGACAGGCTGACAGTACTCTTTTTGCGGAATGAAT
TTAGGTACATGAGTCTGGAGACTAGCATGAGGTCCAGATGTTTCAGGTGTGGGTACCAGCTCGG
ACCCACAGCAGACACAGAAAGCAGCCTTGGAGCTTCCCTTATGGCACTAAGTGTAGAAACTTGT
GGGCGTGAGGGTGCCATAGGTCCTTTCTCCTGGGGAGCTTTGGCCATGAGGTTTTGTTGTTGTT
GTTGTTGTTTGTTTGTTTTTTTAAAAAGGAGGGCAGACCACTTGTGTCTGCATGAACACACATT
GTCACAAACCTTCTGGATCGCCCATGTGTCCCTTAGAAGCCCACCCATTCGTTCTTCCCATAGA
ACCCTTTCTCCCCCTCCCTCTCCCCTGTTAAGTTAGCCCCTAACTCTAGCATTTAGGGAGCTGC
CTTTTTGTGGGCCACCATTTGCGTACATATGCAACTCTTTTTTCTTACTGTTAATCGGTCAGTT
AAATTTGCATGTTCAGGCACTGAACGGAGGAAGAAAAGAGCCACCCGCAAGGAGACTTCACCGG
TGGCCTTGAAATAGTCCTGCTCCGTCCTTCAGCTAGAGCAGCAGAAGCCGACCGCTAGGCTCTT
GCAAGACTGTTCTCTGGGTCTTTCAGTGGCACCGGCTCACGCCTGTCACGGGGACCGTCGTTGC
TGGACACACTCCTCAGCTTGGAGAGCAGAAGAGGATGGTGGCTTTTTTGCTGCGTAAACTGACC
ACGGTCTCTGATGGAGGCGGCCTCGAGGAGCCATCCTTTGTCGAACCCGGAAAGCGTGTGCAGG
AACCAGAGCACAGGACGGGTCTGACTCGGTGCCTCCTTGAGAAGCAGAGGACTGCCGTGGAGCC
GGAGACGGTGGTCCGTTCCCTCCGGGACCTGGGTTTCAGTGATGTCCACGCTCATGAGTTGCTG
CGTCTGCAGCCAGGTACCCGCCCTCAGCAGTTGCTGGACATCATTTCAGAATTAATGCTCTTGG
GTCTGAATCCAGAACCTGTGTGTGTGGCCTTGAAGAGAAGCCCTCAACTGTTGGACCTGCCTGT
GATGCAGATGAAGAAGCGCTCCAGTTACCTGCGGAAGCTTGGGCTCGGAGAGGGGAGACTGAAG
AGGGTCCTTCAGTGCTGCCCTGAAATTTTCACCATGCGTCAGCGGGACCTGGAGAGCATCGTCG
GGGTTCTCAGGGAGAGGTGCCTTTTCACGGTAAAGCAAGTAACGGAGGTTTTGCACAGATGCCC
CCATGTGCTCCGGGAGGACCCTGCTGAGCTGGAATACAAATTCCAGTATGCGTATTTCAGGATG
GGGCTCAGGCCCGCGGACGTGGTGAGGACTGACTTCCTGCAGTACCCCATGGCCAAGATCAAGC
AGAGGCACGTGTTCCTGGAGCGCCTGGGCCGCTACCAAACCCCCGACAAGAAGGGGCAGACGCA
GGTCCCCAACCCTTTGCTCAAGGGCATCCTCAGAGTTTCAGAAGCTGAGTTTCTGGCCAGGACA
GCCTGTGCTTCTGCGGAGGAGTTTGAGGTCTTTAAGAAGCTCTTGGCTCGGGAGGAAGAGGAGA
CCGAGGAGCGCGGGGCTGCTGACGACAGTCGGGCGGGGGAGGAGGGGGAGGAGGACGAGGCGGG
GGAGGAGGGGGGGAGGAGGGGCAGCGGGAGCCGTGACGGGAGGACGGGGGGCCAGGAGCCCAGA
GAGACGGAAGCGGAGTTTCATTTTCTCACGGCTTTTGGGAACTGCATTTTGGATCTGCTCGGGT
TATTTTTTATTCTAGAACTGGTCTTTGAGGAGTGACTTGCTGGCCTGCCCATCAAGGATTCAGC
ATGTCACGGCTGTGGCAGAAAGGGTTCTCTCCCTGGCCTGGGACCTTCCGCATGCCGCGGGCAT
GGTTCCCTCAAAAAACCCCAAAAACAAACAAAACTGGCTTTTTTCTTTATTTTTTGTCTCTTTG
TGCCTTTTCTAGGGCCACTCCCGCAGCACATGGAGGTTCCCAGGCTAGGGGTCGAATTGGAGCT
GTAGCCGCTGGCCTCCACCACAGCCACAGCAACACGGGATCTGAGCCTCGTCTACAACCTACAC
CACAGCTCACGGCAGTGCCGGATCCTCAACCCACTGAGCGAGGCCAGGGATCGAACCCGCAACC
TTGTGGTTCCTAGTCGGATTCGTTAACCCCTGAGCCACGACGGGAACTCCATAACTGGCCTTTT
AATGGAAAGTTTTTAGAAATCACTTGAGAAGTGGACCCATCAAACCACAGAGCAGACGGCTCCG
TTTGCTCCACTGTCAGGCTCTGCGCAGAGGGCCCTGCTCCGTCCTGAATAAAAGCTGACGTCGA
GCTCCGAACATCGGGGCCCAGCCTCAGCCTTTGGTTTCGC

hide sequence

RefSeq Acc Id:

XM_013982508 ⟹ XP_013837962

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	15	139,881,217 - 139,887,505 (-)	NCBI

Sequence:

show sequence

ACGAAATCTTAACCAACTGCATCTGGGACCGACTCCACCTTCCTCAGGCTGCCAGTCCCAGGGA
ACGGCTCCGGGAGGGACCTCGCTTTCTGGGCTGAAGCTGCTGTGGAATCCGGGCAAGGTCTTTC
AGTGGCACCGGCTCACGCCTGTCACGGGGACCGTCGTTGCTGGACACACTCCTCAGCTTGGAGA
GCAGAAGAGGATGGTGGCTTTTTTGCTGCGTAAACTGACCACGGTCTCTGATGGAGGCGGCCTC
GAGGAGCCATCCTTTGTCGAACCCGGAAAGCGTGTGCAGGAACCAGAGCACAGGACGGGTCTGA
CTCGGTGCCTCCTTGAGAAGCAGAGGACTGCCGTGGAGCCGGAGACGGTGGTCCGTTCCCTCCG
GGACCTGGGTTTCAGTGATGTCCACGCTCATGAGTTGCTGCGTCTGCAGCCAGGTACCCGCCCT
CAGCAGTTGCTGGACATCATTTCAGAATTAATGCTCTTGGGTCTGAATCCAGAACCTGTGTGTG
TGGCCTTGAAGAGAAGCCCTCAACTGTTGGACCTGCCTGTGATGCAGATGAAGAAGCGCTCCAG
TTACCTGCGGAAGCTTGGGCTCGGAGAGGGGAGACTGAAGAGGGTCCTTCAGTGCTGCCCTGAA
ATTTTCACCATGCGTCAGCGGGACCTGGAGAGCATCGTCGGGGTTCTCAGGGAGAGGTGCCTTT
TCACGGTAAAGCAAGTAACGGAGGTTTTGCACAGATGCCCCCATGTGCTCCGGGAGGACCCTGC
TGAGCTGGAATACAAATTCCAGTATGCGTATTTCAGGATGGGGCTCAGGCCCGCGGACGTGGTG
AGGACTGACTTCCTGCAGTACCCCATGGCCAAGATCAAGCAGAGGCACGTGTTCCTGGAGCGCC
TGGGCCGCTACCAAACCCCCGACAAGAAGGGGCAGACGCAGGTCCCCAACCCTTTGCTCAAGGG
CATCCTCAGAGTTTCAGAAGCTGAGTTTCTGGCCAGGACAGCCTGTGCTTCTGCGGAGGAGTTT
GAGGTCTTTAAGAAGCTCTTGGCTCGGGAGGAAGAGGAGACCGAGGAGCGCGGGGCTGCTGACG
ACAGTCGGGCGGGGGAGGAGGGGGAGGAGGACGAGGCGGGGGAGGAGGGGGGGAGGAGGGGCAG
CGGGAGCCGTGACGGGAGGACGGGGGGCCAGGAGCCCAGAGAGACGGAAGCGGAGTTTCATTTT
CTCACGGCTTTTGGGAACTGCATTTTGGATCTGCTCGGGTTATTTTTTATTCTAGAACTGGTCT
TTGAGGAGTGACTTGCTGGCCTGCCCATCAAGGATTCAGCATGTCACGGCTGTGGCAGAAAGGG
TTCTCTCCCTGGCCTGGGACCTTCCGCATGCCGCGGGCATGGTTCCCTCAAAAAACCCCAAAAA
CAAACAAAACTGGCTTTTTTCTTTATTTTTTGTCTCTTTGTGCCTTTTCTAGGGCCACTCCCGC
AGCACATGGAGGTTCCCAGGCTAGGGGTCGAATTGGAGCTGTAGCCGCTGGCCTCCACCACAGC
CACAGCAACACGGGATCTGAGCCTCGTCTACAACCTACACCACAGCTCACGGCAGTGCCGGATC
CTCAACCCACTGAGCGAGGCCAGGGATCGAACCCGCAACCTTGTGGTTCCTAGTCGGATTCGTT
AACCCCTGAGCCACGACGGGAACTCCATAACTGGCCTTTTAATGGAAAGTTTTTAGAAATCACT
TGAGAAGTGGACCCATCAAACCACAGAGCAGACGGCTCCGTTTGCTCCACTGTCAGGCTCTGCG
CAGAGGGCCCTGCTCCGTCCTGAATAAAAGCTGACGTCGAGCTCCGAACATCGGGGCCCAGCCT
CAGCCTTTGGTTTCGC

hide sequence

Protein Sequences


Protein RefSeqs	XP_003133860	(Get FASTA)	NCBI Sequence Viewer
	XP_013837961	(Get FASTA)	NCBI Sequence Viewer
	XP_013837962	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000017354
	ENSSSCP00000017354.5
	ENSSSCP00000034965.3
	ENSSSCP00000076410.1
	ENSSSCP00005014352.1
	ENSSSCP00035041228.1
	ENSSSCP00040039342.1
	ENSSSCP00040039433.1

RefSeq Acc Id:	XP_013837962 ⟸ XM_013982508
- Peptide Label:	isoform X2
- UniProtKB:	A0A8D0IV92 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVAFLLRKLTTVSDGGGLEEPSFVEPGKRVQEPEHRTGLTRCLLEKQRTAVEPETVVRSLRDLG FSDVHAHELLRLQPGTRPQQLLDIISELMLLGLNPEPVCVALKRSPQLLDLPVMQMKKRSSYLR KLGLGEGRLKRVLQCCPEIFTMRQRDLESIVGVLRERCLFTVKQVTEVLHRCPHVLREDPAELE YKFQYAYFRMGLRPADVVRTDFLQYPMAKIKQRHVFLERLGRYQTPDKKGQTQVPNPLLKGILR VSEAEFLARTACASAEEFEVFKKLLAREEEETEERGAADDSRAGEEGEEDEAGEEGGRRGSGSR DGRTGGQEPRETEAEFHFLTAFGNCILDLLGLFFILELVFEE hide sequence

RefSeq Acc Id:	XP_003133860 ⟸ XM_003133812
- Peptide Label:	isoform X1
- UniProtKB:	F1SI05 (UniProtKB/TrEMBL), A0A480VV57 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAALGRQVFQWHRLTPVTGTVVAGHTPQLGEQKRMVAFLLRKLTTVSDGGGLEEPSFVEPGKRV QEPEHRTGLTRCLLEKQRTAVEPETVVRSLRDLGFSDVHAHELLRLQPGTRPQQLLDIISELML LGLNPEPVCVALKRSPQLLDLPVMQMKKRSSYLRKLGLGEGRLKRVLQCCPEIFTMRQRDLESI VGVLRERCLFTVKQVTEVLHRCPHVLREDPAELEYKFQYAYFRMGLRPADVVRTDFLQYPMAKI KQRHVFLERLGRYQTPDKKGQTQVPNPLLKGILRVSEAEFLARTACASAEEFEVFKKLLAREEE ETEERGAADDSRAGEEGEEDEAGEEGGRRGSGSRDGRTGGQEPRETEAEFHFLTAFGNCILDLL GLFFILELVFEE hide sequence

RefSeq Acc Id:	XP_013837961 ⟸ XM_013982507
- Peptide Label:	isoform X2
- UniProtKB:	A0A8D0IV92 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVAFLLRKLTTVSDGGGLEEPSFVEPGKRVQEPEHRTGLTRCLLEKQRTAVEPETVVRSLRDLG FSDVHAHELLRLQPGTRPQQLLDIISELMLLGLNPEPVCVALKRSPQLLDLPVMQMKKRSSYLR KLGLGEGRLKRVLQCCPEIFTMRQRDLESIVGVLRERCLFTVKQVTEVLHRCPHVLREDPAELE YKFQYAYFRMGLRPADVVRTDFLQYPMAKIKQRHVFLERLGRYQTPDKKGQTQVPNPLLKGILR VSEAEFLARTACASAEEFEVFKKLLAREEEETEERGAADDSRAGEEGEEDEAGEEGGRRGSGSR DGRTGGQEPRETEAEFHFLTAFGNCILDLLGLFFILELVFEE hide sequence

RefSeq Acc Id:

ENSSSCP00000076410 ⟸ ENSSSCT00000101870

RefSeq Acc Id:

ENSSSCP00000017354 ⟸ ENSSSCT00000017835

RefSeq Acc Id:

ENSSSCP00000034965 ⟸ ENSSSCT00000044949

Protein Domains

PAS Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000016378	Ensembl, UniProtKB/TrEMBL
	ENSSSCG00000055566	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005015299	UniProtKB/TrEMBL
	ENSSSCG00035072201	UniProtKB/TrEMBL
	ENSSSCG00040065569	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000017835	ENTREZGENE
	ENSSSCT00000017835.5	UniProtKB/TrEMBL
	ENSSSCT00000044949.3	UniProtKB/TrEMBL
	ENSSSCT00000101870.1	UniProtKB/TrEMBL
	ENSSSCT00005023862.1	UniProtKB/TrEMBL
	ENSSSCT00035097689.1	UniProtKB/TrEMBL
	ENSSSCT00040089508.1	UniProtKB/TrEMBL
	ENSSSCT00040089721.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.70.10	UniProtKB/TrEMBL
	PAS domain	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	MTERF	UniProtKB/TrEMBL
	MTERF_sf	UniProtKB/TrEMBL
	PAS	UniProtKB/TrEMBL
	PAS-like_dom_sf	UniProtKB/TrEMBL
	PAS_fold	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
NCBI Gene	MTERF4	ENTREZGENE
PANTHER	MAP/MICROTUBULE AFFINITY-REGULATING KINASE	UniProtKB/TrEMBL
	PAS DOMAIN-CONTAINING SERINE/THREONINE-PROTEIN KINASE	UniProtKB/TrEMBL
	PTHR13068	UniProtKB/TrEMBL
	TRANSCRIPTION TERMINATION FACTOR 4, MITOCHONDRIAL	UniProtKB/TrEMBL
Pfam	mTERF	UniProtKB/TrEMBL
	PAS	UniProtKB/TrEMBL
	PAS_9	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PROSITE	PAS	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	Mterf	UniProtKB/TrEMBL
	PAS	UniProtKB/TrEMBL
	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55785	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
UniProt	A0A286ZU04_PIG	UniProtKB/TrEMBL
	A0A480VV57	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0IV92	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1AYC7_PIG	UniProtKB/TrEMBL
	A0A8D1FPF7_PIG	UniProtKB/TrEMBL
	A0A8D1FS07_PIG	UniProtKB/TrEMBL
	A0A8W4FDM6_PIG	UniProtKB/TrEMBL
	F1SI05	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-07-26	PASK	PAS domain containing serine/threonine kinase	MTERF4	mitochondrial transcription termination factor 4	Symbol and/or name change	19259463	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar