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Gene: RRM1 (ribonucleotide reductase catalytic subunit M1) Sus scrofa

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Symbol:

RRM1

Name:

ribonucleotide reductase catalytic subunit M1

RGD ID:

14013431

Description:

ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); disordered domain specific binding (inferred); INVOLVED IN cell proliferation in forebrain (ortholog); male gonad development (ortholog); pyrimidine nucleobase metabolic process (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH adrenocortical carcinoma (ortholog); Animal Disease Models (ortholog); Autosomal Recessive Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions 6 (ortholog); FOUND IN cell projection (ortholog); neuronal cell body (ortholog); nuclear envelope (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ribonucleoside-diphosphate reductase large subunit; ribonucleotide reductase M1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	6,025,073 - 6,065,143 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	6,026,151 - 6,065,211 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	6,818,979 - 6,880,069 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adrenocortical carcinoma (ISO)

Animal Disease Models (ISO)

Autosomal Recessive Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions 6 (ISO)

delta beta-thalassemia (ISO)

Disease Progression (ISO)

Experimental Liver Neoplasms (ISO)

Experimental Seizures (ISO)

hepatocellular carcinoma (ISO)

lung adenocarcinoma (ISO)

lung non-small cell carcinoma (ISO)

neural tube defect (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

2'-deoxyribonucleotide biosynthetic process (IEA)

cell proliferation in forebrain (ISO)

deoxyribonucleotide biosynthetic process (IBA,IEA)

DNA repair (IEA)

male gonad development (ISO)

mitochondrial DNA replication (IEA)

positive regulation of G0 to G1 transition (IEA)

positive regulation of G1/S transition of mitotic cell cycle (IEA)

positive regulation of G2/M transition of mitotic cell cycle (IEA)

protein heterotetramerization (IEA)

pyrimidine nucleobase metabolic process (ISO)

response to ionizing radiation (ISO)

retina development in camera-type eye (ISO)

ribonucleoside diphosphate metabolic process (IEA)

Cellular Component

cell projection (ISO)

centriolar satellite (IEA)

ciliary basal body (IEA)

cytosol (IEA)

mitochondrion (IEA)

neuronal cell body (ISO)

nuclear envelope (ISO)

ribonucleoside-diphosphate reductase complex (IBA,IEA)

Molecular Function

ATP binding (IBA,IEA)

catalytic activity (IEA)

disordered domain specific binding (IEA)

identical protein binding (IEA)

nucleotide binding (IEA)

oxidoreductase activity (IEA)

protein binding (ISO)

purine nucleotide binding (IEA)

ribonucleoside-diphosphate reductase activity (IEA)

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (IBA,IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

adenine phoshoribosyltransferase deficiency pathway (ISO)

adenosine monophosphate deaminase deficiency pathway (ISO)

adenylosuccinate lyase deficiency pathway (ISO)

AICA-ribosuria pathway (ISO)

azathioprine pharmacodynamics pathway (ISO)

gemcitabine pharmacodynamics pathway (ISO)

gemcitabine pharmacokinetics pathway (ISO)

Kelley-Seegmiller syndrome pathway (ISO)

Lesch-Nyhan syndrome pathway (ISO)

mercaptopurine pharmacodynamics pathway (ISO)

molybdenum cofactor deficiency pathway (ISO)

purine metabolic pathway (ISO)

purine nucleoside phosphorylase deficiency pathway (ISO)

tioguanine pharmacodynamics pathway (ISO)

xanthinuria type I pathway (ISO)

xanthinuria pathway (ISO)

xanthinuria type II pathway (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RRM1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	6,025,073 - 6,065,143 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	6,026,151 - 6,065,211 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	6,818,979 - 6,880,069 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RRM1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	4,094,685 - 4,138,932 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	4,094,707 - 4,138,932 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	4,115,915 - 4,160,162 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	4,072,500 - 4,116,682 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	4,072,586 - 4,116,681	NCBI
Celera	11	4,120,880 - 4,164,701 (+)	NCBI		Celera
Cytogenetic Map	11	p15.4	NCBI
HuRef	11	3,849,345 - 3,893,165 (+)	NCBI		HuRef
CHM1_1	11	4,115,391 - 4,159,561 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	4,159,950 - 4,204,024 (+)	NCBI		T2T-CHM13v2.0

Rrm1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	102,090,902 - 102,118,978 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	102,090,902 - 102,118,978 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	102,441,695 - 102,469,771 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	102,441,695 - 102,469,771 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	109,590,209 - 109,618,285 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	102,315,688 - 102,342,747 (+)	NCBI		MGSCv36	mm8
Celera	7	102,809,638 - 102,837,567 (+)	NCBI		Celera
Cytogenetic Map	7	E3	NCBI
cM Map	7	54.72	NCBI

Rrm1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	166,235,904 - 166,260,206 (+)	NCBI		GRCr8
mRatBN7.2	1	156,823,960 - 156,848,262 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	156,823,960 - 156,848,261 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	164,801,707 - 164,826,040 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	171,981,799 - 172,006,127 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	164,859,508 - 164,883,799 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	167,538,387 - 167,562,688 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	167,538,263 - 167,562,688 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	173,726,994 - 173,751,295 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	159,930,994 - 159,937,860 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	154,890,871 - 154,915,173 (+)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

Rrm1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	19,850,530 - 19,905,266 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	19,850,523 - 19,904,879 (+)	NCBI	ChiLan1.0	ChiLan1.0

RRM1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	6,348,683 - 6,392,806 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	5,588,407 - 5,632,547 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	3,956,528 - 3,999,205 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	4,068,119 - 4,110,474 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	4,068,119 - 4,110,474 (+)	Ensembl	panpan1.1		panPan2

RRM1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	26,595,838 - 26,631,476 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	26,595,914 - 26,631,135 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	26,365,162 - 26,400,602 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	26,805,233 - 26,840,936 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	26,805,323 - 26,840,930 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	26,595,614 - 26,630,876 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	26,811,885 - 26,847,337 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	26,714,390 - 26,749,830 (+)	NCBI		UU_Cfam_GSD_1.0

Rrm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	59,215,865 - 59,249,179 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936498	815,399 - 848,793 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936498	815,401 - 848,749 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RRM1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	62,606,112 - 62,649,979 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	62,604,486 - 62,650,200 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	63,252,138 - 63,296,602 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rrm1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624817	5,523,665 - 5,568,994 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624817	5,523,648 - 5,568,997 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RRM1
1670 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021062424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK351072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK389651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK396758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU466349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU467106	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01117270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000016142 ⟹ ENSSSCP00000015710

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	9	6,025,073 - 6,065,143 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000050049 ⟹ ENSSSCP00000040138

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	9	6,025,073 - 6,065,143 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000079973 ⟹ ENSSSCP00000065356

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	9	6,025,073 - 6,058,445 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000084455 ⟹ ENSSSCP00000062829

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	9	6,025,073 - 6,058,025 (-)	Ensembl

RefSeq Acc Id:

XM_021062424 ⟹ XP_020918083

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	9	6,026,151 - 6,065,211 (-)	NCBI

Sequence:

show sequence

CTCAACATGGCGGCTGCGGGACCAGGCCGACTCTTTGGCCGCCGTTACGGGCGGCGTCGCGTAA
CGTCATCGGAGCTCCGTTGTGCGGCTCCTGCGTCGCGGCTGGCGGGAGCGGGAAGGGGATTCGG
ATCGCGGTACTCGGCCCTGAGGGGAAAGTGCGCTCTGGCCTGGTTCCTGGCCCTGCACCCGAGC
AGCCCCTGGAGCTCTATCTTCCTCCGCGCTCTGCGCCGTCTGGATCCCGCCGACGCTTCGGAGT
TGCAGCCGCGTCTCGTATCCGTCAGCACCTCGTCCACCAGCGGCGATGCATGTAATCAAGCGAG
ATGGCCGCCAAGAGCGAGTTATGTTCGACAAAATCACATCTCGAATCCAGAAGCTTTGTTATGG
GCTGAATATGGACTTTGTTGATCCTGCTCAGATCACCATGAAAGTAATCCAAGGCTTATACAGC
GGGGTCACGACGGTGGAACTGGACACTTTGGCGGCTGAAACGGCTGCCACCCTGACGACTAAGC
ACCCTGACTATGCCATCCTGGCAGCGAGGATTGCCGTCTCCAACTTGCACAAAGAGACAAAGAA
AGTGTTCAGTGATGTGATGGAGGACCTCTTCAACTACATAAATCCGCACAACGGCAAACACTCT
CCCATGGTCGCCNAGTCAACGCTGGATATTGTTTTGGCCAATAAAGATCGCCTGAATTCTGCCA
TTATCTATGACCGAGATTTCTCTTACAATTACTTTGGCTTTAAGACGCTGGAGCGGTCCTATTT
GTTGAAGATCAGTGGAAAAGTGGCCGAAAGACCACAGCATATGTTGATGAGGGTATCTGTGGGG
ATTCACAAAGAAGATATTGATGCTGCTATTGAAACATACAACCTTCTTTCTGAGAAGTGGTTTA
CCCATGCCTCGCCCACTCTCTTCAATGCTGGCACCAACCGCCCACAGCTCTCTAGCTGTTTCCT
TCTGAGTATGAAAGATGATAGCATTGAAGGCATTTATGACACTCTAAAGCAGTGTGCATTGATT
TCCAAGTCAGCTGGGGGAATTGGTGTTGCTGTGAGTTGTATTCGAGCTACTGGCAGCTACATTG
CTGGGACGAATGGCAATTCCAACGGCCTTGTGCCGATGCTGAGAGTGTATAACAACACAGCTCG
ATACGTGGATCAGGGTGGAAACAAGCGACCTGGGGCATTTGCTATTTATCTGGAGCCTTGGCAT
TTAGACATCTTTGAGTTCCTTGATTTAAAGAAGAACACAGGGAAGGAAGAGCAGCGTGCCAGGG
ACCTCTTCTTTGCCCTTTGGATTCCGGATCTCTTCATGAAGCGAGTGGAGACGAATCAGGACTG
GTCCTTGATGTGTCCAAATGAGTGTCCTGGTCTGGATGAGGTCTGGGGAGAAGAATTTGAGAAG
CTATATGAAAGTTATGAGAGACAGGGTCATGTCCGCAAGGTTGTAAAAGCTCAGCAGCTTTGGT
ATGCCATCATCGAGTCGCAGACAGAGACAGGAACCCCATACATGCTCTACAAAGATTCCTGTAA
TCGGAAGAGCAACCAGCAGAACCTGGGAACAATCAAATGCAGCAACCTGTGCACAGAAATAGTG
GAGTACACCAGCAAAGATGAGGTTGCAGTTTGTAACTTGGCTTCCCTGGCCCTGAATATGTATG
TTACATCAGAACACACATATGACTTTACCAAGTTAGCTGAAGTCACCAAAGTTATTGTCCGAAA
CTTAAATAAAATCATTGATATTAACTACTACCCTATCCCAGAGGCAAGTTTATCAAATAAACGC
CATCGCCCCATTGGAATTGGGGTACAAGGTCTGGCAGATGCTTTTATTCTGATGAGATACCCTT
TTGAGAGTCCAGAGGCCCAGTTATTGAATAAGCAGATCTTTGAAACCATCTATTATGGAGCCTT
GGAAGCTAGCTGTGACCTGGCCAAGGAGTATGGCCCCTATGAAACCTATGAGGGCTCTCCAGTC
AGCAAAGGAATCCTTCAGTACGACATGTGGAACGTTACTCCTACAGACCTGTGGGACTGGAAGC
TCCTGAAGGAGAAGATTGCGAAGTATGGCATACGAAACAGCTTACTTATCGCACCGATGCCTAC
TGCTTCCACCGCTCAGATTTTGGGAAATAATGAGTCCATTGAACCTTACACCAGTAATATCTAC
ACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCACTTACTGAAAGATCTTACGG
AGCGGGGCCTGTGGAATGAAGAGATGAAAAACCAGATTATTGCATGCAATGGCTCTATCCAGAG
CATACCAGAGATTCCTGATGACCTGAAGCAGCTTTATAAGACTGTATGGGAAATCTCCCAGAAA
ACTGTCCTCAAGATGGCAGCTGAGAGAGGCGCTTTCATTGATCAAAGCCAGTCTTTGAACATAC
ACATTGCTGAGCCCAACTATGGCAAACTCACGAGTATGCACTTCTACGGCTGGAAACAGGGTTT
GAAGACTGGGATGTATTATTTAAGGACAAGACCAGCAGCTAATCCGATCCAGTTCACTCTCAAT
AAGGAGAAGCTGAAAGATAAGGAAAAGGTTTCAAAAGAGGAGGAGAAGGAGAGGAACACGGCGG
CCATGGTGTGCTCTTTGGAGAACAGAGATGAATGTCTGATGTGTGGATCCTGAGGTTCGGCTTT
CGGGAGACCAGCGTTCCTTCAACAGCCAACGCTTCTTTAGCATAGTTCTTTGTAGTGGGTTTGC
TTGAAGTGGTGAGGCTTTGCTGGACCTTATTGAAGCAAAAGGATCAAATGATTTAAAGTATTGT
TTCTATATAAAGCGTGAAAGTAATGATTTTTAAAAGTTGATATATTGGGAATCAAATAGATGTT
TTAGGAATGCACCGGAAGCCATCTTGCAGACAGGGAGTGGTTAAGTAGGGCTTCATCACCCACC
CAGCACCCCTTTCCTGGTGACTTCAGTTTTGGTAGGGAGACTTAGTTTTGCTGCTCTGACTGGC
GTTTCCATAGAAGCAAAACTGAGTCATAACCTGTGAGAAGTGTTGACAGGACCTTTATCTGGAC
GAGGTCCTATTGGTCATTCTGAAATAAAGATACTCACCTATCCAAGTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020918083	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000015710.5
	ENSSSCP00000040138
	ENSSSCP00000040138.2
	ENSSSCP00000062829.1
	ENSSSCP00000065356.2
	ENSSSCP00025010211.1
	ENSSSCP00030013485.1
	ENSSSCP00035029951.1
	ENSSSCP00040041013.1
	ENSSSCP00045048337.1
	ENSSSCP00050010582.1
	ENSSSCP00055047190.1
	ENSSSCP00055047235.1
	ENSSSCP00055047254.1
	ENSSSCP00055047288.1
	ENSSSCP00055047304.1
	ENSSSCP00060040346.1
	ENSSSCP00065032473.1

RefSeq Acc Id:

XP_020918083 ⟸ XM_021062424

- UniProtKB:

A0A287A8J7 (UniProtKB/TrEMBL), A0A8D1T891 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETA
ATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLFNYINPHNGKHSPMVAXSTLDIVLANK
DRLNSAIIYDRDFSYNYFGFKTLERSYLLKISGKVAERPQHMLMRVSVGIHKEDIDAAIETYNL
LSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIR
ATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGK
EEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYERQGHVRKVV
KAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLAS
LALNMYVTSEHTYDFTKLAEVTKVIVRNLNKIIDINYYPIPEASLSNKRHRPIGIGVQGLADAF
ILMRYPFESPEAQLLNKQIFETIYYGALEASCDLAKEYGPYETYEGSPVSKGILQYDMWNVTPT
DLWDWKLLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPH
LLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQ
SQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEE
KERNTAAMVCSLENRDECLMCGS

hide sequence

Ensembl Acc Id:

ENSSSCP00000040138 ⟸ ENSSSCT00000050049

Ensembl Acc Id:

ENSSSCP00000015710 ⟸ ENSSSCT00000016142

Ensembl Acc Id:

ENSSSCP00000065356 ⟸ ENSSSCT00000079973

Ensembl Acc Id:

ENSSSCP00000062829 ⟸ ENSSSCT00000084455

Protein Domains

ATP-cone Ribonucleotide reductase large subunit

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000014791	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025017785	UniProtKB/TrEMBL
	ENSSSCG00030021610	UniProtKB/TrEMBL
	ENSSSCG00035055348	UniProtKB/TrEMBL
	ENSSSCG00040067287	UniProtKB/TrEMBL
	ENSSSCG00045039127	UniProtKB/TrEMBL
	ENSSSCG00050018713	UniProtKB/TrEMBL
	ENSSSCG00055029648	UniProtKB/TrEMBL
	ENSSSCG00060068366	UniProtKB/TrEMBL
	ENSSSCG00065054429	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000016142.5	UniProtKB/TrEMBL
	ENSSSCT00000050049	ENTREZGENE
	ENSSSCT00000050049.3	UniProtKB/TrEMBL
	ENSSSCT00000079973.2	UniProtKB/TrEMBL
	ENSSSCT00000084455.2	UniProtKB/TrEMBL
	ENSSSCT00025024137.1	UniProtKB/TrEMBL
	ENSSSCT00030030049.1	UniProtKB/TrEMBL
	ENSSSCT00035073835.1	UniProtKB/TrEMBL
	ENSSSCT00040092855.1	UniProtKB/TrEMBL
	ENSSSCT00045068009.1	UniProtKB/TrEMBL
	ENSSSCT00050025437.1	UniProtKB/TrEMBL
	ENSSSCT00055058924.1	UniProtKB/TrEMBL
	ENSSSCT00055058971.1	UniProtKB/TrEMBL
	ENSSSCT00055058991.1	UniProtKB/TrEMBL
	ENSSSCT00055059034.1	UniProtKB/TrEMBL
	ENSSSCT00055059051.1	UniProtKB/TrEMBL
	ENSSSCT00060093308.1	UniProtKB/TrEMBL
	ENSSSCT00065074556.1	UniProtKB/TrEMBL
Gene3D-CATH	3.20.70.20	UniProtKB/TrEMBL
InterPro	ATP-cone_dom	UniProtKB/TrEMBL
	NrdE_NrdA	UniProtKB/TrEMBL
	RNR_lg_C	UniProtKB/TrEMBL
	RNR_lsu_N	UniProtKB/TrEMBL
	RNR_R1-su_N	UniProtKB/TrEMBL
	Rrm1	UniProtKB/TrEMBL
NCBI Gene	RRM1	ENTREZGENE
PANTHER	PTHR11573	UniProtKB/TrEMBL
	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT	UniProtKB/TrEMBL
Pfam	ATP-cone	UniProtKB/TrEMBL
	Ribonuc_red_lgC	UniProtKB/TrEMBL
	Ribonuc_red_lgN	UniProtKB/TrEMBL
PRINTS	RIBORDTASEM1	UniProtKB/TrEMBL
PROSITE	ATP_CONE	UniProtKB/TrEMBL
	PROKAR_LIPOPROTEIN	UniProtKB/TrEMBL
	RIBORED_LARGE	UniProtKB/TrEMBL
Superfamily-SCOP	PFL-like glycyl radical enzymes	UniProtKB/TrEMBL
	SSF48168	UniProtKB/TrEMBL
UniProt	A0A287A8J7	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2QL80_PIG	UniProtKB/TrEMBL
	A0A5G2QLB4_PIG	UniProtKB/TrEMBL
	A0A8D0R364_PIG	UniProtKB/TrEMBL
	A0A8D1S4A2_PIG	UniProtKB/TrEMBL
	A0A8D1SD17_PIG	UniProtKB/TrEMBL
	A0A8D1SH25_PIG	UniProtKB/TrEMBL
	A0A8D1T891	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1Z6B1_PIG	UniProtKB/TrEMBL
	F1SUZ5_PIG	UniProtKB/TrEMBL
VGNC ID	VGNC:92461	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

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Imported Disease Annotations - OMIM

Imported Annotations - SMPDB