TYSND1 (trypsin like peroxisomal matrix peptidase 1) - Rat Genome Database

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Gene: TYSND1 (trypsin like peroxisomal matrix peptidase 1) Sus scrofa
Analyze
Symbol: TYSND1
Name: trypsin like peroxisomal matrix peptidase 1
RGD ID: 14012233
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN protein processing (inferred); proteolysis (inferred); regulation of fatty acid beta-oxidation (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN peroxisome (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peroxisomal leader peptide-processing protease; trypsin domain containing 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1473,077,168 - 73,088,790 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11473,079,557 - 73,089,618 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21478,998,883 - 79,008,118 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
peroxisome  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:30032202  


Genomics

Comparative Map Data
TYSND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1473,077,168 - 73,088,790 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11473,079,557 - 73,089,618 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21478,998,883 - 79,008,118 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TYSND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381070,137,981 - 70,146,700 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1070,137,981 - 70,146,700 (-)EnsemblGRCh38hg38GRCh38
GRCh371071,897,737 - 71,906,456 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361071,567,739 - 71,576,502 (-)NCBINCBI36Build 36hg18NCBI36
Build 341071,568,973 - 71,576,442NCBI
Celera1065,176,845 - 65,185,592 (-)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1065,890,229 - 65,898,970 (-)NCBIHuRef
CHM1_11072,179,790 - 72,188,545 (-)NCBICHM1_1
T2T-CHM13v2.01071,006,917 - 71,015,621 (-)NCBIT2T-CHM13v2.0
Tysnd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391061,531,279 - 61,538,552 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1061,531,293 - 61,538,552 (+)EnsemblGRCm39 Ensembl
GRCm381061,695,500 - 61,702,773 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1061,695,514 - 61,702,773 (+)EnsemblGRCm38mm10GRCm38
MGSCv371061,158,262 - 61,165,521 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361061,090,871 - 61,098,130 (+)NCBIMGSCv36mm8
Celera1062,797,020 - 62,804,281 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.26NCBI
Tysnd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82030,180,878 - 30,188,239 (+)NCBIGRCr8
mRatBN7.22029,637,942 - 29,646,492 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2029,638,277 - 29,643,995 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2030,649,263 - 30,654,981 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,040,470 - 30,046,188 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02030,782,949 - 30,788,667 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02031,313,018 - 31,318,736 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2031,313,018 - 31,318,736 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02033,110,493 - 33,116,211 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42029,062,966 - 29,068,684 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12029,076,823 - 29,081,933 (+)NCBI
Celera2031,065,758 - 31,071,476 (+)NCBICelera
Cytogenetic Map20q11NCBI
Tysnd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543721,096,164 - 21,104,909 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543721,094,831 - 21,105,495 (+)NCBIChiLan1.0ChiLan1.0
TYSND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2882,286,698 - 82,302,090 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11082,295,815 - 82,304,935 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01066,609,736 - 66,619,838 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11069,140,994 - 69,148,495 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1069,141,724 - 69,148,346 (-)Ensemblpanpan1.1panPan2
SAR1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1421,120,788 - 21,136,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl421,123,028 - 21,136,973 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha421,253,559 - 21,269,768 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0421,396,755 - 21,413,021 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl421,396,755 - 21,413,169 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1421,294,359 - 21,310,594 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0421,499,331 - 21,515,693 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0421,850,363 - 21,866,661 (-)NCBIUU_Cfam_GSD_1.0
Tysnd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721359,949,907 - 59,957,496 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365218,442,193 - 8,450,928 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365218,442,175 - 8,450,221 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TYSND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1961,159,105 - 61,169,122 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl961,159,974 - 61,169,193 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604821,897,566 - 21,906,958 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tysnd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247544,300,710 - 4,312,145 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247544,304,955 - 4,312,155 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TYSND1
226 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 22 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011229   ⟹   ENSSSCP00000010937
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1473,077,168 - 73,088,790 (-)Ensembl
RefSeq Acc Id: XM_001927343   ⟹   XP_001927378
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,079,557 - 73,089,618 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001927378 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000010937
  ENSSSCP00000010937.3
  ENSSSCP00015004716.1
  ENSSSCP00030044583.1
  ENSSSCP00040015939.1
  ENSSSCP00045016296.1
  ENSSSCP00050022973.1
  ENSSSCP00070013715.1
Reference Protein Sequences
RefSeq Acc Id: XP_001927378   ⟸   XM_001927343
- UniProtKB: A0A4X1TFX8 (UniProtKB/TrEMBL),   A0A8D0MJV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010937   ⟸   ENSSSCT00000011229


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010259 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015009064 UniProtKB/TrEMBL
  ENSSSCG00030069114 UniProtKB/TrEMBL
  ENSSSCG00040028486 UniProtKB/TrEMBL
  ENSSSCG00045013825 UniProtKB/TrEMBL
  ENSSSCG00050040270 UniProtKB/TrEMBL
  ENSSSCG00070008565 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011229 ENTREZGENE
  ENSSSCT00000011229.5 UniProtKB/TrEMBL
  ENSSSCT00015011956.1 UniProtKB/TrEMBL
  ENSSSCT00030096699.1 UniProtKB/TrEMBL
  ENSSSCT00040038205.1 UniProtKB/TrEMBL
  ENSSSCT00045023597.1 UniProtKB/TrEMBL
  ENSSSCT00050054446.1 UniProtKB/TrEMBL
  ENSSSCT00070016561.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  TYSND1/DEG15 UniProtKB/TrEMBL
KEGG Report ssc:100157601 UniProtKB/TrEMBL
NCBI Gene TYSND1 ENTREZGENE
PANTHER PEROXISOMAL LEADER PEPTIDE-PROCESSING PROTEASE UniProtKB/TrEMBL
  PTHR21004 UniProtKB/TrEMBL
Pfam Trypsin_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A4X1TFX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MJV2 ENTREZGENE, UniProtKB/TrEMBL
  F1SUE6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:94621 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-08-03 TYSND1  trypsin like peroxisomal matrix peptidase 1  TYSND1  trypsin domain containing 1  Symbol and/or name change 19259463 PROVISIONAL