PTGIR (prostaglandin I2 receptor) - Rat Genome Database
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Gene: PTGIR (prostaglandin I2 receptor) Sus scrofa
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Symbol: PTGIR
Name: prostaglandin I2 receptor
RGD ID: 14010476
Description: INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); negative regulation of platelet-derived growth factor receptor signaling pathway (ortholog); negative regulation of smooth muscle cell proliferation (ortholog); PARTICIPATES IN eicosanoid signaling pathway; prostaglandin I2 signaling pathway; ASSOCIATED WITH aspirin-induced respiratory disease (ortholog); heart disease (ortholog); Walker-Warburg syndrome (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: prostacyclin receptor; prostaglandin I2 (prostacyclin) receptor (IP)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,522,630 - 52,527,613 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,522,639 - 52,527,338 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,842,083 - 47,847,155 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:24954635   PMID:26069941  


Genomics

Comparative Map Data
PTGIR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,522,630 - 52,527,613 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,522,639 - 52,527,338 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,842,083 - 47,847,155 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTGIR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1946,620,468 - 46,625,089 (-)EnsemblGRCh38hg38GRCh38
GRCh381946,610,040 - 46,625,097 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371947,123,725 - 47,128,346 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371947,114,585 - 47,128,375 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,815,565 - 51,820,194 (-)NCBINCBI36hg18NCBI36
Build 341951,815,565 - 51,820,194NCBI
Celera1943,927,252 - 43,931,881 (-)NCBI
Cytogenetic Map19q13.32NCBI
HuRef1943,548,741 - 43,553,370 (-)NCBIHuRef
CHM1_11947,125,572 - 47,130,201 (-)NCBICHM1_1
Ptgir
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,640,415 - 16,644,830 (+)NCBIGRCm39mm39
GRCm38716,906,490 - 16,910,905 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,906,490 - 16,910,905 (+)EnsemblGRCm38mm10GRCm38
MGSCv37717,491,839 - 17,496,254 (+)NCBIGRCm37mm9NCBIm37
MGSCv36716,065,012 - 16,069,427 (+)NCBImm8
Celera714,112,908 - 14,117,323 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
Ptgir
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2177,579,596 - 77,581,979 (+)NCBI
Rnor_6.0 Ensembl178,833,157 - 78,837,623 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0178,833,449 - 78,835,832 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0180,080,854 - 80,083,237 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,234,538 - 77,236,921 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1177,312,476 - 77,315,005 (+)NCBI
Celera172,064,851 - 72,067,234 (+)NCBICelera
Cytogenetic Map1q21NCBI
Ptgir
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574687,583 - 689,750 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955574686,156 - 690,126 (-)NCBIChiLan1.0ChiLan1.0
PTGIR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11952,141,822 - 52,146,473 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,141,822 - 52,146,473 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01943,613,065 - 43,617,700 (-)NCBIMhudiblu_PPA_v0panPan3
PTGIR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1109,274,988 - 109,277,584 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11109,275,198 - 109,279,463 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ptgir
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936664487,069 - 489,328 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGIR
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,977,057 - 39,983,592 (-)NCBI
ChlSab1.1 Ensembl639,977,864 - 39,980,860 (-)Ensembl
Ptgir
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248326,948,638 - 6,952,664 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 5 2 5 1 1
Below cutoff 5 1 2 8 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000026559   ⟹   ENSSSCP00000027306
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl652,522,630 - 52,527,613 (-)Ensembl
RefSeq Acc Id: XM_003355952   ⟹   XP_003356000
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,522,639 - 52,527,338 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003356000 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003356000   ⟸   XM_003355952
- UniProtKB: I3LT62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000027306   ⟸   ENSSSCT00000026559
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000026602 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070028194 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000027306 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070048054 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000026559 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070056560 UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Prostanoid_rcpt UniProtKB/TrEMBL
  Prostglndn_IP_rcpt UniProtKB/TrEMBL
KEGG Report ssc:100622305 UniProtKB/TrEMBL
NCBI Gene PTGIR ENTREZGENE
PANTHER PTHR11866 UniProtKB/TrEMBL
  PTHR11866:SF7 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  PROSTANOIDR UniProtKB/TrEMBL
  PRSTNOIDIPR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
UniProt A0A4X1W284_PIG UniProtKB/TrEMBL
  I3LT62 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91956 ENTREZGENE