EFEMP2 (EGF containing fibulin extracellular matrix protein 2) - Rat Genome Database

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Gene: EFEMP2 (EGF containing fibulin extracellular matrix protein 2) Sus scrofa
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Symbol: EFEMP2
Name: EGF containing fibulin extracellular matrix protein 2
RGD ID: 14003514
Description: ENCODES a protein that exhibits calcium ion binding (inferred); heparin binding (inferred); protein homodimerization activity (inferred); INVOLVED IN aorta development (ortholog); aorta smooth muscle tissue morphogenesis (ortholog); artery development (ortholog); ASSOCIATED WITH aortic aneurysm (ortholog); aortic dissection (ortholog); arterial tortuosity syndrome (ortholog); FOUND IN basement membrane (ortholog); microfibril (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EGF containing fibulin like extracellular matrix protein 2; EGF-containing fibulin-like extracellular matrix protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,450,332 - 6,463,486 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,455,155 - 6,463,493 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,559,189 - 5,567,521 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:17145712  


Genomics

Comparative Map Data
EFEMP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,450,332 - 6,463,486 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,455,155 - 6,463,493 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,559,189 - 5,567,521 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EFEMP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,866,441 - 65,872,800 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1165,866,441 - 65,873,592 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,633,912 - 65,640,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,390,488 - 65,396,852 (-)NCBINCBI36Build 36hg18NCBI36
Build 341165,390,494 - 65,396,793NCBI
Celera1162,957,818 - 62,964,246 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1161,960,429 - 61,966,923 (-)NCBIHuRef
CHM1_11165,518,326 - 65,524,819 (-)NCBICHM1_1
T2T-CHM13v2.01165,860,912 - 65,867,272 (-)NCBIT2T-CHM13v2.0
Efemp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,523,974 - 5,532,548 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,523,982 - 5,532,545 (+)EnsemblGRCm39 Ensembl
GRCm38195,473,946 - 5,482,520 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,473,954 - 5,482,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,474,690 - 5,481,854 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,474,750 - 5,481,853 (+)NCBIMGSCv36mm8
Celera195,346,431 - 5,353,554 (+)NCBICelera
Cytogenetic Map19ANCBI
Efemp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21202,781,692 - 202,789,784 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1202,781,665 - 202,789,414 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,134,675 - 211,141,697 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01218,227,788 - 218,234,806 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01210,918,833 - 210,925,850 (+)NCBIRnor_WKY
Rnor_6.01220,853,695 - 220,861,420 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,854,403 - 220,861,420 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,783,038 - 227,790,741 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,118,537 - 208,125,490 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11208,271,989 - 208,278,942 (+)NCBI
Celera1200,318,443 - 200,324,890 (+)NCBICelera
Cytogenetic Map1q43NCBI
Efemp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,463,987 - 19,470,605 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,463,090 - 19,470,605 (+)NCBIChiLan1.0ChiLan1.0
EFEMP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11164,555,877 - 64,561,950 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,555,877 - 64,561,950 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01161,226,755 - 61,233,181 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
EFEMP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,389,797 - 51,396,109 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,389,824 - 51,396,107 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1849,997,510 - 50,004,619 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01852,427,071 - 52,434,176 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1852,427,841 - 52,434,176 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11851,527,128 - 51,534,242 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01851,101,501 - 51,108,618 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01851,890,821 - 51,897,925 (+)NCBIUU_Cfam_GSD_1.0
Efemp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,221,048 - 7,228,320 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365993,663,326 - 3,670,047 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365993,663,288 - 3,670,048 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFEMP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118,384,212 - 8,391,501 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl18,385,020 - 8,390,889 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038105,673,390 - 105,680,538 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Efemp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,559,795 - 20,566,341 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,559,801 - 20,566,326 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 22 2 3 1
Below cutoff 1 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000014178   ⟹   ENSSSCP00000013792
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl26,455,894 - 6,462,980 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000045779   ⟹   ENSSSCP00000041678
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl26,450,332 - 6,462,973 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000054224   ⟹   ENSSSCP00000056455
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl26,455,346 - 6,463,486 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000076739   ⟹   ENSSSCP00000062020
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl26,455,564 - 6,462,978 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000095338   ⟹   ENSSSCP00000076004
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl26,455,346 - 6,463,486 (+)Ensembl
RefSeq Acc Id: XM_005660679   ⟹   XP_005660736
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.126,455,155 - 6,463,493 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005660736 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005660736   ⟸   XM_005660679
- UniProtKB: A0A287ACR0 (UniProtKB/TrEMBL),   A0A8D2BZY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000056455   ⟸   ENSSSCT00000054224
RefSeq Acc Id: ENSSSCP00000041678   ⟸   ENSSSCT00000045779
RefSeq Acc Id: ENSSSCP00000062020   ⟸   ENSSSCT00000076739
RefSeq Acc Id: ENSSSCP00000013792   ⟸   ENSSSCT00000014178
RefSeq Acc Id: ENSSSCP00000076004   ⟸   ENSSSCT00000095338
Protein Domains
EGF-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012971 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015061312 UniProtKB/TrEMBL
  ENSSSCG00025077157 UniProtKB/TrEMBL
  ENSSSCG00030019625 UniProtKB/TrEMBL
  ENSSSCG00035070199 UniProtKB/TrEMBL
  ENSSSCG00040067234 UniProtKB/TrEMBL
  ENSSSCG00045025220 UniProtKB/TrEMBL
  ENSSSCG00050061630 UniProtKB/TrEMBL
  ENSSSCG00055013496 UniProtKB/TrEMBL
  ENSSSCG00060071038 UniProtKB/TrEMBL
  ENSSSCG00065013213 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000013792.4 UniProtKB/TrEMBL
  ENSSSCP00000041678 ENTREZGENE
  ENSSSCP00000041678.2 UniProtKB/TrEMBL
  ENSSSCP00000056455.2 UniProtKB/TrEMBL
  ENSSSCP00000062020.1 UniProtKB/TrEMBL
  ENSSSCP00000076004.1 UniProtKB/TrEMBL
  ENSSSCP00015033221.1 UniProtKB/TrEMBL
  ENSSSCP00025048332.1 UniProtKB/TrEMBL
  ENSSSCP00030012112.1 UniProtKB/TrEMBL
  ENSSSCP00035039926.1 UniProtKB/TrEMBL
  ENSSSCP00040040830.1 UniProtKB/TrEMBL
  ENSSSCP00045029861.1 UniProtKB/TrEMBL
  ENSSSCP00050036035.1 UniProtKB/TrEMBL
  ENSSSCP00055021170.1 UniProtKB/TrEMBL
  ENSSSCP00060042185.1 UniProtKB/TrEMBL
  ENSSSCP00065007208.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000014178.5 UniProtKB/TrEMBL
  ENSSSCT00000045779 ENTREZGENE
  ENSSSCT00000045779.3 UniProtKB/TrEMBL
  ENSSSCT00000054224.3 UniProtKB/TrEMBL
  ENSSSCT00000076739.1 UniProtKB/TrEMBL
  ENSSSCT00000095338.1 UniProtKB/TrEMBL
  ENSSSCT00015082122.1 UniProtKB/TrEMBL
  ENSSSCT00025107237.1 UniProtKB/TrEMBL
  ENSSSCT00030027192.1 UniProtKB/TrEMBL
  ENSSSCT00035094969.1 UniProtKB/TrEMBL
  ENSSSCT00040092494.1 UniProtKB/TrEMBL
  ENSSSCT00045042984.1 UniProtKB/TrEMBL
  ENSSSCT00050083967.1 UniProtKB/TrEMBL
  ENSSSCT00055026632.1 UniProtKB/TrEMBL
  ENSSSCT00060097300.1 UniProtKB/TrEMBL
  ENSSSCT00065017648.1 UniProtKB/TrEMBL
InterPro cEGF UniProtKB/TrEMBL
  Efemp2 UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
KEGG Report ssc:100526031 UniProtKB/TrEMBL
NCBI Gene EFEMP2 ENTREZGENE
PANTHER PTHR24034:SF96 UniProtKB/TrEMBL
Pfam cEGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/TrEMBL
UniProt A0A287ACR0 ENTREZGENE, UniProtKB/TrEMBL
  A0A287BIU2_PIG UniProtKB/TrEMBL
  A0A5G2QD21_PIG UniProtKB/TrEMBL
  A0A8D2BZY5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4F9D3_PIG UniProtKB/TrEMBL
  F1RU22_PIG UniProtKB/TrEMBL
VGNC ID VGNC:99643 ENTREZGENE