DRC3 (dynein regulatory complex subunit 3) - Rat Genome Database

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Gene: DRC3 (dynein regulatory complex subunit 3) Sus scrofa
Analyze
Symbol: DRC3
Name: dynein regulatory complex subunit 3
RGD ID: 14002575
Description: ASSOCIATED WITH autistic disorder (ortholog); Birt-Hogg-Dube syndrome (ortholog); common variable immunodeficiency 2 (ortholog); FOUND IN axoneme (inferred); cilium (inferred); cytoplasm (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,633,177 - 60,651,849 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,633,166 - 60,651,821 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axoneme  (IEA)
cilium  (IBA,IEA)
cytoplasm  (IEA)
motile cilium  (IEA)
sperm flagellum  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074  


Genomics

Comparative Map Data
DRC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,633,177 - 60,651,849 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,633,166 - 60,651,821 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DRC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381717,972,813 - 18,016,889 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1717,972,813 - 18,016,889 (+)EnsemblGRCh38hg38GRCh38
GRCh371717,876,127 - 17,920,203 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361717,816,924 - 17,860,898 (+)NCBINCBI36Build 36hg18NCBI36
Celera1718,816,897 - 18,861,264 (+)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1717,629,874 - 17,673,986 (+)NCBIHuRef
CHM1_11717,884,945 - 17,929,004 (+)NCBICHM1_1
T2T-CHM13v2.01717,919,490 - 17,963,683 (+)NCBIT2T-CHM13v2.0
Drc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,243,063 - 60,285,168 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1160,244,155 - 60,285,167 (+)EnsemblGRCm39 Ensembl
GRCm381160,352,881 - 60,394,342 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,353,329 - 60,394,341 (+)EnsemblGRCm38mm10GRCm38
MGSCv371160,166,882 - 60,207,835 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361160,903,173 - 60,932,554 (+)NCBIMGSCv36mm8
MGSCv361160,169,575 - 60,210,528 (+)NCBIMGSCv36mm8
Cytogenetic Map11B2NCBI
cM Map1137.81NCBI
Drc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81045,620,045 - 45,698,902 (+)NCBIGRCr8
mRatBN7.21045,149,094 - 45,200,659 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,157,354 - 45,199,369 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1049,859,561 - 49,899,746 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01049,349,935 - 49,390,124 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01044,853,532 - 44,893,727 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01046,712,021 - 46,762,276 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1046,722,109 - 46,762,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,466,517 - 46,517,603 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,614,082 - 46,662,673 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11046,627,704 - 46,676,287 (+)NCBI
Celera1044,416,605 - 44,456,596 (+)NCBICelera
Cytogenetic Map10q22NCBI
DRC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21952,487,501 - 52,533,360 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11757,204,737 - 57,246,856 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01733,278,528 - 33,324,351 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11738,226,287 - 38,272,013 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1738,226,305 - 38,272,013 (-)Ensemblpanpan1.1panPan2
DRC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1541,499,810 - 41,534,641 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl541,499,815 - 41,534,549 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha541,638,860 - 41,673,691 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0541,606,191 - 41,641,024 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl541,606,196 - 41,640,929 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1541,573,922 - 41,608,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0541,521,329 - 41,556,151 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0541,713,217 - 41,748,048 (-)NCBIUU_Cfam_GSD_1.0
Drc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560261,272,175 - 61,311,357 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367411,555,941 - 1,594,898 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367411,555,981 - 1,595,077 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11617,009,632 - 17,056,744 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1617,010,290 - 17,056,733 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660593,851,892 - 3,899,566 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Drc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248493,429,932 - 3,466,481 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248493,429,932 - 3,466,172 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DRC3
504 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 22 2 3 3
Below cutoff 1 1

Sequence


RefSeq Acc Id: ENSSSCT00000046987   ⟹   ENSSSCP00000034227
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1260,633,177 - 60,651,849 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000051175   ⟹   ENSSSCP00000041364
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1260,633,177 - 60,651,681 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000094809   ⟹   ENSSSCP00000080198
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1260,633,177 - 60,651,849 (-)Ensembl
RefSeq Acc Id: XM_021067999   ⟹   XP_020923658
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11260,633,166 - 60,651,812 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068000   ⟹   XP_020923659
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11260,633,166 - 60,651,808 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068001   ⟹   XP_020923660
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11260,633,166 - 60,651,808 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068002   ⟹   XP_020923661
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11260,633,166 - 60,651,806 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068003   ⟹   XP_020923662
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11260,633,166 - 60,651,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068004   ⟹   XP_020923663
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11260,633,166 - 60,651,817 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020923662   ⟸   XM_021068003
- Peptide Label: isoform X5
- UniProtKB: A0A4X1STS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020923663   ⟸   XM_021068004
- Peptide Label: isoform X6
- UniProtKB: A0A4X1STS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020923658   ⟸   XM_021067999
- Peptide Label: isoform X1
- UniProtKB: A0A4X1STS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020923660   ⟸   XM_021068001
- Peptide Label: isoform X3
- UniProtKB: A0A4X1STS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020923659   ⟸   XM_021068000
- Peptide Label: isoform X2
- UniProtKB: A0A4X1STS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020923661   ⟸   XM_021068002
- Peptide Label: isoform X4
- UniProtKB: A0A480MS13 (UniProtKB/TrEMBL),   A0A8D1QTV4 (UniProtKB/TrEMBL),   A0A4X1STS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000041364   ⟸   ENSSSCT00000051175
RefSeq Acc Id: ENSSSCP00000034227   ⟸   ENSSSCT00000046987
RefSeq Acc Id: ENSSSCP00000080198   ⟸   ENSSSCT00000094809


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037557 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015065291 UniProtKB/TrEMBL
  ENSSSCG00030024435 UniProtKB/TrEMBL
  ENSSSCG00045003785 UniProtKB/TrEMBL
  ENSSSCG00050053841 UniProtKB/TrEMBL
  ENSSSCG00055016409 UniProtKB/TrEMBL
  ENSSSCG00060076179 UniProtKB/TrEMBL
  ENSSSCG00070004008 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000046987.3 UniProtKB/TrEMBL
  ENSSSCT00000051175.3 UniProtKB/TrEMBL
  ENSSSCT00000094809 ENTREZGENE
  ENSSSCT00000094809.1 UniProtKB/TrEMBL
  ENSSSCT00015087551.1 UniProtKB/TrEMBL
  ENSSSCT00030034045.1 UniProtKB/TrEMBL
  ENSSSCT00030034052.1 UniProtKB/TrEMBL
  ENSSSCT00045006278.1 UniProtKB/TrEMBL
  ENSSSCT00045006289.1 UniProtKB/TrEMBL
  ENSSSCT00050073394.1 UniProtKB/TrEMBL
  ENSSSCT00055032745.1 UniProtKB/TrEMBL
  ENSSSCT00060104480.1 UniProtKB/TrEMBL
  ENSSSCT00070007549.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene DRC3 ENTREZGENE
PANTHER DYNEIN REGULATORY COMPLEX SUBUNIT 3 UniProtKB/TrEMBL
  PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED UniProtKB/TrEMBL
Pfam LRR_9 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A286ZRH2_PIG UniProtKB/TrEMBL
  A0A287ABI6_PIG UniProtKB/TrEMBL
  A0A480MS13 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1STS0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1C3P6_PIG UniProtKB/TrEMBL
  A0A8D1GJ04_PIG UniProtKB/TrEMBL
  A0A8D1KQL4_PIG UniProtKB/TrEMBL
  A0A8D1QTV4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:87441 ENTREZGENE