SLC14A2 (solute carrier family 14 member 2) - Rat Genome Database

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Gene: SLC14A2 (solute carrier family 14 member 2) Sus scrofa
Analyze
Symbol: SLC14A2
Name: solute carrier family 14 member 2
RGD ID: 13996845
Description: ENCODES a protein that exhibits urea transmembrane transporter activity (ortholog); INVOLVED IN urea transmembrane transport (ortholog); urea transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Microcephaly, Epilepsy, and Diabetes Syndrome (ortholog); FOUND IN basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: solute carrier family 14 (urea transporter), member 2; urea transporter 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl195,255,632 - 95,320,542 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1194,838,955 - 95,322,748 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21105,368,929 - 105,382,578 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC14A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl195,255,632 - 95,320,542 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1194,838,955 - 95,322,748 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21105,368,929 - 105,382,578 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC14A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381845,167,963 - 45,683,688 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1845,212,995 - 45,683,688 (+)EnsemblGRCh38hg38GRCh38
GRCh371842,747,928 - 43,263,653 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361841,448,764 - 41,517,070 (+)NCBINCBI36Build 36hg18NCBI36
Build 341841,448,763 - 41,517,056NCBI
Celera1840,003,033 - 40,071,376 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
HuRef1839,650,605 - 40,120,200 (+)NCBIHuRef
CHM1_11842,719,963 - 43,190,313 (+)NCBICHM1_1
T2T-CHM13v2.01845,359,240 - 45,874,622 (+)NCBIT2T-CHM13v2.0
Slc14a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391878,189,359 - 78,640,165 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1878,189,363 - 78,640,157 (-)EnsemblGRCm39 Ensembl
GRCm381878,146,144 - 78,596,950 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1878,146,148 - 78,596,942 (-)EnsemblGRCm38mm10GRCm38
MGSCv371878,342,883 - 78,793,689 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361878,308,224 - 78,759,020 (-)NCBIMGSCv36mm8
Celera1879,287,387 - 79,738,811 (-)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1852.53NCBI
Slc14a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21871,612,460 - 72,039,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1871,612,460 - 71,792,968 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1873,711,878 - 74,138,787 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01874,381,161 - 74,808,122 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01872,237,749 - 72,664,708 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01874,508,070 - 74,941,389 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1874,508,069 - 74,542,077 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1874,546,220 - 74,688,551 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01874,185,426 - 74,617,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41875,071,416 - 75,499,738 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11875,144,693 - 75,325,630 (-)NCBI
Celera1870,129,421 - 70,555,892 (-)NCBICelera
Cytogenetic Map18q12.3NCBI
Slc14a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540231,115,937 - 31,285,228 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540230,877,808 - 31,283,983 (+)NCBIChiLan1.0ChiLan1.0
SLC14A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21763,050,743 - 63,110,153 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11848,743,343 - 48,802,753 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01838,766,994 - 38,966,124 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11842,034,675 - 42,506,485 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1842,448,067 - 42,506,485 (+)Ensemblpanpan1.1panPan2
SLC14A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1745,435,387 - 45,868,977 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl745,431,450 - 45,490,430 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha745,019,276 - 45,354,276 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0745,413,685 - 45,883,152 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1745,113,465 - 45,589,519 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0745,166,683 - 45,635,665 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0745,451,135 - 45,920,415 (-)NCBIUU_Cfam_GSD_1.0
LOC101965929
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494441,732,909 - 41,759,360 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365171,061,119 - 1,104,768 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365171,060,311 - 1,104,775 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC14A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11835,209,672 - 35,684,142 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1835,209,267 - 35,404,626 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660509,581,381 - 9,639,922 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc14a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247789,330,064 - 9,379,942 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247788,943,209 - 9,379,942 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC14A2
10746 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system nervous system reproductive system
High
Medium
Low 2 2 7
Below cutoff 2 10 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000004962   ⟹   ENSSSCP00000004845
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl195,255,632 - 95,320,542 (+)Ensembl
RefSeq Acc Id: XM_021092457   ⟹   XP_020948116
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1194,838,955 - 95,322,748 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020948116 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000004845
  ENSSSCP00000004845.4
Reference Protein Sequences
RefSeq Acc Id: XP_020948116   ⟸   XM_021092457
- UniProtKB: F1RQG4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000004845   ⟸   ENSSSCT00000004962


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004491 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004962 ENTREZGENE
  ENSSSCT00000004962.4 UniProtKB/TrEMBL
Gene3D-CATH 1.10.3430.10 UniProtKB/TrEMBL
InterPro Ammonium/urea_transptr UniProtKB/TrEMBL
  Urea_transporter UniProtKB/TrEMBL
NCBI Gene SLC14A2 ENTREZGENE
PANTHER PTHR10464 UniProtKB/TrEMBL
  UREA TRANSPORTER 2 UniProtKB/TrEMBL
Pfam PF03253 UniProtKB/TrEMBL
UniProt F1RQG4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92933 ENTREZGENE