ZFP57 (ZFP57 zinc finger protein) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ZFP57 (ZFP57 zinc finger protein) Sus scrofa
Analyze
Symbol: ZFP57
Name: ZFP57 zinc finger protein
RGD ID: 13994846
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); double-stranded methylated DNA binding (ortholog); INVOLVED IN DNA methylation involved in embryo development (ortholog); genetic imprinting (ortholog); maintenance of DNA methylation (ortholog); PARTICIPATES IN DNA modification pathway; ASSOCIATED WITH diabetes mellitus (ortholog); transient neonatal diabetes mellitus (ortholog); Transient Neonatal Diabetes Mellitus, 1 (ortholog); FOUND IN heterochromatin (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: KRAB; KRAB box; zinc finger protein 57 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,605,125 - 22,612,064 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,607,420 - 22,612,064 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2725,016,155 - 25,020,986 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
heterochromatin  (ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16328468  


Genomics

Comparative Map Data
ZFP57
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,605,125 - 22,612,064 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,607,420 - 22,612,064 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2725,016,155 - 25,020,986 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZFP57
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl629,672,483 - 29,681,155 (-)EnsemblGRCh38hg38GRCh38
GRCh38629,672,392 - 29,681,152 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37629,640,169 - 29,648,929 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,748,239 - 29,756,866 (-)NCBINCBI36hg18NCBI36
Celera631,246,246 - 31,251,015 (-)NCBI
Cytogenetic Map6p22.1NCBI
HuRef629,447,209 - 29,452,012 (-)NCBIHuRef
CHM1_1629,642,261 - 29,647,014 (-)NCBICHM1_1
Zfp57
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,307,060 - 37,326,196 (+)NCBIGRCm39mm39
GRCm39 Ensembl1737,312,055 - 37,321,527 (+)Ensembl
GRCm381737,001,163 - 37,010,729 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,001,163 - 37,010,635 (+)EnsemblGRCm38mm10GRCm38
MGSCv371737,138,108 - 37,147,674 (+)NCBIGRCm37mm9NCBIm37
MGSCv361736,610,595 - 36,618,685 (+)NCBImm8
Celera1740,424,834 - 40,434,322 (+)NCBICelera
Cytogenetic Map17B1NCBI
Zfp57
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2201,521,323 - 1,534,884 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl201,521,323 - 1,529,846 (-)Ensembl
Rnor_6.0202,014,177 - 2,020,488 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl202,014,170 - 2,020,537 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0204,054,802 - 4,061,113 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,611,856 - 1,618,167 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1201,612,083 - 1,617,758 (-)NCBI
Celera202,231,911 - 2,238,222 (-)NCBICelera
Cytogenetic Map20p12NCBI
Zfp57
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955583151,338 - 154,827 (-)NCBIChiLan1.0ChiLan1.0
ZFP57
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1630,134,263 - 30,143,045 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl630,134,263 - 30,143,045 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0629,476,459 - 29,485,480 (-)NCBIMhudiblu_PPA_v0panPan3
ZFP57
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13526,267,358 - 26,269,429 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ROS_Cfam_1.03526,575,720 - 26,581,501 (-)NCBI
UMICH_Zoey_3.13526,230,410 - 26,236,187 (-)NCBI
UNSW_CanFamBas_1.03526,291,343 - 26,297,127 (-)NCBI
UU_Cfam_GSD_1.03527,761,408 - 27,767,190 (-)NCBI
Zfp57
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,520,334 - 32,532,225 (-)NCBI
SpeTri2.0NW_0049367231,063,969 - 1,069,986 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFP57
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11742,942,002 - 42,947,064 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604429,201,143 - 29,205,907 (-)NCBIVero_WHO_p1.0
Zfp57
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475425,390,107 - 25,397,205 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 20
Low 8 4 3 5 2 3 2 3 3
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000001361
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl722,605,125 - 22,612,064 (-)Ensembl
RefSeq Acc Id: NM_001123132   ⟹   NP_001116604
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1722,607,420 - 22,612,064 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001116604 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAD83380 (Get FASTA)   NCBI Sequence Viewer  
  BAD83385 (Get FASTA)   NCBI Sequence Viewer  
  BAG82677 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001116604   ⟸   NM_001123132
- UniProtKB: E2JL23 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
C2H2-type   KRAB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001247 Ensembl
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report ssc:100141415 UniProtKB/TrEMBL
NCBI Gene ZFP57 ENTREZGENE
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt B6ICU2_PIG UniProtKB/TrEMBL
  E2JL23 ENTREZGENE, UniProtKB/TrEMBL