ESYT3 (extended synaptotagmin 3) - Rat Genome Database

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Gene: ESYT3 (extended synaptotagmin 3) Sus scrofa
Analyze
Symbol: ESYT3
Name: extended synaptotagmin 3
RGD ID: 13987798
Description: ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent phospholipid binding (inferred); lipid binding (inferred); INVOLVED IN endoplasmic reticulum-plasma membrane tethering (inferred); lipid transport (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasmic side of plasma membrane (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: extended synaptotagmin-3; extended synaptotagmin-like protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1379,245,836 - 79,297,334 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11379,245,818 - 79,295,471 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21386,861,629 - 86,898,873 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ESYT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1379,245,836 - 79,297,334 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11379,245,818 - 79,295,471 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21386,861,629 - 86,898,873 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ESYT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383138,434,616 - 138,481,686 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3138,434,586 - 138,481,686 (+)EnsemblGRCh38hg38GRCh38
GRCh373138,153,458 - 138,200,528 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363139,636,109 - 139,678,399 (+)NCBINCBI36Build 36hg18NCBI36
Celera3136,578,324 - 136,622,170 (+)NCBICelera
Cytogenetic Map3q22.3NCBI
HuRef3135,528,375 - 135,572,226 (+)NCBIHuRef
CHM1_13138,117,188 - 138,161,034 (+)NCBICHM1_1
T2T-CHM13v2.03141,175,169 - 141,222,247 (+)NCBIT2T-CHM13v2.0
Esyt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39999,192,016 - 99,242,210 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl999,192,016 - 99,240,610 (-)EnsemblGRCm39 Ensembl
GRCm38999,309,963 - 99,360,159 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl999,309,963 - 99,358,557 (-)EnsemblGRCm38mm10GRCm38
MGSCv37999,210,386 - 99,258,949 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36999,119,495 - 99,167,882 (-)NCBIMGSCv36mm8
Celera998,843,495 - 98,893,869 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.54NCBI
Esyt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,749,761 - 108,796,630 (-)NCBIGRCr8
mRatBN7.2899,870,418 - 99,917,298 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,871,149 - 99,917,232 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.08107,555,417 - 107,602,414 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,555,277 - 107,602,263 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08106,981,121 - 107,027,963 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48104,171,726 - 104,216,761 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera899,272,485 - 99,319,481 (-)NCBICelera
Cytogenetic Map8q31NCBI
Esyt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955501538,538 - 585,505 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955501537,195 - 585,640 (-)NCBIChiLan1.0ChiLan1.0
ESYT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22136,340,722 - 136,384,571 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13136,345,050 - 136,392,918 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03135,463,698 - 135,509,417 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13142,913,450 - 142,958,684 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3142,913,450 - 142,958,684 (+)Ensemblpanpan1.1panPan2
ESYT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12334,645,248 - 34,692,178 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2334,645,087 - 34,691,939 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2334,639,173 - 34,685,862 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02335,187,397 - 35,234,172 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2335,187,162 - 35,233,932 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12334,868,467 - 34,915,155 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02334,934,284 - 34,980,995 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02335,185,169 - 35,231,861 (+)NCBIUU_Cfam_GSD_1.0
Esyt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560274,005,161 - 74,046,610 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936540744,980 - 785,113 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936540744,980 - 786,303 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESYT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11552,062,156 - 52,130,942 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1552,062,357 - 52,104,852 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604125,074,492 - 25,119,220 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Esyt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473014,986,750 - 15,033,870 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473014,986,583 - 15,035,163 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ESYT3
1219 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 2 3 5 23 2 3 3
Below cutoff 1 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000022823   ⟹   ENSSSCP00000020398
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1379,245,836 - 79,278,739 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000032135   ⟹   ENSSSCP00000021562
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1379,245,888 - 79,297,334 (+)Ensembl
RefSeq Acc Id: XM_003358571   ⟹   XP_003358619
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11379,245,818 - 79,295,471 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021069523   ⟹   XP_020925182
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11379,245,911 - 79,294,106 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002337696
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11379,245,911 - 79,290,576 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003358619   ⟸   XM_003358571
- Peptide Label: isoform X1
- UniProtKB: I3LBZ0 (UniProtKB/TrEMBL),   A0A4X1TGK7 (UniProtKB/TrEMBL),   A0A8D1CB81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925182   ⟸   XM_021069523
- Peptide Label: isoform X2
- UniProtKB: A0A480RR99 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000021562   ⟸   ENSSSCT00000032135
RefSeq Acc Id: ENSSSCP00000020398   ⟸   ENSSSCT00000022823
Protein Domains
C2   SMP-LTD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000027505 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005039989 UniProtKB/TrEMBL
  ENSSSCG00030050337 UniProtKB/TrEMBL
  ENSSSCG00035045529 UniProtKB/TrEMBL
  ENSSSCG00040037727 UniProtKB/TrEMBL
  ENSSSCG00045035889 UniProtKB/TrEMBL
  ENSSSCG00055029576 UniProtKB/TrEMBL
  ENSSSCG00060046852 UniProtKB/TrEMBL
  ENSSSCG00065054379 UniProtKB/TrEMBL
  ENSSSCG00070008979 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000022823.4 UniProtKB/TrEMBL
  ENSSSCT00000032135 ENTREZGENE
  ENSSSCT00000032135.4 UniProtKB/TrEMBL
  ENSSSCT00005064507.1 UniProtKB/TrEMBL
  ENSSSCT00030070167.1 UniProtKB/TrEMBL
  ENSSSCT00035060527.1 UniProtKB/TrEMBL
  ENSSSCT00040050622.1 UniProtKB/TrEMBL
  ENSSSCT00045061674.1 UniProtKB/TrEMBL
  ENSSSCT00055058778.1 UniProtKB/TrEMBL
  ENSSSCT00060063631.1 UniProtKB/TrEMBL
  ENSSSCT00065074520.1 UniProtKB/TrEMBL
  ENSSSCT00070017421.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  C2C_KIAA1228 UniProtKB/TrEMBL
  Ext_Synaptotagmin_C2A UniProtKB/TrEMBL
  Ext_Synaptotagmin_C2B UniProtKB/TrEMBL
  SMP_LBD UniProtKB/TrEMBL
  Synaptotagmin_SMP UniProtKB/TrEMBL
NCBI Gene ESYT3 ENTREZGENE
PANTHER EXTENDED SYNAPTOTAGMIN-3 UniProtKB/TrEMBL
  EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
  SMP_LBD UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
  SMP UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A480RR99 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TGK7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CB81 ENTREZGENE, UniProtKB/TrEMBL
  I3L8N8_PIG UniProtKB/TrEMBL
  I3LBZ0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:87798 ENTREZGENE