LOC110258194 (acetylserotonin O-methyltransferase-like) - Rat Genome Database

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Gene: LOC110258194 (acetylserotonin O-methyltransferase-like) Sus scrofa
Analyze
Symbol: LOC110258194
Name: acetylserotonin O-methyltransferase-like
RGD ID: 13986675
Description: ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity (ortholog); S-adenosylmethionine-dependent methyltransferase activity (ortholog); INVOLVED IN male gonad development (ortholog); melatonin biosynthetic process (ortholog); negative regulation of male gonad development (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Wilson disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LOC110258194
(Sus scrofa - pig)		 No map positions available.
ASMT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X1,615,059 - 1,643,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38Y1,615,059 - 1,643,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX1,615,059 - 1,643,081 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 EnsemblY1,615,059 - 1,643,081 (+)EnsemblGRCh38hg38GRCh38
GRCh37X1,714,348 - 1,761,974 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37Y1,664,348 - 1,711,974 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36Y1,674,348 - 1,721,974 (+)NCBINCBI36Build 36hg18NCBI36
Build 36X1,674,348 - 1,721,974 (+)NCBINCBI36Build 36hg18NCBI36
Build 34Y1,758,174 - 1,805,801NCBI
CeleraX5,992,483 - 6,035,986 (+)NCBICelera
Cytogenetic MapX;YNCBI
CHM1_1X1,744,907 - 1,789,431 (+)NCBICHM1_1
T2T-CHM13v2.0X1,416,353 - 1,441,907 (+)NCBIT2T-CHM13v2.0
T2T-CHM13v2.0Y1,478,823 - 1,502,882 (+)NCBIT2T-CHM13v2.0
Asmt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X169,106,379 - 169,111,787 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX169,106,280 - 169,112,125 (+)EnsemblGRCm39 Ensembl
GRCm38X170,672,644 - 170,678,054 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX170,672,644 - 170,678,054 (+)EnsemblGRCm38mm10GRCm38
Cytogenetic MapXF5NCBI
Asmt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81221,418,477 - 21,423,336 (-)NCBIGRCr8
mRatBN7.21216,304,719 - 16,309,568 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1216,304,719 - 16,309,568 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1217,121,663 - 17,126,630 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01217,745,387 - 17,750,355 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01216,808,300 - 16,813,148 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01218,521,383 - 18,527,036 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,521,401 - 18,526,250 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,506,337 - 20,511,600 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41216,811,892 - 16,817,186 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11216,841,819 - 16,847,116 (-)NCBI
Celera1218,054,424 - 18,059,273 (-)NCBICelera
Cytogenetic Map12q11NCBI
Asmt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554991,131,588 - 1,152,802 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554991,131,637 - 1,151,861 (+)NCBIChiLan1.0ChiLan1.0
ASMT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X1,498,204 - 1,540,311 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1-v2Y45,410,535 - 45,444,147 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1Y1,514,466 - 1,544,183 (+)NCBINHGRI_mPanPan1
NHGRI_mPanPan1X1,513,326 - 1,543,959 (+)NCBINHGRI_mPanPan1
PanPan1.1X1,737,699 - 1,772,983 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX1,749,371 - 1,772,916 (+)Ensemblpanpan1.1panPan2
ASMT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X1,012,952 - 1,025,684 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX1,012,961 - 1,025,263 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX957,221 - 969,532 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X927,859 - 940,066 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX927,859 - 940,057 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X919,275 - 931,589 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X936,207 - 948,529 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X972,568 - 984,887 (+)NCBIUU_Cfam_GSD_1.0
Asmt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404953666,394 - 669,387 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366443,707,365 - 3,708,601 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103232876
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X1,838 - 12,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660561,759,444 - 1,802,665 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asmt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624834747,233 - 757,071 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system nervous system reproductive system
High
Medium
Low 1
Below cutoff 2 3 4 1

Sequence


Protein Sequences
Protein RefSeqs XP_020937045 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937046 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000048230
  ENSSSCP00000048230.1
  ENSSSCP00040023487.1
Protein Domains
Acetylserotonin O-methyltransferase dimerisation   O-methyltransferase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032659 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00040042185 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000057859 ENTREZGENE
  ENSSSCT00000057859.3 UniProtKB/TrEMBL
  ENSSSCT00040056438.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
InterPro ASMT_dimerisation UniProtKB/TrEMBL
  COMT-like UniProtKB/TrEMBL
  O_MeTrfase_dom UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene LOC110258194 ENTREZGENE
PANTHER O-METHYLTRANSFERASE CICE UniProtKB/TrEMBL
  PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED UniProtKB/TrEMBL
Pfam Dimerisation2 UniProtKB/TrEMBL
  Methyltransf_2 UniProtKB/TrEMBL
PIRSF O-mtase UniProtKB/TrEMBL
PROSITE SAM_OMT_II UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF53335 UniProtKB/TrEMBL
UniProt A0A287AVT1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1EM52 ENTREZGENE, UniProtKB/TrEMBL