FAM186B (family with sequence similarity 186 member B) - Rat Genome Database

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Gene: FAM186B (family with sequence similarity 186 member B) Sus scrofa
Analyze
Symbol: FAM186B
Name: family with sequence similarity 186 member B
RGD ID: 13984496
Description: ASSOCIATED WITH genetic disease (ortholog); nephronophthisis (ortholog); FOUND IN protein-containing complex (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein FAM186B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,541,865 - 15,559,720 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,542,001 - 15,570,658 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,941,864 - 15,950,612 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Genomics

Comparative Map Data
FAM186B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,541,865 - 15,559,720 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,542,001 - 15,570,658 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,941,864 - 15,950,612 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FAM186B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,582,873 - 49,622,758 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,582,885 - 49,605,639 (-)EnsemblGRCh38hg38GRCh38
GRCh371249,976,656 - 49,999,422 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,267,555 - 48,285,621 (-)NCBINCBI36Build 36hg18NCBI36
Celera1248,771,118 - 48,793,893 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,007,510 - 47,030,285 (-)NCBIHuRef
CHM1_11249,942,895 - 49,965,669 (-)NCBICHM1_1
T2T-CHM13v2.01249,545,133 - 49,585,767 (-)NCBIT2T-CHM13v2.0
Fam186b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,168,899 - 99,199,656 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,168,899 - 99,193,769 (-)EnsemblGRCm39 Ensembl
GRCm381599,271,018 - 99,301,775 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,271,018 - 99,295,888 (-)EnsemblGRCm38mm10GRCm38
MGSCv371599,101,449 - 99,117,611 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,099,052 - 99,115,214 (-)NCBIMGSCv36mm8
Celera15101,427,107 - 101,443,547 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.11NCBI
Fam186b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,287,686 - 132,303,188 (-)NCBIGRCr8
mRatBN7.27130,408,830 - 130,424,261 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,408,830 - 130,424,261 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,213,660 - 132,229,097 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,439,238 - 134,454,675 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,351,748 - 134,367,185 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07140,935,645 - 140,951,071 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,935,645 - 140,951,071 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,439,999 - 115,455,425 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,027,522 - 138,042,782 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7126,891,506 - 126,906,937 (-)NCBICelera
Cytogenetic Map7q36NCBI
Fam186b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547195,257 - 221,983 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955547198,336 - 232,031 (-)NCBIChiLan1.0ChiLan1.0
FAM186B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,569,199 - 44,608,082 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,562,296 - 44,612,651 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01239,146,430 - 39,169,472 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11240,037,593 - 40,066,084 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,037,593 - 40,058,640 (+)Ensemblpanpan1.1panPan2
FAM186B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,045,918 - 5,062,002 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,046,071 - 5,059,000 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,196,424 - 41,211,970 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0275,095,659 - 5,111,002 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl275,095,387 - 5,110,998 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,061,552 - 5,077,097 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,051,205 - 5,066,736 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,589,867 - 41,605,517 (-)NCBIUU_Cfam_GSD_1.0
Fam186b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,833,502 - 65,861,822 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,303,201 - 7,331,157 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,306,318 - 7,331,207 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM186B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,828,947 - 45,850,899 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1145,843,901 - 45,850,606 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037200,274,510 - 200,293,765 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam186b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248162,641,679 - 2,657,740 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FAM186B
850 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 2 3 1 22 2
Below cutoff 6 2 4 2 1 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000000218   ⟹   ENSSSCP00000000216
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl515,541,865 - 15,559,720 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000066441   ⟹   ENSSSCP00000060372
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl515,543,023 - 15,559,720 (-)Ensembl
RefSeq Acc Id: XM_021091213   ⟹   XP_020946872
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1515,542,001 - 15,570,658 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020946872 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000000216.4
  ENSSSCP00000060372.1
  ENSSSCP00025045838.1
  ENSSSCP00035039820.1
  ENSSSCP00045009488.1
Reference Protein Sequences
RefSeq Acc Id: XP_020946872   ⟸   XM_021091213
- UniProtKB: A0A8D1KSE7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000060372   ⟸   ENSSSCT00000066441
RefSeq Acc Id: ENSSSCP00000000216   ⟸   ENSSSCT00000000218
Protein Domains
FAM186A/B C-terminal   FAM186A/B N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000205 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00025075042 UniProtKB/TrEMBL
  ENSSSCG00035070169 UniProtKB/TrEMBL
  ENSSSCG00045008168 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000218.4 UniProtKB/TrEMBL
  ENSSSCT00000066441.1 UniProtKB/TrEMBL
  ENSSSCT00025103439.1 UniProtKB/TrEMBL
  ENSSSCT00035094773.1 UniProtKB/TrEMBL
  ENSSSCT00045013718.1 UniProtKB/TrEMBL
InterPro FAM186A_B_C UniProtKB/TrEMBL
  FAM186A_B_N UniProtKB/TrEMBL
NCBI Gene FAM186B ENTREZGENE
PANTHER GLUTENIN, HIGH MOLECULAR WEIGHT SUBUNIT PW212-RELATED PROTEIN UniProtKB/TrEMBL
  PROTEIN FAM186B UniProtKB/TrEMBL
Pfam FAM186A-B_C UniProtKB/TrEMBL
  FAM186A-B_N UniProtKB/TrEMBL
UniProt A0A5G2QQ07_PIG UniProtKB/TrEMBL
  A0A8D1KSE7 ENTREZGENE, UniProtKB/TrEMBL
  F1SHB0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87941 ENTREZGENE