ANKH (ANKH inorganic pyrophosphate transport regulator) - Rat Genome Database

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Gene: ANKH (ANKH inorganic pyrophosphate transport regulator) Sus scrofa
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Symbol: ANKH
Name: ANKH inorganic pyrophosphate transport regulator
RGD ID: 13983954
Description: ENCODES a protein that exhibits ATP transmembrane transporter activity (inferred); inorganic diphosphate transmembrane transporter activity (inferred); phosphate transmembrane transporter activity (inferred); INVOLVED IN ATP export; regulation of bone mineralization (ortholog); ASSOCIATED WITH ankylosis (ortholog); arthritis (ortholog); autosomal dominant craniometaphyseal dysplasia (ortholog); FOUND IN extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ankylosis, progressive homolog; progressive ankylosis protein homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl164,105,165 - 4,271,170 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1164,095,582 - 4,271,073 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,444,997 - 4,610,979 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
extracellular region  (IEA,ISO)
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:24286344   PMID:30032202  


Genomics

Comparative Map Data
ANKH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl164,105,165 - 4,271,170 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1164,095,582 - 4,271,073 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,444,997 - 4,610,979 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANKH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38514,704,800 - 14,871,778 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl514,704,800 - 14,871,778 (-)EnsemblGRCh38hg38GRCh38
GRCh37514,704,909 - 14,871,887 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36514,762,019 - 14,924,876 (-)NCBINCBI36Build 36hg18NCBI36
Build 34514,762,018 - 14,924,876NCBI
Celera514,728,867 - 14,895,594 (-)NCBICelera
Cytogenetic Map5p15.2NCBI
HuRef514,677,712 - 14,844,731 (-)NCBIHuRef
CHM1_1514,704,654 - 14,871,772 (-)NCBICHM1_1
T2T-CHM13v2.0514,644,272 - 14,811,218 (-)NCBIT2T-CHM13v2.0
Ank
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391527,466,763 - 27,594,995 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1527,466,763 - 27,594,995 (+)EnsemblGRCm39 Ensembl
GRCm381527,466,677 - 27,594,909 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1527,466,677 - 27,594,909 (+)EnsemblGRCm38mm10GRCm38
MGSCv371527,396,432 - 27,524,664 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361527,411,402 - 27,539,630 (+)NCBIMGSCv36mm8
Celera1528,188,363 - 28,342,822 (+)NCBICelera
Cytogenetic Map15B1NCBI
cM Map1510.23NCBI
Ankh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8279,883,350 - 80,011,222 (+)NCBIGRCr8
mRatBN7.2278,153,027 - 78,280,181 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,153,026 - 78,280,187 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx285,240,253 - 85,367,690 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0283,361,989 - 83,489,422 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0278,394,033 - 78,521,764 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0280,131,563 - 80,256,948 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,131,563 - 80,256,954 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0299,796,579 - 99,921,964 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4279,289,427 - 79,418,518 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1279,234,387 - 79,363,480 (+)NCBI
Celera273,782,876 - 73,934,310 (+)NCBICelera
Cytogenetic Map2q22NCBI
Ankh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554263,992,671 - 4,130,754 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554263,992,671 - 4,130,754 (-)NCBIChiLan1.0ChiLan1.0
ANKH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2414,944,516 - 15,105,199 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1513,098,133 - 13,258,900 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0515,014,019 - 15,175,467 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1514,849,497 - 15,015,206 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl514,855,914 - 14,917,729 (-)Ensemblpanpan1.1panPan2
ANKH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1488,149,250 - 88,263,926 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl488,149,257 - 88,272,464 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha487,670,608 - 87,785,793 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0488,877,936 - 88,993,145 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl488,877,991 - 88,999,454 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1488,304,136 - 88,419,117 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0488,546,753 - 88,661,820 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0489,403,928 - 89,519,108 (+)NCBIUU_Cfam_GSD_1.0
Ankh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213232,927,281 - 233,060,862 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366651,520,800 - 1,653,816 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366651,520,800 - 1,654,388 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1414,401,681 - 14,559,342 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl414,408,116 - 14,559,454 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606413,973,098 - 14,126,427 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ankh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475111,716,369 - 11,847,758 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475111,716,369 - 11,847,726 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ANKH
8101 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000018271   ⟹   ENSSSCP00000017779
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl164,105,165 - 4,271,045 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000073723   ⟹   ENSSSCP00000063913
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl164,105,167 - 4,271,170 (-)Ensembl
RefSeq Acc Id: XM_003359727   ⟹   XP_003359775
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1164,095,582 - 4,271,073 (-)NCBI
Sequence:
RefSeq Acc Id: XP_003359775   ⟸   XM_003359727
- UniProtKB: F1SRN1 (UniProtKB/TrEMBL),   A0A4X1TLB0 (UniProtKB/TrEMBL),   A0A480XL82 (UniProtKB/TrEMBL),   A0A8D2BSM7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000063913   ⟸   ENSSSCT00000073723
Ensembl Acc Id: ENSSSCP00000017779   ⟸   ENSSSCT00000018271


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016784 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025031315 UniProtKB/TrEMBL
  ENSSSCG00030045654 UniProtKB/TrEMBL
  ENSSSCG00035026859 UniProtKB/TrEMBL
  ENSSSCG00045034125 UniProtKB/TrEMBL
  ENSSSCG00055029807 UniProtKB/TrEMBL
  ENSSSCG00060070208 UniProtKB/TrEMBL
  ENSSSCG00065073523 UniProtKB/TrEMBL
  ENSSSCG00070011005 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018271 ENTREZGENE
  ENSSSCT00000018271.4 UniProtKB/TrEMBL
  ENSSSCT00000073723.2 UniProtKB/TrEMBL
  ENSSSCT00025042713.1 UniProtKB/TrEMBL
  ENSSSCT00025042838.1 UniProtKB/TrEMBL
  ENSSSCT00030063723.1 UniProtKB/TrEMBL
  ENSSSCT00030063747.1 UniProtKB/TrEMBL
  ENSSSCT00035035459.1 UniProtKB/TrEMBL
  ENSSSCT00035035463.1 UniProtKB/TrEMBL
  ENSSSCT00045058360.1 UniProtKB/TrEMBL
  ENSSSCT00045058448.1 UniProtKB/TrEMBL
  ENSSSCT00055059260.1 UniProtKB/TrEMBL
  ENSSSCT00055059279.1 UniProtKB/TrEMBL
  ENSSSCT00060095811.1 UniProtKB/TrEMBL
  ENSSSCT00060095826.1 UniProtKB/TrEMBL
  ENSSSCT00065101199.1 UniProtKB/TrEMBL
  ENSSSCT00065101204.1 UniProtKB/TrEMBL
  ENSSSCT00070021393.1 UniProtKB/TrEMBL
  ENSSSCT00070021405.1 UniProtKB/TrEMBL
InterPro ANKH UniProtKB/TrEMBL
KEGG Report ssc:100624458 UniProtKB/TrEMBL
NCBI Gene ANKH ENTREZGENE
PANTHER PROGRESSIVE ANKYLOSIS PROTEIN HOMOLOG UniProtKB/TrEMBL
  PTHR28384 UniProtKB/TrEMBL
Pfam ANKH UniProtKB/TrEMBL
UniProt A0A480XL82 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TLB0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0ZEL7_PIG UniProtKB/TrEMBL
  A0A8D1UEF2_PIG UniProtKB/TrEMBL
  A0A8D2BSM7 ENTREZGENE, UniProtKB/TrEMBL
  F1SRN1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A5G2QPA5 UniProtKB/TrEMBL
VGNC ID VGNC:85315 ENTREZGENE