GABRD (gamma-aminobutyric acid type A receptor subunit delta) - Rat Genome Database

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Gene: GABRD (gamma-aminobutyric acid type A receptor subunit delta) Sus scrofa
Analyze
Symbol: GABRD
Name: gamma-aminobutyric acid type A receptor subunit delta
RGD ID: 13979116
Description: ENCODES a protein that exhibits GABA-A receptor activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); chromosome 1p36 deletion syndrome (ortholog); congenital myasthenic syndrome 8 (ortholog); FOUND IN GABA-A receptor complex (ortholog); GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: gamma-aminobutyric acid (GABA) A receptor delta subunit; gamma-aminobutyric acid receptor subunit delta; gamma-aminobutyric acid type A receptor delta subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl664,049,675 - 64,059,640 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1664,049,665 - 64,059,644 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,561,062 - 58,563,060 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GABRD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl664,049,675 - 64,059,640 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1664,049,665 - 64,059,644 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,561,062 - 58,563,060 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GABRD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812,019,345 - 2,030,758 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12,019,329 - 2,030,758 (+)EnsemblGRCh38hg38GRCh38
GRCh3711,950,784 - 1,962,197 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,940,703 - 1,952,050 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411,983,004 - 1,994,352NCBI
Celera1630,843 - 641,887 (-)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef11,233,788 - 1,239,603 (+)NCBIHuRef
CHM1_111,937,892 - 1,949,316 (+)NCBICHM1_1
T2T-CHM13v2.011,454,897 - 1,466,310 (+)NCBIT2T-CHM13v2.0
Gabrd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,469,437 - 155,482,528 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,469,437 - 155,482,569 (-)EnsemblGRCm39 Ensembl
GRCm384155,384,979 - 155,398,098 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,384,980 - 155,398,112 (-)EnsemblGRCm38mm10GRCm38
MGSCv374154,759,088 - 154,772,178 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364154,228,780 - 154,241,862 (-)NCBIMGSCv36mm8
Celera4157,658,925 - 157,672,022 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map486.17NCBI
Gabrd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,240,813 - 171,252,709 (-)NCBIGRCr8
mRatBN7.25165,958,508 - 165,970,407 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5165,958,484 - 165,970,411 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5168,663,711 - 168,675,590 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,485,123 - 170,497,002 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,447,654 - 170,459,533 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05172,797,478 - 172,809,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5172,797,450 - 172,809,353 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05176,255,724 - 176,267,620 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,203,064 - 172,214,960 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15172,213,559 - 172,225,455 (-)NCBI
Celera5164,160,929 - 164,172,825 (-)NCBICelera
Cytogenetic Map5q36NCBI
Gabrd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,035,330 - 9,039,557 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554869,035,330 - 9,039,553 (-)NCBIChiLan1.0ChiLan1.0
GABRD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,238,362 - 226,249,814 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11224,896,964 - 224,908,423 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01731,714 - 743,165 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111,883,955 - 1,895,102 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,883,955 - 1,895,102 (+)Ensemblpanpan1.1panPan2
GABRD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,984,786 - 56,994,790 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,984,913 - 56,994,358 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha557,061,831 - 57,077,443 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0557,188,326 - 57,203,524 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl557,188,279 - 57,198,308 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1557,178,812 - 57,194,421 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0557,071,329 - 57,086,939 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0557,461,155 - 57,476,777 (+)NCBIUU_Cfam_GSD_1.0
Gabrd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505828,059,911 - 28,065,511 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367371,400,395 - 1,406,119 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367371,400,437 - 1,405,885 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABRD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120129,530,049 - 129,541,437 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20129,529,108 - 129,541,580 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605433,917,754 - 33,929,160 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabrd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248187,856,797 - 7,864,540 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248187,856,797 - 7,864,552 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GABRD
102 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system nervous system
High
Medium 4
Low 3 19
Below cutoff 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000037194   ⟹   ENSSSCP00000046186
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl664,049,705 - 64,059,640 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000079168   ⟹   ENSSSCP00000072379
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl664,049,675 - 64,059,639 (+)Ensembl
RefSeq Acc Id: XM_021095199   ⟹   XP_020950858
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1664,049,665 - 64,059,644 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020950858   ⟸   XM_021095199
- UniProtKB: A0A287AQK5 (UniProtKB/TrEMBL),   A0A4X1WA84 (UniProtKB/TrEMBL),   A0A8D1DI90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000072379   ⟸   ENSSSCT00000079168
RefSeq Acc Id: ENSSSCP00000046186   ⟸   ENSSSCT00000037194
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000035018 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025055048 UniProtKB/TrEMBL
  ENSSSCG00030014292 UniProtKB/TrEMBL
  ENSSSCG00035057335 UniProtKB/TrEMBL
  ENSSSCG00040013319 UniProtKB/TrEMBL
  ENSSSCG00045023189 UniProtKB/TrEMBL
  ENSSSCG00050007958 UniProtKB/TrEMBL
  ENSSSCG00060016671 UniProtKB/TrEMBL
  ENSSSCG00065077894 UniProtKB/TrEMBL
  ENSSSCG00070029625 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000037194 ENTREZGENE
  ENSSSCT00000037194.2 UniProtKB/TrEMBL
  ENSSSCT00000079168.2 UniProtKB/TrEMBL
  ENSSSCT00025075292.1 UniProtKB/TrEMBL
  ENSSSCT00030019653.1 UniProtKB/TrEMBL
  ENSSSCT00030019672.1 UniProtKB/TrEMBL
  ENSSSCT00035076677.1 UniProtKB/TrEMBL
  ENSSSCT00035076682.1 UniProtKB/TrEMBL
  ENSSSCT00040017692.1 UniProtKB/TrEMBL
  ENSSSCT00040017715.1 UniProtKB/TrEMBL
  ENSSSCT00045039657.1 UniProtKB/TrEMBL
  ENSSSCT00050010853.1 UniProtKB/TrEMBL
  ENSSSCT00060022248.1 UniProtKB/TrEMBL
  ENSSSCT00060022258.1 UniProtKB/TrEMBL
  ENSSSCT00065107784.1 UniProtKB/TrEMBL
  ENSSSCT00070059550.1 UniProtKB/TrEMBL
  ENSSSCT00070059551.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/TrEMBL
InterPro GABAA/Glycine_rcpt UniProtKB/TrEMBL
  GABAAd_rcpt UniProtKB/TrEMBL
  Neur_chan_lig-bd UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/TrEMBL
  Neur_channel UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/TrEMBL
NCBI Gene GABRD ENTREZGENE
PANTHER PTHR18945 UniProtKB/TrEMBL
  PTHR18945:SF34 UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/TrEMBL
PRINTS GABAARDELTA UniProtKB/TrEMBL
  GABAARECEPTR UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/TrEMBL
  SSF90112 UniProtKB/TrEMBL
UniProt A0A287AQK5 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1W8D7_PIG UniProtKB/TrEMBL
  A0A4X1WA84 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2R577_PIG UniProtKB/TrEMBL
  A0A8D0VN30_PIG UniProtKB/TrEMBL
  A0A8D1AB15_PIG UniProtKB/TrEMBL
  A0A8D1DI90 ENTREZGENE, UniProtKB/TrEMBL
  Q5CB40_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88309 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-25 GABRD  gamma-aminobutyric acid type A receptor subunit delta  GABRD  gamma-aminobutyric acid type A receptor delta subunit  Symbol and/or name change 5135510 APPROVED