NOX3 (NADPH oxidase 3) - Rat Genome Database

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Gene: NOX3 (NADPH oxidase 3) Sus scrofa
Analyze
Symbol: NOX3
Name: NADPH oxidase 3
RGD ID: 13978504
Description: ENCODES a protein that exhibits heme binding (inferred); oxidoreductase activity (inferred); superoxide-generating NAD(P)H oxidase activity (inferred); INVOLVED IN detection of gravity (ortholog); otolith development (ortholog); response to gravity (ortholog); PARTICIPATES IN thyroid hormone biosynthetic pathway; ASSOCIATED WITH chromosome 6q24-q25 deletion syndrome (ortholog); genetic disease (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); NADPH oxidase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl111,445,956 - 11,501,979 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1111,443,681 - 11,501,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
membrane  (IEA)
NADPH oxidase complex  (IBA,IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NOX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl111,445,956 - 11,501,979 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1111,443,681 - 11,501,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NOX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386155,395,368 - 155,455,839 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6155,395,368 - 155,455,839 (-)EnsemblGRCh38hg38GRCh38
GRCh376155,716,502 - 155,776,973 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366155,758,194 - 155,818,729 (-)NCBINCBI36Build 36hg18NCBI36
Build 346155,808,616 - 155,869,150NCBI
Celera6156,450,814 - 156,511,369 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6153,278,816 - 153,339,381 (-)NCBIHuRef
CHM1_16155,978,832 - 156,039,365 (-)NCBICHM1_1
T2T-CHM13v2.06156,597,411 - 156,657,886 (-)NCBIT2T-CHM13v2.0
Nox3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39173,685,515 - 3,746,536 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl173,685,515 - 3,746,536 (-)EnsemblGRCm39 Ensembl
GRCm38173,635,240 - 3,696,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl173,635,240 - 3,696,261 (-)EnsemblGRCm38mm10GRCm38
MGSCv37173,635,240 - 3,696,261 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36173,591,722 - 3,652,743 (-)NCBIMGSCv36mm8
Celera174,177,588 - 4,238,207 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map172.05NCBI
Nox3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8146,643,277 - 46,708,109 (-)NCBIGRCr8
mRatBN7.2144,238,012 - 44,302,851 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl144,236,992 - 44,302,851 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx144,778,955 - 44,843,788 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0150,766,188 - 50,831,023 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0144,854,449 - 44,919,295 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0144,550,994 - 44,615,760 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl144,550,994 - 44,615,760 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0145,881,398 - 45,946,253 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4138,641,566 - 38,707,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1138,644,510 - 38,710,675 (-)NCBI
Celera139,871,599 - 39,935,812 (-)NCBICelera
Cytogenetic Map1q11NCBI
Nox3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554396,764,693 - 6,820,278 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554396,764,693 - 6,820,278 (+)NCBIChiLan1.0ChiLan1.0
NOX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25175,416,786 - 175,477,155 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16173,308,307 - 173,368,658 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06153,210,190 - 153,270,955 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16159,174,261 - 159,234,642 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6159,174,261 - 159,234,642 (-)Ensemblpanpan1.1panPan2
NOX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1145,129,112 - 45,186,510 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl145,128,958 - 45,186,510 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha145,966,130 - 46,023,558 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0145,312,920 - 45,370,432 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl145,309,796 - 45,370,432 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1145,181,678 - 45,239,667 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0145,051,482 - 45,109,473 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0145,607,812 - 45,665,301 (-)NCBIUU_Cfam_GSD_1.0
Nox3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946140,316,169 - 140,371,377 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364897,569,620 - 7,623,369 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364897,568,162 - 7,623,370 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11382,972,005 - 83,033,457 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1382,970,184 - 83,032,974 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604055,340,628 - 55,441,413 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nox3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247852,893,559 - 2,954,793 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247852,869,024 - 2,955,039 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NOX3
1111 total Variants

Expression


Sequence


RefSeq Acc Id: ENSSSCT00000004497   ⟹   ENSSSCP00000004395
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl111,445,956 - 11,501,979 (+)Ensembl
RefSeq Acc Id: XM_021086590   ⟹   XP_020942249
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1111,443,681 - 11,501,140 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020942249 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000004395
  ENSSSCP00000004395.3
  ENSSSCP00005008771.1
  ENSSSCP00070044890.1
RefSeq Acc Id: XP_020942249   ⟸   XM_021086590
- UniProtKB: A0A4X1VUK8 (UniProtKB/TrEMBL),   A0A8D0IHI8 (UniProtKB/TrEMBL),   F1SB25 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000004395   ⟸   ENSSSCT00000004497
Protein Domains
FAD-binding FR-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004068 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005009522 UniProtKB/TrEMBL
  ENSSSCG00070026441 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004497 ENTREZGENE
  ENSSSCT00000004497.4 UniProtKB/TrEMBL
  ENSSSCT00005014691.1 UniProtKB/TrEMBL
  ENSSSCT00070052991.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.80 UniProtKB/TrEMBL
  Translation factors UniProtKB/TrEMBL
InterPro Cyt_b245_heavy_chain UniProtKB/TrEMBL
  FAD-bd_8 UniProtKB/TrEMBL
  FAD-bd_FR_type UniProtKB/TrEMBL
  Fe3_Rdtase_TM_dom UniProtKB/TrEMBL
  Fe_red_NAD-bd_6 UniProtKB/TrEMBL
  FNR_nucleotide-bd UniProtKB/TrEMBL
  Riboflavin_synthase-like_b-brl UniProtKB/TrEMBL
NCBI Gene NOX3 ENTREZGENE
PANTHER NADPH OXIDASE UniProtKB/TrEMBL
  PTHR11972:SF12 UniProtKB/TrEMBL
Pfam FAD_binding_8 UniProtKB/TrEMBL
  Ferric_reduct UniProtKB/TrEMBL
  NAD_binding_6 UniProtKB/TrEMBL
PRINTS GP91PHOX UniProtKB/TrEMBL
PROSITE FAD_FR UniProtKB/TrEMBL
Superfamily-SCOP SSF52343 UniProtKB/TrEMBL
  SSF63380 UniProtKB/TrEMBL
UniProt A0A4X1VUK8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IHI8 ENTREZGENE, UniProtKB/TrEMBL
  F1SB25 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:90830 ENTREZGENE