EGR2 (early growth response 2) - Rat Genome Database

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Gene: EGR2 (early growth response 2) Sus scrofa
Analyze
Symbol: EGR2
Name: early growth response 2
RGD ID: 13977482
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN aorta development (ortholog); brain segmentation (ortholog); cellular response to organic substance (ortholog); PARTICIPATES IN interleukin-4 signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease type 1 (ortholog); FOUND IN cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 SUMO-protein ligase EGR2; E3 SUMO-protein transferase ERG2; early growth response protein 2; EGR-2; KROX20
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1466,284,577 - 66,291,306 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11466,280,665 - 66,291,308 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21471,516,963 - 71,523,663 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q23-q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
EGR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1466,284,577 - 66,291,306 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11466,280,665 - 66,291,308 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21471,516,963 - 71,523,663 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q23-q25NCBI
EGR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1062,811,996 - 62,919,900 (-)EnsemblGRCh38hg38GRCh38
GRCh381062,811,996 - 62,819,167 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371064,571,756 - 64,578,927 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361064,241,763 - 64,246,133 (-)NCBINCBI36hg18NCBI36
Build 341064,241,762 - 64,246,133NCBI
Celera1057,839,025 - 57,846,195 (-)NCBI
Cytogenetic Map10q21.3NCBI
HuRef1058,563,537 - 58,570,711 (-)NCBIHuRef
CHM1_11064,853,748 - 64,860,918 (-)NCBICHM1_1
Egr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391067,370,334 - 67,383,354 (+)NCBIGRCm39mm39
GRCm39 Ensembl1067,371,305 - 67,378,018 (+)Ensembl
GRCm381067,534,469 - 67,542,188 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1067,535,475 - 67,542,188 (+)EnsemblGRCm38mm10GRCm38
MGSCv371067,000,617 - 67,004,936 (+)NCBIGRCm37mm9NCBIm37
MGSCv361066,933,235 - 66,937,545 (+)NCBImm8
Celera1068,629,352 - 68,633,671 (+)NCBICelera
Cytogenetic Map10B5.1NCBI
cM Map1034.96NCBI
Egr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22021,051,270 - 21,056,322 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2021,051,277 - 21,055,562 (-)Ensembl
Rnor_6.02022,452,170 - 22,461,018 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2022,454,463 - 22,459,025 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02024,551,935 - 24,556,227 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42021,883,885 - 21,888,177 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12021,897,685 - 21,901,977 (-)NCBI
Celera2022,412,625 - 22,416,917 (-)NCBICelera
Cytogenetic Map20p11NCBI
Egr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542516,055,748 - 16,060,048 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542516,055,748 - 16,068,429 (-)NCBIChiLan1.0ChiLan1.0
EGR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11061,648,364 - 61,652,846 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1061,648,364 - 61,652,846 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01059,320,073 - 59,326,869 (-)NCBIMhudiblu_PPA_v0panPan3
EGR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1414,705,384 - 14,810,130 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl414,706,600 - 14,709,497 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha414,923,311 - 15,027,362 (-)NCBI
ROS_Cfam_1.0414,969,904 - 15,074,026 (-)NCBI
UMICH_Zoey_3.1414,952,564 - 15,056,593 (-)NCBI
UNSW_CanFamBas_1.0415,077,597 - 15,181,626 (-)NCBI
UU_Cfam_GSD_1.0415,433,193 - 15,537,238 (-)NCBI
Egr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721366,381,281 - 66,388,026 (+)NCBI
SpeTri2.0NW_0049367531,958,250 - 1,962,640 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EGR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1968,472,640 - 68,479,612 (+)NCBI
ChlSab1.1 Ensembl968,475,102 - 68,479,595 (+)Ensembl
Vero_WHO_p1.0NW_02366604829,356,837 - 29,363,580 (+)NCBI
Egr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624791953,009 - 959,656 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2
Low 8 2 1 5 1 13 2 1
Below cutoff 2 2 2 1 8 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011190   ⟹   ENSSSCP00000010899
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1466,284,577 - 66,291,306 (-)Ensembl
RefSeq Acc Id: NM_001097488   ⟹   NP_001090957
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11466,285,809 - 66,288,650 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013983286   ⟹   XP_013838740
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11466,280,665 - 66,291,308 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001090957 (Get FASTA)   NCBI Sequence Viewer  
  XP_013838740 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A1XSY8 (Get FASTA)   NCBI Sequence Viewer  
  ABG49107 (Get FASTA)   NCBI Sequence Viewer  
  ABH09884 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013838740   ⟸   XM_013983286
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001090957   ⟸   NM_001097488
- UniProtKB: A1XSY8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010899   ⟸   ENSSSCT00000011190
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010224 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCG00015000015 UniProtKB/Swiss-Prot
  ENSSSCG00025076671 UniProtKB/Swiss-Prot
  ENSSSCG00030001532 UniProtKB/Swiss-Prot
  ENSSSCG00035074333 UniProtKB/Swiss-Prot
  ENSSSCG00040062455 UniProtKB/Swiss-Prot
  ENSSSCG00045032102 UniProtKB/Swiss-Prot
  ENSSSCG00050069806 UniProtKB/Swiss-Prot
  ENSSSCG00055014946 UniProtKB/Swiss-Prot
  ENSSSCG00060033163 UniProtKB/Swiss-Prot
  ENSSSCG00065069508 UniProtKB/Swiss-Prot
  ENSSSCG00070011768 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000010899 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCP00015000009 UniProtKB/Swiss-Prot
  ENSSSCP00025047689 UniProtKB/Swiss-Prot
  ENSSSCP00030000812 UniProtKB/Swiss-Prot
  ENSSSCP00035042903 UniProtKB/Swiss-Prot
  ENSSSCP00040037202 UniProtKB/Swiss-Prot
  ENSSSCP00045038266 UniProtKB/Swiss-Prot
  ENSSSCP00050040997 UniProtKB/Swiss-Prot
  ENSSSCP00055023524 UniProtKB/Swiss-Prot
  ENSSSCP00060019234 UniProtKB/Swiss-Prot
  ENSSSCP00065041762 UniProtKB/Swiss-Prot
  ENSSSCP00070018990 UniProtKB/TrEMBL
  ENSSSCP00070018996 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000011190 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCT00015000019 UniProtKB/Swiss-Prot
  ENSSSCT00025106300 UniProtKB/Swiss-Prot
  ENSSSCT00030001986 UniProtKB/Swiss-Prot
  ENSSSCT00035100914 UniProtKB/Swiss-Prot
  ENSSSCT00040085127 UniProtKB/Swiss-Prot
  ENSSSCT00045054904 UniProtKB/Swiss-Prot
  ENSSSCT00050095194 UniProtKB/Swiss-Prot
  ENSSSCT00055029550 UniProtKB/Swiss-Prot
  ENSSSCT00060044958 UniProtKB/Swiss-Prot
  ENSSSCT00065095440 UniProtKB/Swiss-Prot
  ENSSSCT00070022952 UniProtKB/TrEMBL
  ENSSSCT00070022960 UniProtKB/Swiss-Prot
InterPro EGR_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100038004 UniProtKB/Swiss-Prot
NCBI Gene EGR2 ENTREZGENE
Pfam DUF3446 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1TRR4_PIG UniProtKB/TrEMBL
  A1XSY8 ENTREZGENE
  A1Y1T9_PIG UniProtKB/TrEMBL
  EGR2_PIG UniProtKB/Swiss-Prot
VGNC ID VGNC:103939 ENTREZGENE