PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta) - Rat Genome Database

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Gene: PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta) Sus scrofa
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Symbol: PIK3CD
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
RGD ID: 13975579
Description: ENCODES a protein that exhibits kinase activity (inferred); phosphatidylinositol 3-kinase activity (inferred); phosphatidylinositol-3,4-bisphosphate 5-kinase activity (inferred); INVOLVED IN B cell activation (ortholog); B cell homeostasis (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; FasL mediated signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); Chlamydia pneumonia (ortholog); colorectal cancer (ortholog); FOUND IN phosphatidylinositol 3-kinase complex, class IA (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; phosphoinositide-3-kinase, catalytic, delta polypeptide
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl670,026,373 - 70,084,742 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1670,026,254 - 70,086,950 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2664,031,598 - 64,091,037 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
PIK3CD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl670,026,373 - 70,084,742 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1670,026,254 - 70,086,950 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2664,031,598 - 64,091,037 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3CD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819,627,258 - 9,729,114 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl19,629,889 - 9,729,114 (+)EnsemblGRCh38hg38GRCh38
GRCh3719,711,789 - 9,789,172 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619,634,377 - 9,711,759 (+)NCBINCBI36Build 36hg18NCBI36
Build 3419,646,068 - 9,723,240NCBI
Celera18,862,699 - 8,900,443 (+)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef18,867,937 - 8,945,277 (+)NCBIHuRef
CHM1_119,700,330 - 9,777,708 (+)NCBICHM1_1
T2T-CHM13v2.019,194,503 - 9,271,897 (+)NCBIT2T-CHM13v2.0
Pik3cd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394149,733,625 - 149,787,023 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4149,733,625 - 149,787,028 (-)EnsemblGRCm39 Ensembl
GRCm384149,649,168 - 149,702,566 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4149,649,168 - 149,702,571 (-)EnsemblGRCm38mm10GRCm38
MGSCv374149,023,277 - 149,075,738 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364148,492,968 - 148,542,489 (-)NCBIMGSCv36mm8
Celera4151,915,787 - 151,968,568 (-)NCBICelera
Cytogenetic Map4E2NCBI
Pik3cd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25160,094,952 - 160,142,962 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5160,094,952 - 160,120,930 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5162,811,574 - 162,837,548 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05164,630,975 - 164,656,844 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05164,587,341 - 164,613,203 (-)NCBIRnor_WKY
Rnor_6.05166,602,053 - 166,628,028 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,602,053 - 166,628,028 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05170,248,202 - 170,274,177 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45166,735,274 - 166,761,189 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15166,747,134 - 166,774,251 (-)NCBI
Celera5158,364,393 - 158,390,431 (-)NCBICelera
Cytogenetic Map5q36NCBI
Pik3cd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554863,813,923 - 3,838,119 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554863,813,923 - 3,837,563 (-)NCBIChiLan1.0ChiLan1.0
PIK3CD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.119,683,626 - 9,724,641 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl19,686,208 - 9,724,633 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v018,418,570 - 8,495,435 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PIK3CD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1562,884,596 - 62,936,882 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl562,909,009 - 62,935,971 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha562,900,181 - 62,953,014 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0563,111,143 - 63,163,978 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl563,093,394 - 63,164,766 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1563,132,926 - 63,185,725 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0562,972,335 - 63,025,149 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0563,376,064 - 63,428,899 (+)NCBIUU_Cfam_GSD_1.0
Pik3cd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505833,167,388 - 33,211,355 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366233,672,201 - 3,696,959 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3CD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120122,040,131 - 122,111,397 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20122,041,963 - 122,078,504 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605426,005,112 - 26,077,450 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pik3cd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248182,751,724 - 2,779,999 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248182,751,724 - 2,789,145 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 10 2 3 4 1 23 2 3 3
Below cutoff 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000003766   ⟹   ENSSSCP00000003679
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl670,026,373 - 70,099,244 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000032225   ⟹   ENSSSCP00000026488
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl670,026,373 - 70,084,742 (+)Ensembl
RefSeq Acc Id: XM_003127540   ⟹   XP_003127588
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1670,048,102 - 70,086,480 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005664977   ⟹   XP_005665034
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1670,026,284 - 70,086,480 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005664978   ⟹   XP_005665035
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1670,026,254 - 70,086,480 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013998954   ⟹   XP_013854408
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1670,026,305 - 70,086,950 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021095291   ⟹   XP_020950950
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1670,026,307 - 70,086,480 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021095292   ⟹   XP_020950951
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1670,026,305 - 70,086,950 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005665035   ⟸   XM_005664978
- Peptide Label: isoform X1
- UniProtKB: F1RIH5 (UniProtKB/TrEMBL),   A0A5K1UPW2 (UniProtKB/TrEMBL),   A0A8D0WQF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005665034   ⟸   XM_005664977
- Peptide Label: isoform X1
- UniProtKB: F1RIH5 (UniProtKB/TrEMBL),   A0A5K1UPW2 (UniProtKB/TrEMBL),   A0A8D0WQF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013854408   ⟸   XM_013998954
- Peptide Label: isoform X2
- UniProtKB: A0A8D1VQB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950951   ⟸   XM_021095292
- Peptide Label: isoform X2
- UniProtKB: A0A8D1VQB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950950   ⟸   XM_021095291
- Peptide Label: isoform X1
- UniProtKB: A0A5K1UPW2 (UniProtKB/TrEMBL),   A0A8D0WQF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003127588   ⟸   XM_003127540
- Peptide Label: isoform X1
- UniProtKB: F1RIH5 (UniProtKB/TrEMBL),   A0A5K1UPW2 (UniProtKB/TrEMBL),   A0A8D0WQF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000003679   ⟸   ENSSSCT00000003766
RefSeq Acc Id: ENSSSCP00000026488   ⟸   ENSSSCT00000032225

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000003395 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025071262 UniProtKB/TrEMBL
  ENSSSCG00030037900 UniProtKB/TrEMBL
  ENSSSCG00035061045 UniProtKB/TrEMBL
  ENSSSCG00040052220 UniProtKB/TrEMBL
  ENSSSCG00045001046 UniProtKB/TrEMBL
  ENSSSCG00050028758 UniProtKB/TrEMBL
  ENSSSCG00055027528 UniProtKB/TrEMBL
  ENSSSCG00060047907 UniProtKB/TrEMBL
  ENSSSCG00065010729 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000026488 ENTREZGENE
  ENSSSCP00000026488.2 UniProtKB/TrEMBL
  ENSSSCP00025043233.1 UniProtKB/TrEMBL
  ENSSSCP00025043415.1 UniProtKB/TrEMBL
  ENSSSCP00030024097.1 UniProtKB/TrEMBL
  ENSSSCP00030024105.1 UniProtKB/TrEMBL
  ENSSSCP00035033976.1 UniProtKB/TrEMBL
  ENSSSCP00035033983.1 UniProtKB/TrEMBL
  ENSSSCP00040030171.1 UniProtKB/TrEMBL
  ENSSSCP00040030292.1 UniProtKB/TrEMBL
  ENSSSCP00045000966.1 UniProtKB/TrEMBL
  ENSSSCP00045000983.1 UniProtKB/TrEMBL
  ENSSSCP00050016021.1 UniProtKB/TrEMBL
  ENSSSCP00050016026.1 UniProtKB/TrEMBL
  ENSSSCP00055043420.1 UniProtKB/TrEMBL
  ENSSSCP00055043506.1 UniProtKB/TrEMBL
  ENSSSCP00060027850.1 UniProtKB/TrEMBL
  ENSSSCP00060027852.1 UniProtKB/TrEMBL
  ENSSSCP00065005808.1 UniProtKB/TrEMBL
  ENSSSCP00065005810.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000032225 ENTREZGENE
  ENSSSCT00000032225.4 UniProtKB/TrEMBL
  ENSSSCT00025098306.1 UniProtKB/TrEMBL
  ENSSSCT00025098679.1 UniProtKB/TrEMBL
  ENSSSCT00030052828.1 UniProtKB/TrEMBL
  ENSSSCT00030052848.1 UniProtKB/TrEMBL
  ENSSSCT00035081991.1 UniProtKB/TrEMBL
  ENSSSCT00035082002.1 UniProtKB/TrEMBL
  ENSSSCT00040070832.1 UniProtKB/TrEMBL
  ENSSSCT00040071056.1 UniProtKB/TrEMBL
  ENSSSCT00045001590.1 UniProtKB/TrEMBL
  ENSSSCT00045001613.1 UniProtKB/TrEMBL
  ENSSSCT00050038694.1 UniProtKB/TrEMBL
  ENSSSCT00050038706.1 UniProtKB/TrEMBL
  ENSSSCT00055054439.1 UniProtKB/TrEMBL
  ENSSSCT00055054538.1 UniProtKB/TrEMBL
  ENSSSCT00060065049.1 UniProtKB/TrEMBL
  ENSSSCT00060065059.1 UniProtKB/TrEMBL
  ENSSSCT00065014262.1 UniProtKB/TrEMBL
  ENSSSCT00065014270.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1070.11 UniProtKB/TrEMBL
  1.25.40.70 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.10.20.770 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  PI3/4_kinase_cat_dom UniProtKB/TrEMBL
  PI3/4_kinase_cat_sf UniProtKB/TrEMBL
  PI3/4_kinase_CS UniProtKB/TrEMBL
  PI3K_accessory_sf UniProtKB/TrEMBL
  PI3K_adapt-bd_dom UniProtKB/TrEMBL
  PI3K_C2_dom UniProtKB/TrEMBL
  PI3K_Ras-bd_dom UniProtKB/TrEMBL
  PI3Kdelta_dom UniProtKB/TrEMBL
  PI_Kinase UniProtKB/TrEMBL
  PInositide-3_kin_accessory_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report ssc:100518131 UniProtKB/TrEMBL
NCBI Gene PIK3CD ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM UniProtKB/TrEMBL
  PTHR10048 UniProtKB/TrEMBL
Pfam PI3_PI4_kinase UniProtKB/TrEMBL
  PI3K_C2 UniProtKB/TrEMBL
  PI3K_p85B UniProtKB/TrEMBL
  PI3K_rbd UniProtKB/TrEMBL
  PI3Ka UniProtKB/TrEMBL
PROSITE PI3_4_KINASE_1 UniProtKB/TrEMBL
  PI3_4_KINASE_2 UniProtKB/TrEMBL
  PI3_4_KINASE_3 UniProtKB/TrEMBL
  PI3K_ABD UniProtKB/TrEMBL
  PI3K_C2 UniProtKB/TrEMBL
  PI3K_RBD UniProtKB/TrEMBL
  PIK_HELICAL UniProtKB/TrEMBL
SMART PI3K_C2 UniProtKB/TrEMBL
  PI3K_p85B UniProtKB/TrEMBL
  PI3K_rbd UniProtKB/TrEMBL
  PI3Ka UniProtKB/TrEMBL
  PI3Kc UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A5K1UPW2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WQF3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1VQB8 ENTREZGENE, UniProtKB/TrEMBL
  F1RIH5 ENTREZGENE
VGNC ID VGNC:91442 ENTREZGENE