SLC36A4 (solute carrier family 36 member 4) - Rat Genome Database

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Gene: SLC36A4 (solute carrier family 36 member 4) Sus scrofa
Analyze
Symbol: SLC36A4
Name: solute carrier family 36 member 4
RGD ID: 13975015
Description: ENCODES a protein that exhibits L-alanine transmembrane transporter activity (inferred); L-proline transmembrane transporter activity (inferred); L-tryptophan transmembrane transporter activity (inferred); INVOLVED IN L-alanine transport (inferred); proline transmembrane transport (inferred); proline transport (inferred); PARTICIPATES IN nicotinamide adenine dinucleotide metabolic pathway; ASSOCIATED WITH intellectual disability (ortholog); FOUND IN lysosomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proton-coupled amino acid transporter 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl925,639,387 - 25,689,028 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1925,639,370 - 25,689,177 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2928,983,529 - 29,033,251 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:28943389   PMID:30032202  


Genomics

Comparative Map Data
SLC36A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl925,639,387 - 25,689,028 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1925,639,370 - 25,689,177 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2928,983,529 - 29,033,251 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC36A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381193,144,174 - 93,197,991 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1193,144,174 - 93,197,991 (-)EnsemblGRCh38hg38GRCh38
GRCh371192,877,340 - 92,931,157 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361192,520,498 - 92,570,743 (-)NCBINCBI36Build 36hg18NCBI36
Build 341192,520,499 - 92,570,743NCBI
Celera1190,179,804 - 90,230,049 (-)NCBICelera
Cytogenetic Map11q21NCBI
HuRef1188,965,724 - 89,015,692 (-)NCBIHuRef
CHM1_11192,763,842 - 92,814,140 (-)NCBICHM1_1
T2T-CHM13v2.01193,066,962 - 93,120,802 (-)NCBIT2T-CHM13v2.0
Slc36a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39915,621,034 - 15,653,684 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl915,621,034 - 15,654,657 (+)EnsemblGRCm39 Ensembl
GRCm38915,709,738 - 15,742,388 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl915,709,738 - 15,743,361 (+)EnsemblGRCm38mm10GRCm38
MGSCv37915,514,213 - 15,543,233 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36915,460,162 - 15,489,182 (+)NCBIMGSCv36mm8
Celera912,988,023 - 13,017,043 (+)NCBICelera
Cytogenetic Map9A2NCBI
cM Map95.12NCBI
Slc36a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8820,801,256 - 20,834,046 (+)NCBIGRCr8
mRatBN7.2812,519,613 - 12,552,671 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl812,519,943 - 12,552,031 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx816,506,726 - 16,536,678 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0814,804,480 - 14,834,432 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0812,782,331 - 12,813,520 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0814,238,975 - 14,271,931 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl814,239,594 - 14,269,162 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0814,329,327 - 14,360,233 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4812,504,817 - 12,534,782 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1812,504,818 - 12,533,407 (+)NCBI
Celera813,985,685 - 14,015,651 (+)NCBICelera
Cytogenetic Map8q12NCBI
Slc36a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554141,236,141 - 1,285,610 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554141,236,179 - 1,286,680 (+)NCBIChiLan1.0ChiLan1.0
SLC36A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2994,008,249 - 94,062,806 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11195,097,192 - 95,150,608 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01188,164,083 - 88,218,610 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11191,662,625 - 91,880,929 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1191,663,479 - 91,713,388 (-)Ensemblpanpan1.1panPan2
SLC36A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1217,476,291 - 7,523,463 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl217,475,648 - 7,520,331 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha217,474,725 - 7,538,019 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0217,635,696 - 7,698,997 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl217,635,686 - 7,698,993 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1217,421,675 - 7,481,882 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0217,490,947 - 7,554,286 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0217,535,348 - 7,598,628 (+)NCBIUU_Cfam_GSD_1.0
Slc36a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494778,289,864 - 78,363,803 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366741,567,675 - 1,601,635 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366741,567,718 - 1,601,561 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC36A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1184,393,698 - 84,487,984 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl184,398,027 - 84,445,971 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604341,344,168 - 41,395,986 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc36a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473537,791,206 - 37,831,776 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473537,791,690 - 37,831,749 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC36A4
2235 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000023503   ⟹   ENSSSCP00000022788
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl925,639,387 - 25,689,028 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000078849   ⟹   ENSSSCP00000066780
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl925,639,388 - 25,689,001 (-)Ensembl
RefSeq Acc Id: XM_005667225   ⟹   XP_005667282
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1925,639,370 - 25,689,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979268   ⟹   XP_013834722
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1925,639,651 - 25,688,980 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021062637   ⟹   XP_020918296
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1925,639,651 - 25,683,262 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005667282   ⟸   XM_005667225
- Peptide Label: isoform X1
- UniProtKB: A0A8D1WH29 (UniProtKB/TrEMBL),   A0A480EJB7 (UniProtKB/TrEMBL),   A0A4X1TWC3 (UniProtKB/TrEMBL),   I3LFE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834722   ⟸   XM_013979268
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020918296   ⟸   XM_021062637
- Peptide Label: isoform X2
- UniProtKB: A0A8D1WHS5 (UniProtKB/TrEMBL),   A0A5G2QPX8 (UniProtKB/TrEMBL),   A0A4X1TWC3 (UniProtKB/TrEMBL),   I3LFE6 (UniProtKB/TrEMBL),   A0A8D0Q4R1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000066780   ⟸   ENSSSCT00000078849
Ensembl Acc Id: ENSSSCP00000022788   ⟸   ENSSSCT00000023503

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024933 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015076754 UniProtKB/TrEMBL
  ENSSSCG00025033410 UniProtKB/TrEMBL
  ENSSSCG00030064647 UniProtKB/TrEMBL
  ENSSSCG00035012620 UniProtKB/TrEMBL
  ENSSSCG00040063806 UniProtKB/TrEMBL
  ENSSSCG00045018599 UniProtKB/TrEMBL
  ENSSSCG00050016018 UniProtKB/TrEMBL
  ENSSSCG00055013509 UniProtKB/TrEMBL
  ENSSSCG00060067101 UniProtKB/TrEMBL
  ENSSSCG00065047955 UniProtKB/TrEMBL
  ENSSSCG00070012858 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000023503 ENTREZGENE
  ENSSSCT00000023503.3 UniProtKB/TrEMBL
  ENSSSCT00000078849 ENTREZGENE
  ENSSSCT00000078849.1 UniProtKB/TrEMBL
  ENSSSCT00015103593.1 UniProtKB/TrEMBL
  ENSSSCT00015103675.1 UniProtKB/TrEMBL
  ENSSSCT00025045459.1 UniProtKB/TrEMBL
  ENSSSCT00025045554.1 UniProtKB/TrEMBL
  ENSSSCT00030090340.1 UniProtKB/TrEMBL
  ENSSSCT00030090379.1 UniProtKB/TrEMBL
  ENSSSCT00035015917.1 UniProtKB/TrEMBL
  ENSSSCT00040087079.1 UniProtKB/TrEMBL
  ENSSSCT00040087205.1 UniProtKB/TrEMBL
  ENSSSCT00045031632.1 UniProtKB/TrEMBL
  ENSSSCT00045031756.1 UniProtKB/TrEMBL
  ENSSSCT00050021769.1 UniProtKB/TrEMBL
  ENSSSCT00050021789.1 UniProtKB/TrEMBL
  ENSSSCT00055026616.1 UniProtKB/TrEMBL
  ENSSSCT00055026695.1 UniProtKB/TrEMBL
  ENSSSCT00060091567.1 UniProtKB/TrEMBL
  ENSSSCT00060091601.1 UniProtKB/TrEMBL
  ENSSSCT00065065600.1 UniProtKB/TrEMBL
  ENSSSCT00065065612.1 UniProtKB/TrEMBL
  ENSSSCT00070025119.1 UniProtKB/TrEMBL
InterPro AA_transpt_TM UniProtKB/TrEMBL
KEGG Report ssc:100511947 UniProtKB/TrEMBL
NCBI Gene SLC36A4 ENTREZGENE
PANTHER AMINO ACID TRANSPORTER UniProtKB/TrEMBL
  PROTON-COUPLED AMINO ACID TRANSPORTER 4 UniProtKB/TrEMBL
Pfam Aa_trans UniProtKB/TrEMBL
UniProt A0A480EJB7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TWC3 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QPX8 ENTREZGENE
  A0A8D0Q4R1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WH29 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WHS5 ENTREZGENE, UniProtKB/TrEMBL
  I3LFE6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A5G2QPX8 UniProtKB/TrEMBL
VGNC ID VGNC:93091 ENTREZGENE