GJC2 (gap junction protein gamma 2) - Rat Genome Database
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Gene: GJC2 (gap junction protein gamma 2) Sus scrofa
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Symbol: GJC2
Name: gap junction protein gamma 2
RGD ID: 13973016
Description: ENCODES a protein that exhibits gap junction channel activity (ortholog); INVOLVED IN brain development (ortholog); cell-cell signaling (ortholog); negative regulation of G1/S transition of mitotic cell cycle (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); dystonia (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); FOUND IN gap junction (ortholog); myelin sheath (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: gap junction gamma-2 protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl251,258,207 - 51,267,966 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1251,257,623 - 51,267,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2253,844,201 - 53,854,379 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
GJC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl251,258,207 - 51,267,966 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1251,257,623 - 51,267,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2253,844,201 - 53,854,379 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GJC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1228,149,930 - 228,159,826 (+)EnsemblGRCh38hg38GRCh38
GRCh381228,149,930 - 228,159,826 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371228,337,631 - 228,347,527 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,404,176 - 226,414,150 (+)NCBINCBI36hg18NCBI36
Build 341224,644,287 - 224,654,260NCBI
Celera1201,527,795 - 201,537,768 (+)NCBI
Cytogenetic Map1q42.13NCBI
HuRef1198,852,444 - 198,862,502 (+)NCBIHuRef
CHM1_11229,609,739 - 229,619,848 (+)NCBICHM1_1
Gjc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,066,390 - 59,074,039 (-)NCBIGRCm39mm39
GRCm39 Ensembl1159,066,394 - 59,074,039 (-)Ensembl
GRCm381159,175,564 - 59,183,213 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,175,568 - 59,183,213 (-)EnsemblGRCm38mm10GRCm38
MGSCv371158,989,066 - 58,996,715 (-)NCBIGRCm37mm9NCBIm37
MGSCv361158,991,761 - 58,999,408 (-)NCBImm8
Celera1163,940,632 - 63,948,320 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1137.05NCBI
Gjc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21043,962,642 - 43,971,358 (-)NCBI
Rnor_6.0 Ensembl1045,526,745 - 45,534,570 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01045,526,740 - 45,535,520 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01045,282,830 - 45,291,628 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41045,480,937 - 45,488,651 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1043,225,920 - 43,233,731 (-)NCBICelera
Cytogenetic Map10q22NCBI
Gjc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955581291,537 - 294,752 (-)NCBIChiLan1.0ChiLan1.0
GJC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11208,762,974 - 208,772,229 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01203,551,556 - 203,561,702 (+)NCBIMhudiblu_PPA_v0panPan3
GJC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl14810,386 - 820,420 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.114810,388 - 819,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gjc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493686467,608 - 71,543 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GJC2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1251,568,664 - 1,579,279 (-)NCBI
ChlSab1.1 Ensembl251,569,427 - 1,570,752 (-)Ensembl
Gjc2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624937898,876 - 905,247 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium 11
Low 4 9 2
Below cutoff 5 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000015280   ⟹   ENSSSCP00000014874
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl251,258,207 - 51,267,964 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000069107   ⟹   ENSSSCP00000074037
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl251,258,825 - 51,267,966 (+)Ensembl
RefSeq Acc Id: XM_005661143   ⟹   XP_005661200
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1251,258,347 - 51,267,969 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005661145   ⟹   XP_005661202
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1251,257,623 - 51,267,969 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005661146   ⟹   XP_005661203
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1251,264,260 - 51,267,969 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005661200 (Get FASTA)   NCBI Sequence Viewer  
  XP_005661202 (Get FASTA)   NCBI Sequence Viewer  
  XP_005661203 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005661202   ⟸   XM_005661145
- Peptide Label: isoform X2
- UniProtKB: F1S5S0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005661200   ⟸   XM_005661143
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005661203   ⟸   XM_005661146
- Peptide Label: isoform X2
- UniProtKB: F1S5S0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000014874   ⟸   ENSSSCT00000015280
RefSeq Acc Id: ENSSSCP00000074037   ⟸   ENSSSCT00000069107
Protein Domains
CNX   Connexin_CCC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013989 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000014874 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000074037 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015280 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000069107 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.20.1440.80 UniProtKB/TrEMBL
InterPro Connexin UniProtKB/TrEMBL
  Connexin_CCC UniProtKB/TrEMBL
  Connexin_CS UniProtKB/TrEMBL
  Connexin_N UniProtKB/TrEMBL
  Connexin_N_sf UniProtKB/TrEMBL
NCBI Gene GJC2 ENTREZGENE
PANTHER PTHR11984 UniProtKB/TrEMBL
Pfam Connexin UniProtKB/TrEMBL
PRINTS CONNEXIN UniProtKB/TrEMBL
PROSITE CONNEXINS_1 UniProtKB/TrEMBL
  CONNEXINS_2 UniProtKB/TrEMBL
SMART CNX UniProtKB/TrEMBL
  Connexin_CCC UniProtKB/TrEMBL
UniProt F1S5S0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:88469 ENTREZGENE