LOC100525933 (transmembrane protease serine 11A) - Rat Genome Database

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Gene: LOC100525933 (transmembrane protease serine 11A) Sus scrofa
Analyze
Symbol: LOC100525933 (Ensembl: TMPRSS11A)
Name: transmembrane protease serine 11A (Ensembl:transmembrane serine protease 11A)
RGD ID: 13971632
Description: ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN extracellular region (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TMPRSS11A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl865,636,500 - 65,684,002 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1865,635,551 - 65,684,004 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2870,060,270 - 70,105,495 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LOC100525933
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl865,636,500 - 65,684,002 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1865,635,551 - 65,684,004 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2870,060,270 - 70,105,495 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMPRSS11A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38467,909,395 - 67,963,493 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl467,909,395 - 67,964,140 (-)EnsemblGRCh38hg38GRCh38
GRCh37468,775,113 - 68,829,211 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36468,458,614 - 68,511,827 (-)NCBINCBI36Build 36hg18NCBI36
Celera466,238,428 - 66,291,616 (-)NCBICelera
Cytogenetic Map4q13.2NCBI
HuRef464,689,116 - 64,742,288 (-)NCBIHuRef
CHM1_1468,813,094 - 68,866,308 (-)NCBICHM1_1
T2T-CHM13v2.0471,352,520 - 71,406,589 (-)NCBIT2T-CHM13v2.0
Tmprss11a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39586,558,269 - 86,617,034 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl586,558,269 - 86,616,849 (-)EnsemblGRCm39 Ensembl
GRCm38586,410,410 - 86,469,175 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl586,410,410 - 86,468,990 (-)EnsemblGRCm38mm10GRCm38
MGSCv37586,839,435 - 86,898,015 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36587,484,971 - 87,543,551 (-)NCBIMGSCv36mm8
Celera583,639,113 - 83,697,451 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.56NCBI
Tmprss11a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81421,961,342 - 22,020,088 (+)NCBIGRCr8
mRatBN7.21421,624,881 - 21,665,284 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1421,606,547 - 21,665,279 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01423,226,735 - 23,284,515 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1423,245,653 - 23,283,092 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01423,136,021 - 23,173,398 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1421,079,097 - 21,138,292 (+)NCBICelera
Cytogenetic Map14p21NCBI
TMPRSS11A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2361,948,484 - 61,984,297 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1462,158,564 - 62,194,333 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0456,087,123 - 56,139,951 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1462,481,403 - 62,533,929 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl462,481,403 - 62,533,929 (+)Ensemblpanpan1.1panPan2
TMPRSS11A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11358,412,487 - 58,484,166 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1358,432,305 - 58,482,573 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1358,349,009 - 58,384,157 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01359,128,326 - 59,158,878 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1359,127,611 - 59,177,930 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11358,771,278 - 58,806,522 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01358,266,629 - 58,317,564 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01359,272,292 - 59,307,463 (-)NCBIUU_Cfam_GSD_1.0
LOC101971520
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528517,973,627 - 18,025,045 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936582548,005 - 588,543 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936582550,285 - 588,538 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMPRSS11A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.171,005,831 - 1,046,469 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl71,006,205 - 1,046,428 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660661,085,894 - 1,148,646 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmprss11a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624761877,617 - 949,804 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624761877,313 - 951,663 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LOC100525933
917 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system reproductive system respiratory system
High
Medium 1 1 1
Low 1
Below cutoff 2 1 1 1 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000052889   ⟹   ENSSSCP00000054447
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl865,636,500 - 65,684,002 (-)Ensembl
RefSeq Acc Id: XM_013978753   ⟹   XP_013834207
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1865,635,551 - 65,684,004 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013834207   ⟸   XM_013978753
- UniProtKB: A0A4X1TDU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000054447   ⟸   ENSSSCT00000052889
Protein Domains
Peptidase S1   SEA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008927 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015038120 UniProtKB/TrEMBL
  ENSSSCG00025036388 UniProtKB/TrEMBL
  ENSSSCG00035021084 UniProtKB/TrEMBL
  ENSSSCG00040070624 UniProtKB/TrEMBL
  ENSSSCG00045001702 UniProtKB/TrEMBL
  ENSSSCG00050071562 UniProtKB/TrEMBL
  ENSSSCG00055021164 UniProtKB/TrEMBL
  ENSSSCG00060072107 UniProtKB/TrEMBL
  ENSSSCG00065050776 UniProtKB/TrEMBL
  ENSSSCG00070008597 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000052889 ENTREZGENE
  ENSSSCT00000052889.3 UniProtKB/TrEMBL
  ENSSSCT00015050733.1 UniProtKB/TrEMBL
  ENSSSCT00025049577.1 UniProtKB/TrEMBL
  ENSSSCT00035027464.1 UniProtKB/TrEMBL
  ENSSSCT00040097049.1 UniProtKB/TrEMBL
  ENSSSCT00045002694.1 UniProtKB/TrEMBL
  ENSSSCT00050097598.1 UniProtKB/TrEMBL
  ENSSSCT00055041568.1 UniProtKB/TrEMBL
  ENSSSCT00060098513.1 UniProtKB/TrEMBL
  ENSSSCT00065069551.1 UniProtKB/TrEMBL
  ENSSSCT00070016640.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
  3.30.70.960 UniProtKB/TrEMBL
InterPro Pept_S1A_HAT/DESC1 UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  SEA_dom UniProtKB/TrEMBL
  SEA_dom_sf UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
KEGG Report ssc:100525933 UniProtKB/TrEMBL
NCBI Gene LOC100525933 ENTREZGENE
PANTHER ACROSIN-RELATED UniProtKB/TrEMBL
  HYALIN UniProtKB/TrEMBL
  TRANSMEMBRANE SERINE PROTEASE 12 UniProtKB/TrEMBL
Pfam SEA UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PIRSF TMPRSS11ABCDE UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE SEA UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
  SSF82671 UniProtKB/TrEMBL
UniProt A0A287BEC5_PIG UniProtKB/TrEMBL
  A0A4X1TDU5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YZQ5_PIG UniProtKB/TrEMBL