TTYH3 (tweety family member 3) - Rat Genome Database

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Gene: TTYH3 (tweety family member 3) Sus scrofa
Analyze
Symbol: TTYH3
Name: tweety family member 3
RGD ID: 13970843
Description: ENCODES a protein that exhibits chloride channel activity (ortholog); volume-sensitive anion channel activity (ortholog); INVOLVED IN chloride transmembrane transport (inferred); chloride transport (inferred); L-glutamate transmembrane transport (inferred); ASSOCIATED WITH immunodeficiency 11A (ortholog); FOUND IN chloride channel complex (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein tweety homolog 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl31,826,293 - 1,853,493 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.131,826,284 - 1,853,522 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.232,173,619 - 2,201,179 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TTYH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl31,826,293 - 1,853,493 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.131,826,284 - 1,853,522 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.232,173,619 - 2,201,179 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTYH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3872,631,986 - 2,664,802 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl72,631,961 - 2,664,802 (+)EnsemblGRCh38hg38GRCh38
GRCh3772,671,620 - 2,704,436 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3672,638,129 - 2,670,962 (+)NCBINCBI36Build 36hg18NCBI36
Celera72,640,452 - 2,673,317 (+)NCBICelera
Cytogenetic Map7p22.3NCBI
HuRef72,589,841 - 2,622,726 (+)NCBIHuRef
CHM1_172,671,274 - 2,704,022 (+)NCBICHM1_1
T2T-CHM13v2.072,745,500 - 2,778,329 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v272,719,442 - 2,752,317 (+)NCBI
Ttyh3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395140,606,332 - 140,634,826 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5140,606,333 - 140,634,786 (-)EnsemblGRCm39 Ensembl
GRCm385140,620,577 - 140,649,071 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5140,620,578 - 140,649,031 (-)EnsemblGRCm38mm10GRCm38
MGSCv375141,096,532 - 141,124,985 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365140,873,114 - 140,901,498 (-)NCBIMGSCv36mm8
Celera5137,680,994 - 137,709,444 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map579.16NCBI
Ttyh3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81219,110,973 - 19,139,379 (+)NCBIGRCr8
mRatBN7.21213,996,831 - 14,025,457 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1213,997,045 - 14,025,459 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,805,421 - 14,833,628 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,428,689 - 15,456,900 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,455,630 - 14,483,841 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,084,078 - 16,112,672 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,084,266 - 16,112,664 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01218,079,750 - 18,108,497 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41214,463,541 - 14,491,939 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11214,493,375 - 14,518,986 (+)NCBI
Celera1215,756,461 - 15,784,728 (+)NCBICelera
Cytogenetic Map12q11NCBI
Ttyh3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546012,736,086 - 12,766,901 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546012,736,086 - 12,766,907 (+)NCBIChiLan1.0ChiLan1.0
TTYH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v267,588,809 - 7,621,952 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1755,913,524 - 55,946,652 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v072,892,059 - 2,913,447 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.172,985,248 - 3,017,492 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl72,985,248 - 3,017,483 (+)Ensemblpanpan1.1panPan2
TTYH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1614,595,357 - 14,625,417 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl614,595,091 - 14,623,416 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha616,058,186 - 16,088,248 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0614,721,542 - 14,751,629 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl614,721,257 - 14,751,625 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1614,525,527 - 14,555,585 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0614,453,947 - 14,483,999 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0614,739,793 - 14,769,855 (+)NCBIUU_Cfam_GSD_1.0
Ttyh3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344142,724,629 - 142,753,121 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936823298,302 - 326,812 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936823298,317 - 326,806 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTYH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12819,037,300 - 19,072,417 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2819,037,395 - 19,072,458 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660902,698,985 - 2,734,321 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttyh3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474030,360,407 - 30,390,124 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474030,360,496 - 30,389,794 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TTYH3
813 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000008297   ⟹   ENSSSCP00000008078
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl31,826,293 - 1,853,493 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000098427   ⟹   ENSSSCP00000075546
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl31,826,293 - 1,853,493 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000105524   ⟹   ENSSSCP00000076618
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl31,831,000 - 1,853,493 (-)Ensembl
RefSeq Acc Id: XM_021085989   ⟹   XP_020941648
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.131,826,284 - 1,853,520 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085990   ⟹   XP_020941649
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.131,829,305 - 1,853,522 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085991   ⟹   XP_020941650
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.131,826,284 - 1,853,517 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020941648   ⟸   XM_021085989
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TMB9 (UniProtKB/TrEMBL),   A0A8W4F9N6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941650   ⟸   XM_021085991
- Peptide Label: isoform X3
- UniProtKB: F1RI78 (UniProtKB/TrEMBL),   A0A4X1TMB9 (UniProtKB/TrEMBL),   A0A8W4F9N6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941649   ⟸   XM_021085990
- Peptide Label: isoform X2
- UniProtKB: A0A480LQK9 (UniProtKB/TrEMBL),   A0A4X1TI04 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000008078   ⟸   ENSSSCT00000008297
Ensembl Acc Id: ENSSSCP00000075546   ⟸   ENSSSCT00000098427
Ensembl Acc Id: ENSSSCP00000076618   ⟸   ENSSSCT00000105524


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007565 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025065849 UniProtKB/TrEMBL
  ENSSSCG00035047652 UniProtKB/TrEMBL
  ENSSSCG00050023484 UniProtKB/TrEMBL
  ENSSSCG00055005276 UniProtKB/TrEMBL
  ENSSSCG00065026971 UniProtKB/TrEMBL
  ENSSSCG00070010090 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000008297 ENTREZGENE
  ENSSSCT00000008297.5 UniProtKB/TrEMBL
  ENSSSCT00000098427.1 UniProtKB/TrEMBL
  ENSSSCT00000105524 ENTREZGENE
  ENSSSCT00000105524.1 UniProtKB/TrEMBL
  ENSSSCT00025090426.1 UniProtKB/TrEMBL
  ENSSSCT00035063455.1 UniProtKB/TrEMBL
  ENSSSCT00050031698.1 UniProtKB/TrEMBL
  ENSSSCT00055010310.1 UniProtKB/TrEMBL
  ENSSSCT00065036313.1 UniProtKB/TrEMBL
  ENSSSCT00070019636.1 UniProtKB/TrEMBL
  ENSSSCT00070019656.1 UniProtKB/TrEMBL
InterPro Tweety UniProtKB/TrEMBL
NCBI Gene TTYH3 ENTREZGENE
PANTHER PROTEIN TWEETY HOMOLOG 3 UniProtKB/TrEMBL
  PTHR12424 UniProtKB/TrEMBL
Pfam Tweety UniProtKB/TrEMBL
UniProt A0A480LQK9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TI04 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TMB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4F9N6 ENTREZGENE, UniProtKB/TrEMBL
  F1RI78 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:94576 ENTREZGENE