ZNF189 (zinc finger protein 189) - Rat Genome Database

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Gene: ZNF189 (zinc finger protein 189) Sus scrofa
Analyze
Symbol: ZNF189
Name: zinc finger protein 189
RGD ID: 13970436
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); regulation of gene expression (inferred); ASSOCIATED WITH fructose-1,6-bisphosphatase deficiency (ortholog); genetic disease (ortholog); hereditary fructose intolerance syndrome (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1243,106,974 - 243,118,344 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11243,106,911 - 243,117,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21271,660,787 - 271,718,975 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ZNF189
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1243,106,974 - 243,118,344 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11243,106,911 - 243,117,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21271,660,787 - 271,718,975 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF189
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389101,398,851 - 101,410,654 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9101,398,851 - 101,410,660 (+)EnsemblGRCh38hg38GRCh38
GRCh379104,161,133 - 104,172,936 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369103,200,984 - 103,212,763 (+)NCBINCBI36Build 36hg18NCBI36
Build 349101,240,717 - 101,252,497NCBI
Celera974,674,768 - 74,686,547 (+)NCBICelera
Cytogenetic Map9q31.1NCBI
HuRef973,760,586 - 73,772,393 (+)NCBIHuRef
CHM1_19104,307,549 - 104,319,358 (+)NCBICHM1_1
T2T-CHM13v2.09113,570,826 - 113,582,630 (+)NCBIT2T-CHM13v2.0
Zfp189
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39449,521,176 - 49,531,558 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl449,521,176 - 49,531,517 (+)EnsemblGRCm39 Ensembl
GRCm38449,521,176 - 49,531,558 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl449,521,176 - 49,531,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv37449,534,089 - 49,544,417 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36449,542,326 - 49,552,641 (+)NCBIMGSCv36mm8
Celera449,549,471 - 49,559,799 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.55NCBI
Zfp189
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8568,668,225 - 68,679,606 (+)NCBIGRCr8
mRatBN7.2563,872,596 - 63,884,348 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl563,872,738 - 63,884,121 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx565,803,448 - 65,815,282 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0567,622,780 - 67,634,614 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0567,592,160 - 67,603,994 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0564,789,432 - 64,801,079 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl564,789,456 - 64,800,810 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0569,280,812 - 69,292,492 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4566,266,848 - 66,278,203 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1566,272,310 - 66,283,349 (+)NCBI
Celera563,723,898 - 63,735,254 (-)NCBICelera
Cytogenetic Map5q22NCBI
Znf189
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541924,404,827 - 24,416,093 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541924,403,858 - 24,416,395 (-)NCBIChiLan1.0ChiLan1.0
ZNF189
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21137,951,986 - 37,963,935 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1937,954,358 - 37,966,308 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0972,607,439 - 72,619,319 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19100,601,555 - 100,613,409 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9100,601,561 - 100,613,409 (+)Ensemblpanpan1.1panPan2
ZNF189
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11158,129,654 - 58,141,727 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1158,129,001 - 58,140,713 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1156,574,085 - 56,587,449 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01159,265,136 - 59,278,502 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1159,266,174 - 59,278,499 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11157,774,881 - 57,788,233 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01157,787,957 - 57,801,309 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01158,485,508 - 58,498,883 (+)NCBIUU_Cfam_GSD_1.0
Znf189
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947173,017,018 - 173,028,296 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365249,564,941 - 9,574,761 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365249,564,599 - 9,575,783 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF189
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11238,030,256 - 38,042,169 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660354,511,774 - 4,523,639 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf189
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247589,888,113 - 9,900,933 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZNF189
265 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 2 13 1
Low 10 4 3 2 10 1 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000039074   ⟹   ENSSSCP00000049942
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1243,106,974 - 243,116,882 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000049810   ⟹   ENSSSCP00000055235
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1243,107,074 - 243,118,344 (+)Ensembl
RefSeq Acc Id: XM_005652705   ⟹   XP_005652762
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11243,106,911 - 243,117,929 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005652762 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000049942.2
  ENSSSCP00000055235
  ENSSSCP00000055235.1
Reference Protein Sequences
RefSeq Acc Id: XP_005652762   ⟸   XM_005652705
- Sequence:
RefSeq Acc Id: ENSSSCP00000049942   ⟸   ENSSSCT00000039074
RefSeq Acc Id: ENSSSCP00000055235   ⟸   ENSSSCT00000049810
Protein Domains
C2H2-type   KRAB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034239 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000039074.3 UniProtKB/TrEMBL
  ENSSSCT00000049810 ENTREZGENE
  ENSSSCT00000049810.2 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene ZNF189 ENTREZGENE
PANTHER PR DOMAIN ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 30 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 711 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A287B140_PIG UniProtKB/TrEMBL
  A0A287BGQ5_PIG UniProtKB/TrEMBL
VGNC ID VGNC:103205 ENTREZGENE