DPPA2 (developmental pluripotency associated 2) - Rat Genome Database

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Gene: DPPA2 (developmental pluripotency associated 2) Sus scrofa
Analyze
Symbol: DPPA2
Name: developmental pluripotency associated 2
RGD ID: 13966553
Description: ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN epigenetic regulation of gene expression (ortholog); lung-associated mesenchyme development (ortholog); positive regulation of stem cell proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); primary ovarian insufficiency (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: developmental pluripotency-associated protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13150,186,761 - 150,200,601 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113150,186,833 - 150,200,612 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213159,290,030 - 159,303,777 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DPPA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13150,186,761 - 150,200,601 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113150,186,833 - 150,200,612 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213159,290,030 - 159,303,777 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DPPA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383109,293,788 - 109,316,517 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3109,293,788 - 109,316,517 (-)EnsemblGRCh38hg38GRCh38
GRCh373109,012,635 - 109,035,364 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363110,495,331 - 110,518,054 (-)NCBINCBI36Build 36hg18NCBI36
Build 343110,495,330 - 110,518,054NCBI
Celera3107,411,395 - 107,434,045 (-)NCBICelera
Cytogenetic Map3q13.13NCBI
HuRef3106,386,650 - 106,409,705 (-)NCBIHuRef
CHM1_13108,976,855 - 108,999,582 (-)NCBICHM1_1
T2T-CHM13v2.03112,014,076 - 112,036,840 (-)NCBIT2T-CHM13v2.0
Dppa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391648,130,637 - 48,139,876 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1648,124,271 - 48,140,086 (+)EnsemblGRCm39 Ensembl
GRCm381648,310,274 - 48,319,513 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1648,303,908 - 48,319,723 (+)EnsemblGRCm38mm10GRCm38
MGSCv371648,310,387 - 48,319,626 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361648,229,896 - 48,239,135 (+)NCBIMGSCv36mm8
Celera1648,672,251 - 48,681,510 (+)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1630.75NCBI
Dppa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81166,008,002 - 66,020,044 (-)NCBIGRCr8
mRatBN7.21152,549,024 - 52,556,740 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01155,212,720 - 55,226,328 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Celera1152,150,212 - 52,161,654 (-)NCBICelera
Cytogenetic Map11q21NCBI
DPPA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22107,271,010 - 107,295,962 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13107,275,789 - 107,300,741 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03106,419,537 - 106,442,510 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13113,347,666 - 113,369,485 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3113,347,666 - 113,369,485 (-)Ensemblpanpan1.1panPan2
LOC106559800
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11618,551,215 - 18,552,780 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1619,184,553 - 19,185,458 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01620,280,956 - 20,281,861 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11618,651,307 - 18,652,212 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01619,231,327 - 19,232,232 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01619,284,878 - 19,285,783 (-)NCBIUU_Cfam_GSD_1.0
DPPA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12271,457,486 - 71,481,378 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2271,458,750 - 71,474,328 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604195,007,022 - 95,028,487 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dppa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473139,749,759 - 39,757,389 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DPPA2
372 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 3 1
Below cutoff 4 3 2 3 2 3 2 2 1

Sequence


RefSeq Acc Id: ENSSSCT00000032043   ⟹   ENSSSCP00000020906
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13150,186,761 - 150,200,601 (+)Ensembl
RefSeq Acc Id: XM_003358822   ⟹   XP_003358870
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113150,186,833 - 150,200,612 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003358870 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000020906
  ENSSSCP00000020906.2
  ENSSSCP00005005305.1
  ENSSSCP00025021059.1
  ENSSSCP00050007635.1
  ENSSSCP00055032330.1
  ENSSSCP00070012556.1
RefSeq Acc Id: XP_003358870   ⟸   XM_003358822
- UniProtKB: I3LA40 (UniProtKB/TrEMBL),   A0A4X1T959 (UniProtKB/TrEMBL),   A0A8D0RST8 (UniProtKB/TrEMBL),   A0A8D0HY71 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000020906   ⟸   ENSSSCT00000032043
Protein Domains
SAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031524 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005005900 UniProtKB/TrEMBL
  ENSSSCG00025036174 UniProtKB/TrEMBL
  ENSSSCG00050013740 UniProtKB/TrEMBL
  ENSSSCG00055020699 UniProtKB/TrEMBL
  ENSSSCG00070007876 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000032043 ENTREZGENE
  ENSSSCT00000032043.4 UniProtKB/TrEMBL
  ENSSSCT00005008961.1 UniProtKB/TrEMBL
  ENSSSCT00025049266.1 UniProtKB/TrEMBL
  ENSSSCT00050018508.1 UniProtKB/TrEMBL
  ENSSSCT00055040622.1 UniProtKB/TrEMBL
  ENSSSCT00070015187.1 UniProtKB/TrEMBL
InterPro Dppa2/4 UniProtKB/TrEMBL
  Dppa2/4_C_dom UniProtKB/TrEMBL
  Dppa2/4_central_dom UniProtKB/TrEMBL
  SAP_dom UniProtKB/TrEMBL
KEGG Report ssc:100620381 UniProtKB/TrEMBL
NCBI Gene DPPA2 ENTREZGENE
PANTHER PTHR16073 UniProtKB/TrEMBL
  PTHR16073:SF10 UniProtKB/TrEMBL
Pfam DCR UniProtKB/TrEMBL
  Dppa2_A UniProtKB/TrEMBL
PROSITE SAP UniProtKB/TrEMBL
UniProt A0A4X1T959 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0HY71 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0RST8 ENTREZGENE, UniProtKB/TrEMBL
  I3LA40 ENTREZGENE
UniProt Secondary I3LA40 UniProtKB/TrEMBL
VGNC ID VGNC:108653 ENTREZGENE