LMNB1 (lamin B1) - Rat Genome Database
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Gene: LMNB1 (lamin B1) Sus scrofa
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Symbol: LMNB1
Name: lamin B1
RGD ID: 13965778
Description: ENCODES a protein that exhibits double-stranded DNA binding (ortholog); phospholipase binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to corticosterone stimulus (ortholog); cellular response to monosodium L-glutamate (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); COVID-19 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog); lamin filament (ortholog); nuclear envelope (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: lamin-B1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2129,807,318 - 129,871,725 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12129,807,228 - 129,862,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22135,104,017 - 135,158,937 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
LMNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2129,807,318 - 129,871,725 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12129,807,228 - 129,862,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22135,104,017 - 135,158,937 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LMNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5126,776,623 - 126,837,020 (+)EnsemblGRCh38hg38GRCh38
GRCh385126,776,623 - 126,837,020 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375126,112,315 - 126,172,712 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365126,140,732 - 126,200,608 (+)NCBINCBI36hg18NCBI36
Build 345126,140,731 - 126,200,608NCBI
Celera5122,068,688 - 122,128,577 (+)NCBI
Cytogenetic Map5q23.2NCBI
HuRef5121,304,338 - 121,364,498 (+)NCBIHuRef
CHM1_15125,544,889 - 125,605,473 (+)NCBICHM1_1
Lmnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391856,840,885 - 56,886,496 (+)NCBIGRCm39mm39
GRCm381856,707,813 - 56,753,424 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1856,707,813 - 56,753,424 (+)EnsemblGRCm38mm10GRCm38
MGSCv371856,867,467 - 56,913,078 (+)NCBIGRCm37mm9NCBIm37
MGSCv361856,833,242 - 56,878,791 (+)NCBImm8
Celera1858,016,751 - 58,063,869 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1830.84NCBI
Lmnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21850,175,861 - 50,215,210 (+)NCBI
Rnor_6.0 Ensembl1851,785,111 - 51,822,264 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01851,785,111 - 51,822,264 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01850,979,862 - 51,018,232 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,470,605 - 52,508,022 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11852,516,112 - 52,553,517 (+)NCBI
Celera1848,320,757 - 48,358,598 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Lmnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555214,583,671 - 4,612,271 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555214,583,691 - 4,612,271 (+)NCBIChiLan1.0ChiLan1.0
LMNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15127,949,457 - 128,010,721 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5127,949,457 - 128,010,721 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05122,179,513 - 122,240,848 (+)NCBIMhudiblu_PPA_v0panPan3
LMNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1115,930,436 - 16,052,127 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11115,996,627 - 16,052,719 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Lmnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936504157,459 - 211,916 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LMNB1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12329,759,133 - 29,814,332 (+)NCBI
ChlSab1.1 Ensembl2329,759,514 - 29,814,314 (+)Ensembl
Lmnb1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477414,806,585 - 14,863,543 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 2 5 1 3
Low 2 2 3 2 23 2 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000015568   ⟹   ENSSSCP00000015156
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2129,807,321 - 129,862,206 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000046675   ⟹   ENSSSCP00000055044
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2129,807,318 - 129,853,123 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000069617   ⟹   ENSSSCP00000064994
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2129,807,318 - 129,871,725 (+)Ensembl
RefSeq Acc Id: XM_003123882   ⟹   XP_003123930
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12129,807,228 - 129,862,211 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003123930 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003123930   ⟸   XM_003123882
- UniProtKB: F1RKM0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000015156   ⟸   ENSSSCT00000015568
RefSeq Acc Id: ENSSSCP00000064994   ⟸   ENSSSCT00000069617
RefSeq Acc Id: ENSSSCP00000055044   ⟸   ENSSSCT00000046675
Protein Domains
IF rod   LTD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014248 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070016807 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000015156 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000055044 UniProtKB/TrEMBL
  ENSSSCP00000064994 UniProtKB/TrEMBL
  ENSSSCP00070027649 UniProtKB/TrEMBL
  ENSSSCP00070027657 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015568 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000046675 UniProtKB/TrEMBL
  ENSSSCT00000069617 UniProtKB/TrEMBL
  ENSSSCT00070033108 UniProtKB/TrEMBL
  ENSSSCT00070033117 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1160 UniProtKB/TrEMBL
  2.60.40.1260 UniProtKB/TrEMBL
InterPro IF_conserved UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/TrEMBL
  IF_rod_dom_coil1B UniProtKB/TrEMBL
  Lamin_tail_dom UniProtKB/TrEMBL
  Lamin_tail_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:100513342 UniProtKB/TrEMBL
NCBI Gene LMNB1 ENTREZGENE
Pfam Filament UniProtKB/TrEMBL
  LTD UniProtKB/TrEMBL
PROSITE IF_ROD_1 UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/TrEMBL
  LTD UniProtKB/TrEMBL
SMART Filament UniProtKB/TrEMBL
Superfamily-SCOP SSF74853 UniProtKB/TrEMBL
UniProt A0A287BET8_PIG UniProtKB/TrEMBL
  A0A4X1UHX7_PIG UniProtKB/TrEMBL
  A0A5G2R367_PIG UniProtKB/TrEMBL
  F1RKM0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:89760 ENTREZGENE