CKMT2 (creatine kinase, mitochondrial 2) - Rat Genome Database

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Gene: CKMT2 (creatine kinase, mitochondrial 2) Sus scrofa
Analyze
Symbol: CKMT2
Name: creatine kinase, mitochondrial 2
RGD ID: 13962622
Description: ENCODES a protein that exhibits cardiolipin binding (ortholog); INVOLVED IN heart development (ortholog); skeletal muscle tissue development (ortholog); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: creatine kinase S-type, mitochondrial; mitochondrial creatine kinase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl289,796,474 - 89,832,990 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1289,796,470 - 89,830,293 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2291,754,202 - 91,770,538 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CKMT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl289,796,474 - 89,832,990 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1289,796,470 - 89,830,293 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2291,754,202 - 91,770,538 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2p16NCBI
CKMT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38581,233,322 - 81,266,398 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl581,233,320 - 81,266,398 (+)EnsemblGRCh38hg38GRCh38
GRCh37580,529,141 - 80,562,217 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36580,564,895 - 80,597,973 (+)NCBINCBI36Build 36hg18NCBI36
Build 34580,564,937 - 80,597,972NCBI
Celera576,433,409 - 76,466,487 (+)NCBICelera
Cytogenetic Map5q14.1NCBI
HuRef575,738,057 - 75,771,119 (+)NCBIHuRef
CHM1_1579,961,936 - 79,995,008 (+)NCBICHM1_1
T2T-CHM13v2.0581,717,903 - 81,750,979 (+)NCBIT2T-CHM13v2.0
Ckmt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391392,001,510 - 92,025,001 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1392,001,506 - 92,025,004 (-)EnsemblGRCm39 Ensembl
GRCm381391,853,386 - 91,876,923 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1391,853,387 - 91,876,885 (-)EnsemblGRCm38mm10GRCm38
MGSCv371391,992,992 - 92,016,490 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361392,327,626 - 92,351,124 (-)NCBIMGSCv36mm8
Celera1395,480,623 - 95,504,103 (-)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1347.43NCBI
Ckmt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8224,815,008 - 24,845,511 (-)NCBIGRCr8
mRatBN7.2223,079,918 - 23,110,518 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl223,079,918 - 23,110,430 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx230,120,491 - 30,150,955 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0228,220,830 - 28,251,294 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0223,046,970 - 23,076,912 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0221,422,680 - 21,452,797 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl221,422,818 - 21,437,193 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0240,627,924 - 40,657,402 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4222,084,948 - 22,106,014 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1222,005,331 - 22,026,403 (-)NCBI
Celera219,182,609 - 19,209,711 (-)NCBICelera
Cytogenetic Map2q12NCBI
Ckmt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541828,909,915 - 28,927,704 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541828,909,999 - 28,929,109 (-)NCBIChiLan1.0ChiLan1.0
CKMT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2434,028,977 - 34,068,639 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1532,189,632 - 32,222,132 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0534,013,387 - 34,046,522 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1534,324,529 - 34,357,963 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl534,324,529 - 34,356,919 (-)Ensemblpanpan1.1panPan2
CKMT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1326,011,261 - 26,042,646 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl326,011,263 - 26,026,991 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha327,247,362 - 27,263,081 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0325,925,683 - 25,957,453 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl325,925,685 - 25,957,366 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1325,877,524 - 25,893,259 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0325,847,135 - 25,862,863 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0326,126,835 - 26,142,587 (-)NCBIUU_Cfam_GSD_1.0
Ckmt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213182,027,158 - 182,049,174 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936469575,785 - 598,612 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936469575,836 - 598,601 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CKMT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1475,379,181 - 75,414,640 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl475,398,939 - 75,414,715 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604924,253,413 - 24,288,192 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ckmt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247431,791,423 - 1,812,970 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247431,791,040 - 1,812,970 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CKMT2
1305 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 2
Low 2 3 11 2
Below cutoff 7 2 4 12 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000015432   ⟹   ENSSSCP00000015023
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl289,816,789 - 89,830,286 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000040032   ⟹   ENSSSCP00000044339
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl289,797,117 - 89,832,990 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000040518   ⟹   ENSSSCP00000054011
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl289,808,433 - 89,832,819 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000052447   ⟹   ENSSSCP00000033868
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl289,808,433 - 89,832,819 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000084518   ⟹   ENSSSCP00000063621
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl289,796,474 - 89,830,285 (+)Ensembl
RefSeq Acc Id: NM_001044551   ⟹   NP_001038016
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1289,814,141 - 89,830,288 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021082288   ⟹   XP_020937947
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1289,796,470 - 89,830,293 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020937947   ⟸   XM_021082288
- Peptide Label: isoform X1
- UniProtKB: A0A8D1J9T6 (UniProtKB/TrEMBL),   Q2HYU1 (UniProtKB/TrEMBL),   A0A4X1T6K3 (UniProtKB/TrEMBL),   A0A8D0T8C8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001038016   ⟸   NM_001044551
- UniProtKB: Q2HYU1 (UniProtKB/TrEMBL),   A0A8D1J9T6 (UniProtKB/TrEMBL),   A0A4X1T6K3 (UniProtKB/TrEMBL),   A0A8D0T8C8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000044339   ⟸   ENSSSCT00000040032
RefSeq Acc Id: ENSSSCP00000015023   ⟸   ENSSSCT00000015432
RefSeq Acc Id: ENSSSCP00000054011   ⟸   ENSSSCT00000040518
RefSeq Acc Id: ENSSSCP00000063621   ⟸   ENSSSCT00000084518
RefSeq Acc Id: ENSSSCP00000033868   ⟸   ENSSSCT00000052447
Protein Domains
Phosphagen kinase C-terminal   Phosphagen kinase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014128 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005013212 UniProtKB/TrEMBL
  ENSSSCG00015050138 UniProtKB/TrEMBL
  ENSSSCG00025069940 UniProtKB/TrEMBL
  ENSSSCG00030042541 UniProtKB/TrEMBL
  ENSSSCG00035046573 UniProtKB/TrEMBL
  ENSSSCG00040002048 UniProtKB/TrEMBL
  ENSSSCG00045036690 UniProtKB/TrEMBL
  ENSSSCG00050067296 UniProtKB/TrEMBL
  ENSSSCG00055008244 UniProtKB/TrEMBL
  ENSSSCG00065019956 UniProtKB/TrEMBL
  ENSSSCG00070006762 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015432 ENTREZGENE
  ENSSSCT00000015432.4 UniProtKB/TrEMBL
  ENSSSCT00000040032.3 UniProtKB/TrEMBL
  ENSSSCT00000040518.3 UniProtKB/TrEMBL
  ENSSSCT00000052447.3 UniProtKB/TrEMBL
  ENSSSCT00000084518 ENTREZGENE
  ENSSSCT00000084518.1 UniProtKB/TrEMBL
  ENSSSCT00005021831.1 UniProtKB/TrEMBL
  ENSSSCT00005022061.1 UniProtKB/TrEMBL
  ENSSSCT00005022208.1 UniProtKB/TrEMBL
  ENSSSCT00005022227.1 UniProtKB/TrEMBL
  ENSSSCT00005022244.1 UniProtKB/TrEMBL
  ENSSSCT00005022360.1 UniProtKB/TrEMBL
  ENSSSCT00005022385.1 UniProtKB/TrEMBL
  ENSSSCT00015066848.1 UniProtKB/TrEMBL
  ENSSSCT00025097019.1 UniProtKB/TrEMBL
  ENSSSCT00025097178.1 UniProtKB/TrEMBL
  ENSSSCT00025097315.1 UniProtKB/TrEMBL
  ENSSSCT00030059249.1 UniProtKB/TrEMBL
  ENSSSCT00035061936.1 UniProtKB/TrEMBL
  ENSSSCT00040002470.1 UniProtKB/TrEMBL
  ENSSSCT00045063181.1 UniProtKB/TrEMBL
  ENSSSCT00050091791.1 UniProtKB/TrEMBL
  ENSSSCT00055016096.1 UniProtKB/TrEMBL
  ENSSSCT00065026591.1 UniProtKB/TrEMBL
  ENSSSCT00070013059.1 UniProtKB/TrEMBL
  ENSSSCT00070013066.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.135.10 UniProtKB/TrEMBL
  Glutamine synthetase/guanido kinase, catalytic domain UniProtKB/TrEMBL
InterPro ATP-guanido_PTrfase UniProtKB/TrEMBL
  ATP-guanido_PTrfase_AS UniProtKB/TrEMBL
  ATP-guanido_PTrfase_cat UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N_sf UniProtKB/TrEMBL
  Gln_synth/guanido_kin_cat_dom UniProtKB/TrEMBL
KEGG Report ssc:733602 UniProtKB/TrEMBL
NCBI Gene CKMT2 ENTREZGENE
PANTHER CREATINE KINASE S-TYPE, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR11547 UniProtKB/TrEMBL
Pfam ATP-gua_Ptrans UniProtKB/TrEMBL
  ATP-gua_PtransN UniProtKB/TrEMBL
PROSITE PHOSPHAGEN_KINASE UniProtKB/TrEMBL
  PHOSPHAGEN_KINASE_C UniProtKB/TrEMBL
  PHOSPHAGEN_KINASE_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48034 UniProtKB/TrEMBL
  SSF55931 UniProtKB/TrEMBL
UniProt A0A286ZQI3_PIG UniProtKB/TrEMBL
  A0A287BBV9_PIG UniProtKB/TrEMBL
  A0A4X1T6K3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1T7M8_PIG UniProtKB/TrEMBL
  A0A8D0IHC6_PIG UniProtKB/TrEMBL
  A0A8D0LJJ7_PIG UniProtKB/TrEMBL
  A0A8D0T8C8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1A4I3_PIG UniProtKB/TrEMBL
  A0A8D1A5K1_PIG UniProtKB/TrEMBL
  A0A8D1J9T6 ENTREZGENE
  F6PU58_PIG UniProtKB/TrEMBL
  Q2HYU1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287AKB5 UniProtKB/TrEMBL
  A0A8D1J9T6 UniProtKB/TrEMBL
VGNC ID VGNC:86719 ENTREZGENE