PLP1 (proteolipid protein 1) - Rat Genome Database
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Gene: PLP1 (proteolipid protein 1) Sus scrofa
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Symbol: PLP1
Name: proteolipid protein 1
RGD ID: 13962157
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein-containing complex binding (ortholog); structural constituent of myelin sheath (ortholog); INVOLVED IN AMPA selective glutamate receptor signaling pathway (ortholog); astrocyte development (ortholog); axon development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Chronic Relapsing Experimental Autoimmune Encephalomyelitis (ortholog); demyelinating disease (ortholog); FOUND IN integrin alphav-beta3 complex (ortholog); myelin sheath (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: lipophilin; myelin proteolipid protein; PLP; proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated); proteolipid protein, lipophilin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX84,665,925 - 84,695,533 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X84,676,627 - 84,683,517 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X98,648,731 - 98,655,621 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:10441741  


Genomics

Comparative Map Data
PLP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX84,665,925 - 84,695,533 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X84,676,627 - 84,683,517 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X98,648,731 - 98,655,621 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX103,773,718 - 103,792,619 (+)EnsemblGRCh38hg38GRCh38
GRCh38X103,776,506 - 103,792,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X103,031,434 - 103,047,548 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37X103,031,439 - 103,047,548 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X102,918,410 - 102,934,204 (+)NCBINCBI36hg18NCBI36
Build 34X102,837,898 - 102,853,690NCBI
CeleraX103,470,449 - 103,486,558 (+)NCBI
Cytogenetic MapXq22.2NCBI
HuRefX92,687,547 - 92,703,609 (+)NCBIHuRef
CHM1_1X102,924,421 - 102,940,535 (+)NCBICHM1_1
Plp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X135,720,897 - 135,739,331 (+)NCBIGRCm39mm39
GRCm38X136,820,148 - 136,838,582 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX136,822,671 - 136,839,733 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X133,357,375 - 133,372,282 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X132,169,200 - 132,184,107 (+)NCBImm8
CeleraX120,104,727 - 120,119,592 (+)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX59.1NCBI
Plp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X100,184,039 - 100,201,035 (+)NCBI
Rnor_6.0 EnsemblX107,496,072 - 107,511,348 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X107,494,326 - 107,511,355 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X107,379,831 - 107,394,881 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X124,488,627 - 124,503,639 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X124,562,059 - 124,577,072 (+)NCBI
CeleraX101,020,110 - 101,035,276 (+)NCBICelera
Cytogenetic MapXq32NCBI
Plp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955548781,015 - 797,935 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955548781,522 - 797,246 (+)NCBIChiLan1.0ChiLan1.0
PLP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X103,353,181 - 103,412,513 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX103,353,184 - 103,412,513 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X93,015,098 - 93,031,193 (+)NCBIMhudiblu_PPA_v0panPan3
PLP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX77,191,150 - 77,205,964 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X77,191,112 - 77,207,772 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Plp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649910,534,953 - 10,553,411 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X91,671,535 - 91,687,693 (+)NCBI
ChlSab1.1 EnsemblX91,671,878 - 91,687,878 (+)Ensembl
Plp1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624954135,065 - 150,911 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system musculoskeletal system nervous system reproductive system
High 15
Medium 5
Low 5 1 1 2
Below cutoff 5 1 2 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000013705   ⟹   ENSSSCP00000013328
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX84,667,110 - 84,685,059 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000033433   ⟹   ENSSSCP00000030526
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX84,665,925 - 84,695,533 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000035182   ⟹   ENSSSCP00000029109
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX84,667,106 - 84,685,062 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000036108   ⟹   ENSSSCP00000058966
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX84,667,106 - 84,685,060 (+)Ensembl
RefSeq Acc Id: NM_213974   ⟹   NP_999139
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X84,676,627 - 84,683,517 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_999139 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA51735 (Get FASTA)   NCBI Sequence Viewer  
  CAB51809 (Get FASTA)   NCBI Sequence Viewer  
  Q712P7 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_999139   ⟸   NM_213974
- UniProtKB: Q712P7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000058966   ⟸   ENSSSCT00000036108
RefSeq Acc Id: ENSSSCP00000029109   ⟸   ENSSSCT00000035182
RefSeq Acc Id: ENSSSCP00000013328   ⟸   ENSSSCT00000013705
RefSeq Acc Id: ENSSSCP00000030526   ⟸   ENSSSCT00000033433


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012536 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00040062688 UniProtKB/Swiss-Prot
  ENSSSCG00045039419 UniProtKB/Swiss-Prot
  ENSSSCG00055015576 UniProtKB/Swiss-Prot
  ENSSSCG00070028858 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000013328 UniProtKB/TrEMBL
  ENSSSCP00000029109 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000030526 UniProtKB/TrEMBL
  ENSSSCP00000058966 UniProtKB/TrEMBL
  ENSSSCP00040037867 UniProtKB/Swiss-Prot
  ENSSSCP00045048872 UniProtKB/Swiss-Prot
  ENSSSCP00055024442 UniProtKB/Swiss-Prot
  ENSSSCP00070049216 UniProtKB/TrEMBL
  ENSSSCP00070049218 UniProtKB/TrEMBL
  ENSSSCP00070049219 UniProtKB/TrEMBL
  ENSSSCP00070049221 UniProtKB/TrEMBL
  ENSSSCP00070049224 UniProtKB/Swiss-Prot
  ENSSSCP00070049226 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000013705 UniProtKB/TrEMBL
  ENSSSCT00000033433 UniProtKB/TrEMBL
  ENSSSCT00000035182 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000036108 UniProtKB/TrEMBL
  ENSSSCT00040086369 UniProtKB/Swiss-Prot
  ENSSSCT00045068654 UniProtKB/Swiss-Prot
  ENSSSCT00055030702 UniProtKB/Swiss-Prot
  ENSSSCT00070057893 UniProtKB/TrEMBL
  ENSSSCT00070057895 UniProtKB/TrEMBL
  ENSSSCT00070057896 UniProtKB/TrEMBL
  ENSSSCT00070057898 UniProtKB/TrEMBL
  ENSSSCT00070057901 UniProtKB/Swiss-Prot
  ENSSSCT00070057904 UniProtKB/TrEMBL
InterPro Myelin_PLP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myelin_PLP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397029 UniProtKB/Swiss-Prot
NCBI Gene PLP1 ENTREZGENE
PANTHER PTHR11683 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Myelin_PLP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS MYELINPLP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MYELIN_PLP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYELIN_PLP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PLP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287BR21_PIG UniProtKB/TrEMBL
  A0A4X1VZD1_PIG UniProtKB/TrEMBL
  A0A4X1W424_PIG UniProtKB/TrEMBL
  A0A4X1W506_PIG UniProtKB/TrEMBL
  A0A4X1W512_PIG UniProtKB/TrEMBL
  A0A4X1W584_PIG UniProtKB/TrEMBL
  A0A5S6GB55_PIG UniProtKB/TrEMBL
  K7GML6_PIG UniProtKB/TrEMBL
  K7GRJ9_PIG UniProtKB/TrEMBL
  MYPR_PIG UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:91569 ENTREZGENE