TLN2 (talin 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: TLN2 (talin 2) Sus scrofa
Analyze
Symbol: TLN2
Name: talin 2
RGD ID: 13960385
Description: ENCODES a protein that exhibits actin filament binding (inferred); structural constituent of cytoskeleton (inferred); INVOLVED IN cell adhesion (inferred); cytoskeleton organization (inferred); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colon cancer (ortholog); FOUND IN fascia adherens (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: talin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1109,208,672 - 109,680,199 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11109,208,663 - 109,680,663 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21120,431,291 - 120,698,794 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
TLN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1109,208,672 - 109,680,199 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11109,208,663 - 109,680,663 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21120,431,291 - 120,698,794 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TLN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1562,390,526 - 62,844,631 (+)EnsemblGRCh38hg38GRCh38
GRCh381562,390,523 - 62,844,631 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371562,939,510 - 63,136,830 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361560,726,802 - 60,923,883 (+)NCBINCBI36hg18NCBI36
Build 341560,726,801 - 60,920,733NCBI
Celera1539,819,286 - 40,016,441 (+)NCBI
Cytogenetic Map15q22.2NCBI
HuRef1539,762,354 - 39,959,569 (+)NCBIHuRef
CHM1_11563,058,568 - 63,256,014 (+)NCBICHM1_1
Tln2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39967,124,367 - 67,541,357 (-)NCBIGRCm39mm39
GRCm39 Ensembl967,124,369 - 67,466,985 (-)Ensembl
GRCm38967,217,085 - 67,634,045 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl967,217,087 - 67,559,703 (-)EnsemblGRCm38mm10GRCm38
MGSCv37967,064,892 - 67,407,510 (-)NCBIGRCm37mm9NCBIm37
MGSCv36967,017,280 - 67,338,759 (-)NCBImm8
MGSCv36967,820,018 - 68,028,925 (-)NCBImm8
Celera964,440,386 - 64,782,550 (-)NCBICelera
Cytogenetic Map9CNCBI
Tln2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2867,830,920 - 68,252,223 (-)NCBI
Rnor_6.0 Ensembl873,014,137 - 73,194,837 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0873,009,980 - 73,441,536 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0877,342,736 - 77,771,053 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4871,532,270 - 71,964,142 (-)NCBIRGSC3.4rn4RGSC3.4
Celera873,455,547 - 73,874,934 (+)NCBICelera
Cytogenetic Map8q24NCBI
Tln2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545012,394,377 - 12,728,925 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545012,391,049 - 12,740,232 (-)NCBIChiLan1.0ChiLan1.0
TLN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11559,635,488 - 60,088,662 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1559,892,920 - 60,088,414 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01541,337,084 - 41,790,949 (+)NCBIMhudiblu_PPA_v0panPan3
TLN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13027,023,731 - 27,452,575 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3027,257,948 - 27,449,267 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3026,939,212 - 27,366,590 (+)NCBI
ROS_Cfam_1.03027,192,437 - 27,619,533 (+)NCBI
UMICH_Zoey_3.13027,129,804 - 27,556,957 (+)NCBI
UNSW_CanFamBas_1.03027,191,240 - 27,619,171 (+)NCBI
UU_Cfam_GSD_1.03027,434,199 - 27,862,607 (+)NCBI
Tln2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640105,225,660 - 105,631,223 (+)NCBI
SpeTri2.0NW_00493647123,073,267 - 23,479,286 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TLN2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12620,688,048 - 21,140,585 (-)NCBI
ChlSab1.1 Ensembl2620,691,779 - 20,940,450 (-)Ensembl
Tln2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247819,626,031 - 10,030,427 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 1 2 18 1
Low 10 2 2 5 5 1 3 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021094255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021094340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK393676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU210863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01093315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000025342   ⟹   ENSSSCP00000022185
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1109,208,672 - 109,584,727 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000051920   ⟹   ENSSSCP00000050506
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1109,208,838 - 109,680,199 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000074428   ⟹   ENSSSCP00000072069
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1109,208,838 - 109,680,199 (-)Ensembl
RefSeq Acc Id: XM_021094255   ⟹   XP_020949914
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,664 - 109,680,206 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094262   ⟹   XP_020949921
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,663 - 109,605,795 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094269   ⟹   XP_020949928
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,663 - 109,639,737 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094275   ⟹   XP_020949934
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,663 - 109,678,995 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094283   ⟹   XP_020949942
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,663 - 109,680,663 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094290   ⟹   XP_020949949
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,664 - 109,680,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094295   ⟹   XP_020949954
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,663 - 109,475,967 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094297   ⟹   XP_020949956
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,663 - 109,501,631 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094302   ⟹   XP_020949961
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,663 - 109,546,074 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094311   ⟹   XP_020949970
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,664 - 109,680,206 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094320   ⟹   XP_020949979
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,664 - 109,680,206 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094327   ⟹   XP_020949986
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,664 - 109,680,206 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094334   ⟹   XP_020949993
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,664 - 109,680,199 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094340   ⟹   XP_020949999
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11109,208,664 - 109,680,206 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020949942   ⟸   XM_021094283
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949934   ⟸   XM_021094275
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949928   ⟸   XM_021094269
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949921   ⟸   XM_021094262
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949961   ⟸   XM_021094302
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949956   ⟸   XM_021094297
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949954   ⟸   XM_021094295
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949999   ⟸   XM_021094340
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_020949979   ⟸   XM_021094320
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020949986   ⟸   XM_021094327
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_020949970   ⟸   XM_021094311
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020949914   ⟸   XM_021094255
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949993   ⟸   XM_021094334
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_020949949   ⟸   XM_021094290
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000022185   ⟸   ENSSSCT00000025342
RefSeq Acc Id: ENSSSCP00000072069   ⟸   ENSSSCT00000074428
RefSeq Acc Id: ENSSSCP00000050506   ⟸   ENSSSCT00000051920
Protein Domains
FERM   I/LWEQ   VBS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024088 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070012058 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000022185 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000050506 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000072069 UniProtKB/TrEMBL
  ENSSSCP00070020027 UniProtKB/TrEMBL
  ENSSSCP00070020052 UniProtKB/TrEMBL
  ENSSSCP00070020098 UniProtKB/TrEMBL
  ENSSSCP00070020137 UniProtKB/TrEMBL
  ENSSSCP00070020149 UniProtKB/TrEMBL
  ENSSSCP00070020160 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000025342 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000051920 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000074428 UniProtKB/TrEMBL
  ENSSSCT00070024203 UniProtKB/TrEMBL
  ENSSSCT00070024234 UniProtKB/TrEMBL
  ENSSSCT00070024286 UniProtKB/TrEMBL
  ENSSSCT00070024332 UniProtKB/TrEMBL
  ENSSSCT00070024348 UniProtKB/TrEMBL
  ENSSSCT00070024361 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Alpha-catenin/vinculin-like_sf UniProtKB/TrEMBL
  Band_41_domain UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_CS UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FERM_f0 UniProtKB/TrEMBL
  I/LWEQ_dom_sf UniProtKB/TrEMBL
  ILWEQ_dom UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  Talin1/2-RS UniProtKB/TrEMBL
  Talin_cent UniProtKB/TrEMBL
  Talin_cent_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  Vinculin-bd_dom UniProtKB/TrEMBL
NCBI Gene TLN2 ENTREZGENE
Pfam FERM_f0 UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  I_LWEQ UniProtKB/TrEMBL
  Talin_middle UniProtKB/TrEMBL
  VBS UniProtKB/TrEMBL
PROSITE FERM_2 UniProtKB/TrEMBL
  FERM_3 UniProtKB/TrEMBL
  I_LWEQ UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  ILWEQ UniProtKB/TrEMBL
Superfamily-SCOP SSF109880 UniProtKB/TrEMBL
  SSF109885 UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
  SSF47220 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A287B272_PIG UniProtKB/TrEMBL
  A0A4X1TSC3_PIG UniProtKB/TrEMBL
  A0A4X1TUP0_PIG UniProtKB/TrEMBL
  A0A4X1TX13_PIG UniProtKB/TrEMBL
  A0A4X1TXB8_PIG UniProtKB/TrEMBL
  A0A4X1TXC8_PIG UniProtKB/TrEMBL
  A0A5G2RJK9_PIG UniProtKB/TrEMBL
  I3LDQ1_PIG UniProtKB/TrEMBL
VGNC ID VGNC:103190 ENTREZGENE