LOC100522675 (taste receptor type 2 member 10)

Gene: LOC100522675 (taste receptor type 2 member 10) Sus scrofa

Analyze

Symbol:

LOC100522675 (Ensembl: TAS2R10)

Name:

taste receptor type 2 member 10 (Ensembl:taste 2 receptor member 10)

RGD ID:

13959027

Description:

ENCODES a protein that exhibits bitter taste receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of bitter taste (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of taste (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

TAS2R10; taste 2 receptor member 10

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	61,242,636 - 61,243,565 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	61,242,320 - 61,244,023 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	63,965,446 - 63,966,375 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of bitter taste (IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of taste (IEA)

Cellular Component

membrane (IBA,IEA)

Molecular Function

bitter taste receptor activity (IEA)

G protein-coupled receptor activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC100522675
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	61,242,636 - 61,243,565 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	61,242,320 - 61,244,023 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	63,965,446 - 63,966,375 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TAS2R10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	10,825,219 - 10,826,358 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	10,825,219 - 10,826,358 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	10,977,818 - 10,978,957 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	10,869,212 - 10,870,135 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	10,869,211 - 10,870,135	NCBI
Celera	12	16,126,257 - 16,127,180 (-)	NCBI		Celera
Cytogenetic Map	12	p13.2	NCBI
HuRef	12	10,706,782 - 10,707,705 (-)	NCBI		HuRef
CHM1_1	12	10,947,306 - 10,948,229 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	10,698,316 - 10,699,455 (-)	NCBI		T2T-CHM13v2.0

Tas2r114
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	131,666,097 - 131,667,026 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	131,666,097 - 131,667,026 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	131,689,134 - 131,690,063 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	131,689,134 - 131,690,063 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	131,639,152 - 131,640,081 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	131,654,827 - 131,655,756 (-)	NCBI		MGSCv36	mm8
Celera	6	134,128,153 - 134,129,082 (+)	NCBI		Celera
Cytogenetic Map	6	F3	NCBI
cM Map	6	63.54	NCBI

Tas2r107
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	167,031,081 - 167,032,007 (-)	NCBI		GRCr8
mRatBN7.2	4	165,299,663 - 165,300,589 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	165,299,663 - 165,300,589 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	171,584,465 - 171,585,391 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	167,367,486 - 167,368,412 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	166,001,532 - 166,002,458 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	165,773,200 - 165,774,126 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	165,773,200 - 165,774,126 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	228,336,760 - 228,337,686 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	169,254,152 - 169,255,078 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	169,499,087 - 169,500,014 (-)	NCBI
Celera	4	153,900,446 - 153,901,372 (-)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

TAS2R10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	16,296,571 - 16,300,565 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	16,293,327 - 16,295,935 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	10,853,735 - 10,856,329 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	11,119,809 - 11,120,878 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	11,119,955 - 11,120,878 (-)	Ensembl	panpan1.1		panPan2

TAS2R10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	34,876,090 - 34,877,058 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	34,876,090 - 34,877,058 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	11,571,386 - 11,572,354 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	35,184,276 - 35,185,244 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	35,184,276 - 35,185,244 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	35,074,217 - 35,075,188 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	35,023,872 - 35,024,843 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	11,299,629 - 11,300,600 (-)	NCBI		UU_Cfam_GSD_1.0

TAS2R10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	10,636,263 - 10,641,326 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	10,639,630 - 10,640,550 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666089	2,715,849 - 2,718,264 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tas2r10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624752	27,478,945 - 27,479,874 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in LOC100522675
35 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system
High
Medium
Low
Below cutoff	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003126498	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU856689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000045369 ⟹ ENSSSCP00000049240

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	61,242,636 - 61,243,565 (+)	Ensembl

RefSeq Acc Id:

XM_003126498 ⟹ XP_003126546

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	61,242,320 - 61,244,023 (+)	NCBI

Sequence:

show sequence

AACAAATGCAAAATGGTGTCAGGAGGACAGATAAAATCCATGAAACAGAAACTTTCATTTGCAT
GTTAACAAATTATAGGTAGGCATTCTGTATGAAACTACATTATGAGTACCAGCTAAACTGTATA
GGCATAACTGGAGGGGGTCTCTATGAAGATATTTTGGATTCCATCACAAGGCATTAATTGGGAT
ACTTTTAAGTCTTTCTGTAATCGAAGAGAAGAAATCATTCTTCCATCAAGCAACAACGTATGCC
TCATTCTGCAGCCGGTAATCTAAATAGATGTAAAGAAAACAATATCAGGGATTGGCAGATATGC
TAAGTATAGTAGAAAGCCTCCTCATTTTTATATCAGTTAGTCAGTCAATATTGGGGTTTTTAGG
GAATGGATTTATTGGACTTGTAACCTGCATTGACTGTGTGAAAAACAAGAACATCTCTATGATC
AGCTTTATTCTCACTGGCTTAGCTACTTCAAGAATTTGTCTGATATGGTTAATAATTATAGATG
GATTTATAAAGATATTCTTTCCAGATTTATATATTTCTGGTAAACTAACTGAATACATTAGTTA
CTCATGGGTAATTGTCAATCATTCAAGTATCTGGTTTGCCACCAGCCTCAGCATCTTCTATTTC
CTGAAGATAGCAAATTTTTCCCACCACATTTTTCTTTGGTTGAAGGGTAAAATCAATAGGGTTC
TTCTCATTCTGATGGGATACTTGTTTATTTCATGGTTATTTACTTTTCCACAAGTTGTGAAGAT
TATTAGTGACAGTAAAAAGAAGAATGGAAGTTCATTCTGGCCACTCAACATGCATAAACTTGAA
TACTTTATGAGCCAGTTTTTGCTCAATCTGGGTGTCATTCTCCTCTTTATACTATGCATGATTA
CATGTTTCTTATTGATCATTTCTCTTTGGAGGCACAACAGGCAGATGCAATCGAATGCCACTGG
ATTCAGAGACCCCAGCACAGAAGCACATATTAAAGCAATGAAAATTGTGATATCTTTTATCATC
CTCTTTATCTTGTATTTTATAGGCGTTGCCATAGAAATATCATGTGGTACTCAGCCAGAAAACA
AACTGCTGTTTATTTTTGGTATGATAACCACAGCCATTTTTCCTTGGGGTCACTCATTTATCCT
AATTCTAGGAAACAAGAAGCTAAAGCAAGCCTCTTTGAAGGTACTGAAGCAATTAAAGTGCTGG
GGAAAAGAGAAACTTCTCAGAACTCCATGATTACCTTGGTGAGAAATGGGTGGTCCAAGAAAAC
AATTCAGTAAAGAAATCCCTGAAGACCTCTTTCACTTGCATTCTTTCTCGCATTGGTTTTAACT
GTTATTGAACATCACTAAAATCTTCCATAATGACTGACTACATTTCAGAGGATCTCACTCTTCA
ATGAGACTTTAATCCCACATACAAATTGAGTGGCTCAGTCAGCTTTCCTCCCTTGAAATTGCTT
CTTCCCACATCCCCCATCGCCAGAGGAAAAAACAGCTTGGAGACTATTCAATATAAAGATGCTA
ATGGTGGGAATAAGTCTCTAAAACAAAATTTCTCATTGTGCTTTATATGACTTCCCTAAAGCAT
TGACAGCCCTTCACCAGGAAAACCCAAAGAAAAAGAAACCAAGACAAAGAAAAATTATAATCAG
TCTTGCCACTTAGAACATGGAAGTGAGAAAGACAGGTGCT

hide sequence

Protein Sequences


Protein RefSeqs	XP_003126546	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000049240
	ENSSSCP00000049240.1
	ENSSSCP00015038260.1
	ENSSSCP00025000964.1
	ENSSSCP00030043335.1
	ENSSSCP00045038765.1
	ENSSSCP00055022213.1
	ENSSSCP00060005060.1
	ENSSSCP00065042938.1

RefSeq Acc Id:

XP_003126546 ⟸ XM_003126498

- UniProtKB:

A0A287AYK0 (UniProtKB/TrEMBL), A0A8D1IVZ4 (UniProtKB/TrEMBL), A0A8D0UB59 (UniProtKB/TrEMBL), A0A8D0XYQ2 (UniProtKB/TrEMBL), A0A8D1ZVP7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSIVESLLIFISVSQSILGFLGNGFIGLVTCIDCVKNKNISMISFILTGLATSRICLIWLIII
DGFIKIFFPDLYISGKLTEYISYSWVIVNHSSIWFATSLSIFYFLKIANFSHHIFLWLKGKINR
VLLILMGYLFISWLFTFPQVVKIISDSKKKNGSSFWPLNMHKLEYFMSQFLLNLGVILLFILCM
ITCFLLIISLWRHNRQMQSNATGFRDPSTEAHIKAMKIVISFIILFILYFIGVAIEISCGTQPE
NKLLFIFGMITTAIFPWGHSFILILGNKKLKQASLKVLKQLKCWGKEKLLRTP

hide sequence

RefSeq Acc Id:

ENSSSCP00000049240 ⟸ ENSSSCT00000045369

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000038925	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015069756	UniProtKB/TrEMBL
	ENSSSCG00025002154	UniProtKB/TrEMBL
	ENSSSCG00030067256	UniProtKB/TrEMBL
	ENSSSCG00045032571	UniProtKB/TrEMBL
	ENSSSCG00055014151	UniProtKB/TrEMBL
	ENSSSCG00060010262	UniProtKB/TrEMBL
	ENSSSCG00065071298	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000045369	ENTREZGENE
	ENSSSCT00000045369.1	UniProtKB/TrEMBL
	ENSSSCT00015093424.1	UniProtKB/TrEMBL
	ENSSSCT00025002746.1	UniProtKB/TrEMBL
	ENSSSCT00030094024.1	UniProtKB/TrEMBL
	ENSSSCT00045055579.1	UniProtKB/TrEMBL
	ENSSSCT00055027891.1	UniProtKB/TrEMBL
	ENSSSCT00060013295.1	UniProtKB/TrEMBL
	ENSSSCT00065097954.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	T2R	UniProtKB/TrEMBL
KEGG Report	ssc:100522675	UniProtKB/TrEMBL
NCBI Gene	LOC100522675	ENTREZGENE
PANTHER	TASTE RECEPTOR TYPE 2	UniProtKB/TrEMBL
	TASTE RECEPTOR TYPE 2 MEMBER 10	UniProtKB/TrEMBL
Pfam	TAS2R	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A287AYK0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0UB59	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0XYQ2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1IVZ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1ZVP7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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