GNRHR2 (gonadotropin releasing hormone receptor 2) - Rat Genome Database

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Gene: GNRHR2 (gonadotropin releasing hormone receptor 2) Sus scrofa
Analyze
Symbol: GNRHR2
Name: gonadotropin releasing hormone receptor 2
RGD ID: 13956140
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); peptide binding (inferred); protein-hormone receptor activity (inferred); INVOLVED IN cellular response to gonadotropin-releasing hormone (inferred); cellular response to hormone stimulus (inferred); G protein-coupled receptor signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GnRH II receptor 7 transmembrane; gonadotropin-releasing hormone (type 2) receptor 2; gonadotropin-releasing hormone receptor 2
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1499,409,569 - 99,415,346 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24109,053,018 - 109,057,358 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:27134031   PMID:28534229   PMID:30032202   PMID:30930217  


Genomics

Comparative Map Data
GNRHR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1499,409,569 - 99,415,346 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24109,053,018 - 109,057,358 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GNRHR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381145,919,013 - 145,925,341 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1145,919,013 - 145,925,341 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl1145,919,344 - 145,925,233 (+)EnsemblGRCh38hg38GRCh38
GRCh371145,509,752 - 145,516,076 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361144,221,177 - 144,227,433 (-)NCBINCBI36Build 36hg18NCBI36
Build 341142,998,278 - 143,005,120NCBI
Celera1119,713,173 - 119,719,433 (-)NCBICelera
Cytogenetic Map1q21.1NCBI
HuRef1119,473,510 - 119,479,770 (-)NCBIHuRef
CHM1_11147,287,139 - 147,293,399 (+)NCBICHM1_1
T2T-CHM13v2.01145,035,832 - 145,042,160 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in GNRHR2
117 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 3 3 5 1 22 2 3 3
Below cutoff 1 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: NM_001001639   ⟹   NP_001001639
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1499,410,366 - 99,414,848 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021088735   ⟹   XP_020944394
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1499,409,569 - 99,415,346 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021088736   ⟹   XP_020944395
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1499,409,569 - 99,415,134 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020944394   ⟸   XM_021088735
- Peptide Label: isoform X1
- UniProtKB: I3RLD1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020944395   ⟸   XM_021088736
- Peptide Label: isoform X2
- UniProtKB: A0A4X1SJL3 (UniProtKB/TrEMBL),   F1SDF2 (UniProtKB/TrEMBL),   F1SDF3 (UniProtKB/TrEMBL),   A0A8D1IKP2 (UniProtKB/TrEMBL),   A0A8D0Y6L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001001639   ⟸   NM_001001639
- UniProtKB: Q6QGW2 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006685 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005024405 UniProtKB/TrEMBL
  ENSSSCG00015038215 UniProtKB/TrEMBL
  ENSSSCG00025068533 UniProtKB/TrEMBL
  ENSSSCG00030070274 UniProtKB/TrEMBL
  ENSSSCG00035070316 UniProtKB/TrEMBL
  ENSSSCG00040051020 UniProtKB/TrEMBL
  ENSSSCG00045030906 UniProtKB/TrEMBL
  ENSSSCG00050074711 UniProtKB/TrEMBL
  ENSSSCG00055027810 UniProtKB/TrEMBL
  ENSSSCG00060026560 UniProtKB/TrEMBL
  ENSSSCG00065000864 UniProtKB/TrEMBL
  ENSSSCG00070001637 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007323 ENTREZGENE
  ENSSSCT00000007323.4 UniProtKB/TrEMBL
  ENSSSCT00000007324.4 UniProtKB/TrEMBL
  ENSSSCT00005038765.1 UniProtKB/TrEMBL
  ENSSSCT00005038822.1 UniProtKB/TrEMBL
  ENSSSCT00015050965.1 UniProtKB/TrEMBL
  ENSSSCT00015051025.1 UniProtKB/TrEMBL
  ENSSSCT00025094188.1 UniProtKB/TrEMBL
  ENSSSCT00025094278.1 UniProtKB/TrEMBL
  ENSSSCT00030098293.1 UniProtKB/TrEMBL
  ENSSSCT00030098316.1 UniProtKB/TrEMBL
  ENSSSCT00035095021.1 UniProtKB/TrEMBL
  ENSSSCT00035095037.1 UniProtKB/TrEMBL
  ENSSSCT00040069187.1 UniProtKB/TrEMBL
  ENSSSCT00040069288.1 UniProtKB/TrEMBL
  ENSSSCT00040069336.1 UniProtKB/TrEMBL
  ENSSSCT00045052706.1 UniProtKB/TrEMBL
  ENSSSCT00045052772.1 UniProtKB/TrEMBL
  ENSSSCT00050102277.1 UniProtKB/TrEMBL
  ENSSSCT00050102279.1 UniProtKB/TrEMBL
  ENSSSCT00055055091.1 UniProtKB/TrEMBL
  ENSSSCT00055055130.1 UniProtKB/TrEMBL
  ENSSSCT00055055162.1 UniProtKB/TrEMBL
  ENSSSCT00060035950.1 UniProtKB/TrEMBL
  ENSSSCT00060035952.1 UniProtKB/TrEMBL
  ENSSSCT00065001025.1 UniProtKB/TrEMBL
  ENSSSCT00065001030.1 UniProtKB/TrEMBL
  ENSSSCT00070003058.1 UniProtKB/TrEMBL
  ENSSSCT00070003075.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  GphnRH_fam_rcpt UniProtKB/TrEMBL
KEGG Report ssc:414423 UniProtKB/TrEMBL
NCBI Gene GNRHR2 ENTREZGENE
PANTHER NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  PTHR24241:SF69 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GNADOTRPHINR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A4X1SJB7_PIG UniProtKB/TrEMBL
  A0A4X1SJL3 ENTREZGENE
  A0A8D0T4P8_PIG UniProtKB/TrEMBL
  A0A8D0Y6L9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1F3X7_PIG UniProtKB/TrEMBL
  A0A8D1IKP2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1IUY0_PIG UniProtKB/TrEMBL
  F1SDF2 ENTREZGENE
  F1SDF3 ENTREZGENE, UniProtKB/TrEMBL
  I3RLD1 ENTREZGENE, UniProtKB/TrEMBL
  Q6QGW2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1SJL3 UniProtKB/TrEMBL
  A0A5K1VJL9 UniProtKB/TrEMBL
  F1SDF2 UniProtKB/TrEMBL
VGNC ID VGNC:109150 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-28 GNRHR2  gonadotropin releasing hormone receptor 2  GNRHR2  gonadotropin-releasing hormone (type 2) receptor 2  Symbol and/or name change 19259463 PROVISIONAL