KLHL36 (kelch like family member 36) - Rat Genome Database

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Gene: KLHL36 (kelch like family member 36) Sus scrofa
Analyze
Symbol: KLHL36
Name: kelch like family member 36
RGD ID: 13950565
Description: ENCODES a protein that exhibits cullin family protein binding (inferred); INVOLVED IN protein ubiquitination (inferred); ASSOCIATED WITH genetic disease (ortholog); persistent fetal circulation syndrome (ortholog); schizophrenia (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kelch-like protein 36
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl64,067,403 - 4,080,075 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.164,062,563 - 4,080,183 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
KLHL36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl64,067,403 - 4,080,075 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.164,062,563 - 4,080,183 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KLHL36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381684,648,511 - 84,667,686 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1684,648,511 - 84,667,686 (+)EnsemblGRCh38hg38GRCh38
GRCh371684,682,117 - 84,701,292 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361683,239,632 - 83,253,417 (+)NCBINCBI36Build 36hg18NCBI36
Build 341683,239,631 - 83,253,416NCBI
Celera1668,984,322 - 68,998,096 (+)NCBICelera
Cytogenetic Map16q24.1NCBI
HuRef1670,435,069 - 70,448,923 (+)NCBIHuRef
CHM1_11686,093,710 - 86,107,492 (+)NCBICHM1_1
T2T-CHM13v2.01690,714,793 - 90,733,970 (+)NCBIT2T-CHM13v2.0
Klhl36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,588,970 - 120,603,728 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8120,589,005 - 120,603,734 (+)EnsemblGRCm39 Ensembl
GRCm388119,862,231 - 119,876,989 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8119,862,266 - 119,876,995 (+)EnsemblGRCm38mm10GRCm38
MGSCv378122,386,205 - 122,400,889 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368122,748,282 - 122,762,966 (+)NCBIMGSCv36mm8
Celera8124,078,901 - 124,093,589 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map868.52NCBI
Klhl36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,830,218 - 64,851,251 (+)NCBIGRCr8
mRatBN7.21947,921,590 - 47,942,627 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,921,590 - 47,942,620 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1954,715,923 - 54,736,945 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01955,396,664 - 55,417,692 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,609,612 - 57,630,578 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,515,022 - 52,536,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,515,022 - 52,536,476 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01963,259,151 - 63,280,351 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41950,145,835 - 50,166,861 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1947,178,205 - 47,199,290 (+)NCBICelera
Cytogenetic Map19q12NCBI
Klhl36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955541205,170 - 219,164 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955541205,170 - 218,943 (+)NCBIChiLan1.0ChiLan1.0
KLHL36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21894,396,499 - 94,417,355 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116100,313,658 - 100,334,489 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01665,314,253 - 65,335,194 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11684,656,009 - 84,676,221 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1684,656,009 - 84,670,664 (+)Ensemblpanpan1.1panPan2
KLHL36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1567,828,301 - 67,854,113 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl567,832,694 - 67,846,013 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha567,842,892 - 67,868,693 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0568,061,929 - 68,087,690 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl568,066,701 - 68,077,131 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1568,076,370 - 68,102,190 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0567,911,501 - 67,937,143 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0568,326,142 - 68,351,975 (-)NCBIUU_Cfam_GSD_1.0
Klhl36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934927,638,706 - 27,658,171 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366413,388,887 - 3,403,581 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366413,392,253 - 3,403,575 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1570,050,442 - 70,064,859 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl570,050,757 - 70,064,682 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660475,680,033 - 5,699,789 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl36
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247461,526,185 - 1,539,525 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KLHL36
503 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000055545   ⟹   ENSSSCP00000040128
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl64,067,403 - 4,080,075 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000073968   ⟹   ENSSSCP00000071019
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl64,066,714 - 4,079,863 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000075944   ⟹   ENSSSCP00000069187
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl64,067,515 - 4,080,075 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000077630   ⟹   ENSSSCP00000062950
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl64,067,393 - 4,079,863 (-)Ensembl
RefSeq Acc Id: XM_021093726   ⟹   XP_020949385
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.164,062,563 - 4,080,183 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020949385   ⟸   XM_021093726
- UniProtKB: A0A480P5C1 (UniProtKB/TrEMBL),   A0A287A862 (UniProtKB/TrEMBL),   A0A480YWF8 (UniProtKB/TrEMBL),   A0A4X1T616 (UniProtKB/TrEMBL),   A0A8D1X708 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000071019   ⟸   ENSSSCT00000073968
RefSeq Acc Id: ENSSSCP00000069187   ⟸   ENSSSCT00000075944
RefSeq Acc Id: ENSSSCP00000040128   ⟸   ENSSSCT00000055545
RefSeq Acc Id: ENSSSCP00000062950   ⟸   ENSSSCT00000077630
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038285 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005034968 UniProtKB/TrEMBL
  ENSSSCG00015033899 UniProtKB/TrEMBL
  ENSSSCG00025051096 UniProtKB/TrEMBL
  ENSSSCG00030063900 UniProtKB/TrEMBL
  ENSSSCG00040008841 UniProtKB/TrEMBL
  ENSSSCG00045029890 UniProtKB/TrEMBL
  ENSSSCG00050030094 UniProtKB/TrEMBL
  ENSSSCG00055013103 UniProtKB/TrEMBL
  ENSSSCG00060035840 UniProtKB/TrEMBL
  ENSSSCG00065002751 UniProtKB/TrEMBL
  ENSSSCG00070006500 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000055545 ENTREZGENE
  ENSSSCT00000055545.3 UniProtKB/TrEMBL
  ENSSSCT00000075944.2 UniProtKB/TrEMBL
  ENSSSCT00005055866.1 UniProtKB/TrEMBL
  ENSSSCT00005055888.1 UniProtKB/TrEMBL
  ENSSSCT00015044981.1 UniProtKB/TrEMBL
  ENSSSCT00025069847.1 UniProtKB/TrEMBL
  ENSSSCT00030089403.1 UniProtKB/TrEMBL
  ENSSSCT00040011491.1 UniProtKB/TrEMBL
  ENSSSCT00045051034.1 UniProtKB/TrEMBL
  ENSSSCT00050040458.1 UniProtKB/TrEMBL
  ENSSSCT00055025840.1 UniProtKB/TrEMBL
  ENSSSCT00060048558.1 UniProtKB/TrEMBL
  ENSSSCT00065003620.1 UniProtKB/TrEMBL
  ENSSSCT00070012406.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
NCBI Gene KLHL36 ENTREZGENE
PANTHER LD33804P UniProtKB/TrEMBL
  PTHR45632:SF4 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  Kelch_5 UniProtKB/TrEMBL
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A287A862 ENTREZGENE
  A0A480P5C1 ENTREZGENE, UniProtKB/TrEMBL
  A0A480YWF8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1T616 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1IP74_PIG UniProtKB/TrEMBL
  A0A8D1X708 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287A862 UniProtKB/TrEMBL
  A0A5G2REB2 UniProtKB/TrEMBL
VGNC ID VGNC:89530 ENTREZGENE