DIDO1 (death inducer-obliterator 1) - Rat Genome Database

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Gene: DIDO1 (death inducer-obliterator 1) Sus scrofa
Analyze
Symbol: DIDO1
Name: death inducer-obliterator 1
RGD ID: 13945801
Description: ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN apoptotic signaling pathway (ortholog); ASSOCIATED WITH autosomal dominant nocturnal frontal lobe epilepsy (ortholog); benign familial infantile seizures 6 (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN nuclear lumen (inferred); nucleus (inferred); Set1C/COMPASS complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: death-inducer obliterator 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,125,122 - 62,174,071 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11762,126,026 - 62,174,095 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DIDO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,125,122 - 62,174,071 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11762,126,026 - 62,174,095 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DIDO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382062,877,743 - 62,937,904 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2062,877,738 - 62,937,952 (-)EnsemblGRCh38hg38GRCh38
GRCh372061,509,095 - 61,569,256 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362060,979,535 - 61,039,719 (-)NCBINCBI36Build 36hg18NCBI36
Build 342061,006,799 - 61,016,204NCBI
Celera2058,185,696 - 58,245,931 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2058,226,477 - 58,286,320 (-)NCBIHuRef
CHM1_12061,410,099 - 61,470,313 (-)NCBICHM1_1
T2T-CHM13v2.02064,677,856 - 64,738,018 (-)NCBIT2T-CHM13v2.0
Dido1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392180,299,757 - 180,351,886 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2180,299,757 - 180,351,792 (-)EnsemblGRCm39 Ensembl
GRCm382180,657,963 - 180,710,068 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2180,657,964 - 180,709,999 (-)EnsemblGRCm38mm10GRCm38
MGSCv372180,392,669 - 180,444,704 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362180,587,372 - 180,639,407 (-)NCBIMGSCv36mm8
Celera2184,743,521 - 184,795,531 (-)NCBICelera
Cytogenetic Map2H4NCBI
Dido1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,150,100 - 188,203,445 (-)NCBIGRCr8
mRatBN7.23167,772,535 - 167,825,894 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3167,772,770 - 167,817,218 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03176,162,886 - 176,216,868 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,162,886 - 176,197,753 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03179,862,994 - 179,915,916 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43169,773,804 - 169,797,391 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13169,650,732 - 169,691,373 (-)NCBI
Celera3164,756,972 - 164,810,015 (+)NCBICelera
Cytogenetic Map3q43NCBI
Dido1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555281,162,836 - 1,207,596 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555281,153,181 - 1,207,346 (+)NCBIChiLan1.0ChiLan1.0
DIDO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22168,664,981 - 68,725,218 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12068,658,100 - 68,718,337 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02059,264,759 - 59,325,092 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12060,556,923 - 60,617,265 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2060,556,923 - 60,617,265 (-)Ensemblpanpan1.1panPan2
DIDO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,691,117 - 46,735,117 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2446,692,605 - 46,724,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2445,875,276 - 45,924,685 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02447,563,695 - 47,612,949 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2447,565,190 - 47,612,947 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12446,661,345 - 46,710,760 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02446,784,621 - 46,833,858 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,540,618 - 47,590,068 (-)NCBIUU_Cfam_GSD_1.0
Dido1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640194,917,318 - 194,968,873 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651410,370,959 - 10,403,889 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651410,370,961 - 10,422,484 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DIDO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121,285,027 - 1,345,726 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21,285,051 - 1,345,846 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605049,114,402 - 49,175,884 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dido1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474128,646,938 - 28,700,683 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DIDO1
479 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000040552   ⟹   ENSSSCP00000043664
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1762,148,887 - 62,174,071 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000050346   ⟹   ENSSSCP00000043978
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1762,134,196 - 62,165,407 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000102889   ⟹   ENSSSCP00000078411
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1762,149,052 - 62,174,071 (-)Ensembl
RefSeq Acc Id: XM_021078224   ⟹   XP_020933883
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11762,126,026 - 62,174,095 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020933883 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000043664.2
  ENSSSCP00000043978.2
  ENSSSCP00000078411.1
  ENSSSCP00035006980.1
  ENSSSCP00035006986.1
  ENSSSCP00045024820.1
  ENSSSCP00050034051.1
  ENSSSCP00055017493.1
Reference Protein Sequences
RefSeq Acc Id: XP_020933883   ⟸   XM_021078224
- UniProtKB: A0A8D0YS40 (UniProtKB/TrEMBL),   A0A8D1N7W3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000043664   ⟸   ENSSSCT00000040552
RefSeq Acc Id: ENSSSCP00000043978   ⟸   ENSSSCT00000050346
RefSeq Acc Id: ENSSSCP00000078411   ⟸   ENSSSCT00000102889
Protein Domains
PHD-type   TFIIS central


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000033946 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00035015393 UniProtKB/TrEMBL
  ENSSSCG00045020851 UniProtKB/TrEMBL
  ENSSSCG00050058080 UniProtKB/TrEMBL
  ENSSSCG00055011226 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000040552.3 UniProtKB/TrEMBL
  ENSSSCT00000050346.3 UniProtKB/TrEMBL
  ENSSSCT00000102889.1 UniProtKB/TrEMBL
  ENSSSCT00035019604.1 UniProtKB/TrEMBL
  ENSSSCT00035019613.1 UniProtKB/TrEMBL
  ENSSSCT00045035713.1 UniProtKB/TrEMBL
  ENSSSCT00050079181.1 UniProtKB/TrEMBL
  ENSSSCT00055022091.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.472.30 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro DIDO1 UniProtKB/TrEMBL
  SPOC_C UniProtKB/TrEMBL
  Spp1/CFP1 UniProtKB/TrEMBL
  TFIIS_cen_dom UniProtKB/TrEMBL
  TFIIS_cen_dom_sf UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene DIDO1 ENTREZGENE
PANTHER AT26187P-RELATED UniProtKB/TrEMBL
  CXXC-TYPE ZINC FINGER PROTEIN 1 UniProtKB/TrEMBL
  PTHR11477:SF13 UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam PHD UniProtKB/TrEMBL
  SPOC UniProtKB/TrEMBL
  TFIIS_M UniProtKB/TrEMBL
PROSITE TFIIS_CENTRAL UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
SMART PHD UniProtKB/TrEMBL
  TFS2M UniProtKB/TrEMBL
Superfamily-SCOP SSF46942 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A287AIF6_PIG UniProtKB/TrEMBL
  A0A287AIZ5_PIG UniProtKB/TrEMBL
  A0A8D0YS40 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YV61_PIG UniProtKB/TrEMBL
  A0A8D1N7W3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FHQ6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:96141 ENTREZGENE