TRIM39 (tripartite motif containing 39)

Gene: TRIM39 (tripartite motif containing 39) Sus scrofa

Analyze

Symbol:

TRIM39

Name:

tripartite motif containing 39

RGD ID:

13944265

Description:

ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN mitotic G2 DNA damage checkpoint signaling (inferred); negative regulation of canonical NF-kappaB signal transduction (inferred); negative regulation of proteasomal ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); megacolon (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

tripartite motif-containing protein 39

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	23,047,520 - 23,062,487 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	23,047,048 - 23,062,974 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	26,716,866 - 26,733,939 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

megacolon (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mitotic G2 DNA damage checkpoint signaling (IEA)

negative regulation of canonical NF-kappaB signal transduction (IEA)

negative regulation of proteasomal ubiquitin-dependent protein catabolic process (IBA,IEA)

negative regulation of ubiquitin-dependent protein catabolic process (IEA)

positive regulation of apoptotic signaling pathway (IBA,IEA)

protein stabilization (IBA,IEA)

protein ubiquitination (IBA,IEA)

regulation of cell cycle G1/S phase transition (IEA)

Cellular Component

cytoplasm (IBA,IEA)

cytosol (IBA,IEA)

mitochondrion (IEA)

nucleus (IEA)

Molecular Function

identical protein binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

ubiquitin protein ligase activity (IBA,IEA)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:16328468	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

TRIM39
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	23,047,520 - 23,062,487 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	23,047,048 - 23,062,974 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	26,716,866 - 26,733,939 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRIM39
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	30,326,469 - 30,343,729 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	30,326,479 - 30,343,729 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	30,294,246 - 30,311,506 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	30,403,019 - 30,419,485 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	30,403,018 - 30,419,484	NCBI
Celera	6	31,892,811 - 31,909,701 (+)	NCBI		Celera
Cytogenetic Map	6	p22.1	NCBI
HuRef	6	30,092,745 - 30,109,636 (+)	NCBI		HuRef
CHM1_1	6	30,296,698 - 30,313,590 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	30,190,674 - 30,207,940 (+)	NCBI		T2T-CHM13v2.0

Trim39
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	36,569,764 - 36,582,896 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	36,569,765 - 36,583,139 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	36,258,872 - 36,272,004 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	36,258,873 - 36,272,247 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	36,395,818 - 36,408,949 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	35,866,925 - 35,880,057 (-)	NCBI		MGSCv36	mm8
Celera	17	39,731,391 - 39,744,522 (-)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	19.01	NCBI

Trim39
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	2,008,528 - 2,022,383 (+)	NCBI		GRCr8
mRatBN7.2	20	2,003,320 - 2,017,175 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	1,983,533 - 2,020,117 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	2,043,510 - 2,057,364 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	2,047,022 - 2,060,876 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	2,000,908 - 2,014,763 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	2,500,691 - 2,514,546 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	2,500,689 - 2,514,546 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	4,530,743 - 4,544,598 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	2,091,969 - 2,105,824 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	2,091,968 - 2,105,824 (+)	NCBI
Celera	20	2,710,987 - 2,724,842 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

TRIM39
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	44,919,935 - 44,937,249 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	40,882,956 - 40,900,270 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	30,104,381 - 30,121,649 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	30,975,260 - 30,992,628 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	30,975,260 - 30,995,764 (+)	Ensembl	panpan1.1		panPan2

Variants

Variants in TRIM39
460 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium
Low	10	4	3	5	2	23	2	3	3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001128479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005653455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013996585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB158488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AEMK02000053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AP009557	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU498826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01005924	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000001458 ⟹ ENSSSCP00000001416

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	23,050,195 - 23,064,498 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000086539 ⟹ ENSSSCP00000066831

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	23,047,520 - 23,062,487 (+)	Ensembl

RefSeq Acc Id:

NM_001128479 ⟹ NP_001121951

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	7	23,050,202 - 23,061,486 (+)	NCBI

Sequence:

show sequence

ATGGCAGAGACAAGTCTGTTAGAGGCCGGGGCCTCTGCAGCCTCCACAGCTGCAGCGCTGGAGA
ACTTACAGGTGGAGGCAAGTTGTTCTGTGTGCCTGGAGTATCTGAAGGAGCCTGTCATCATTGA
GTGTGGGCACAACTTCTGCAAAGCTTGCATCACCCGCTGGTGGGAGGACCTAGAGAGGGACTTC
CCTTGCCCTGTCTGTCGAAAGACATCCCGCTACCGCAGCCTCCGGCCTAATCGACAGCTGGGCA
GTATGGTGGAAATTGCCAAGCAGCTCCAAGCTGTCAAGCGGAAGATCCGAGATGAGAGCCTCTG
CCCCCAGCACCACGAGGCCCTCAGCCTCTTCTGCTATGAGGACCAGGAGGCTGTCTGTTTGATA
TGTGCAATTTCCCACACTCACCGGGCCCATACCGTTGTGCCACTGGATGATGCCACCCAGGAGT
ACAAGGAAAAACTGCAGAAGTGCCTGGAGCCCCTGGAGCAGAAGCTACAGGAGATCACCCGCTG
CAAGTCCTCTGAGGAGAAGAAGCCTGGCGAACTCAAGAGGCTAGTGGAGAGTCGCCGACAGCAG
ATCCTAAAGGAATTTGAAGAGCTTCATCGGCGGCTGGATGAAGAGCAGCAGGTGTTGCTTTCAC
GACTGGAGGAGGAGGAACAGGACATTCTTCAGCGCCTCCGAGAAAACGCTGCTCACCTTGGAGA
CAAGCGCCGGGACCTGGCCCACTTGGCTGCGGAGGTGGAGGGCAAGTGCTTACAGTCGGGCTTC
GAGATGCTTAAGGATGTCAAAAGTACCCTGGAAAAATGTGAGAAGGTGAAGACCATGGAGGTGA
CTTCAGTGTCAATAGAGCTGGAAAAGAACTTCAGCAATTTCCCCCGACAGTACTTTGCCCTAAG
GAAAATCCTTAAACAGCTAATTGCGGATGTGACCCTGGACCCCGAGACTGCTCATCCTAACCTA
GTCCTGTCGGAGGACCGTAAGAGCGTCAAGTTTGTGGAGACGAGACTCCGGGATCTCCCTGATA
CACCTCGGCGTTTCACCTTCTACCCTTGCGTCCTGGCCACTGAGGGCTTCACCTCAGGTCGACA
CTACTGGGAGGTGGAGGTGGGCGACAAGACCCACTGGGCCGTGGGTGTGTGCCGGGACTCTGTG
AGCCGGAAGGGCGAGCTGACCCCACTCCCTGAGACTGGCTACTGGCGGGTGCGGCTGTGGAACG
GCGACAAGTATGCAGCCACCACCACGCCTTTTACCCCTTTGCACATCAAGGTGAAACCCAAGCG
GGTGGGCATATTCCTAGACTATGAGGCCGGCACACTGTCTTTTTATAACGTCACAGACCGCTCT
CACATCTACACCTTCACCGATACTTTTACTGAAAAACTTTGGCCCCTCTTCTACCCAGGCATCC
GGGCTGGTCGGAAGAATGCTGCACCATTGACCATCAGACCCCCAACAGATTGGGAGTGA

hide sequence

RefSeq Acc Id:

XM_005653455 ⟹ XP_005653512

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	7	23,047,491 - 23,062,974 (+)	NCBI

Sequence:

show sequence

GTCGCGCTGCGGGGCGGGGGCGGGGGGAGGAGGAAGGAGGGAGGCAGCGCTCCGGCGGCTCCGC
GCCCCGCACTCCCGGACCCGAAGCCGGGAAGTTAAATAATGGCAGAGACAAGTCTGTTAGAGGC
CGGGGCCTCTGCAGCCTCCACAGCTGCAGCGCTGGAGAACTTACAGGTGGAGGCAAGTTGTTCT
GTGTGCCTGGAGTATCTGAAGGAGCCTGTCATCATTGAGTGTGGGCACAACTTCTGCAAAGCTT
GCATCACCCGCTGGTGGGAGGACCTAGAGAGGGACTTCCCTTGCCCTGTCTGTCGAAAGACATC
CCGCTACCGCAGCCTCCGGCCTAATCGACAGCTGGGCAGTATGGTGGAAATTGCCAAGCAGCTC
CAAGCTGTCAAGCGGAAGATCCGAGATGAGAGCCTCTGCCCCCAGCACCACGAGGCCCTCAGCC
TCTTCTGCTATGAGGACCAGGAGGCTGTCTGTTTGATATGTGCAATTTCCCACACTCACCGGGC
CCATACCGTTGTGCCACTGGATGATGCCACCCAGGAGTACAAGGAAAAACTGCAGAAGTGCCTG
GAGCCCCTGGAGCAGAAGCTACAGGAGATCACCCGCTGCAAGTCCTCTGAGGAGAAGAAGCCTG
GCGAACTCAAGAGGCTAGTGGAGAGTCGCCGACAGCAGATCCTAAAGGAATTTGAAGAGCTTCA
TCGGCGGCTGGATGAAGAGCAGCAGGTGTTGCTTTCACGACTGGAGGAGGAGGAACAGGACATT
CTTCAGCGCCTCCGAGAAAACGCTGCTCACCTTGGAGATAAGCGCCGGGACCTGGCCCACTTGG
CTGCGGAGGTGGAGGGCAAGTGCTTACAGTCGGGCTTCGAGATGCTTAAGGATGTCAAAAGTAC
CCTGGAAAAATGTGAGAAGGTGAAGACCATGGAGGTGACTTCAGTGTCAATAGAGCTGGAAAAG
AACTTCAGCAATTTCCCCCGACAGTACTTTGCCCTAAGGAAAATCCTTAAACAGCTAATTGCGG
ATGTGACCCTGGACCCCGAGACTGCTCATCCTAACCTAGTCCTGTCGGAGGACCGTAAGAGCGT
CAAGTTTGTGGAGACGAGACTCCGGGATCTCCCTGATACACCTCGGCGTTTCACCTTCTACCCT
TGCGTCCTGGCCACTGAGGGCTTCACCTCAGGTCGACACTACTGGGAGGTGGAGGTGGGCGACA
AGACCCACTGGGCCGTGGGTGTGTGCCGGGACTCTGTGAGCCGGAAGGGCGAGCTGACCCCACT
CCCTGAGACTGGCTACTGGCGGGTGCGGCTGTGGAACGGCGACAAGTATGCAGCCACCACCACG
CCTTTTACCCCTTTGCACATCAAGGTGAAACCCAAGCGGGTGGGCATATTCCTAGACTATGAGG
CCGGCACACTGTCTTTTTATAACGTCACAGACCGCTCTCACATCTACACCTTCACCGATACTTT
TACTGAAAAACTTTGGCCCCTCTTCTACCCAGGCATCCGGGCTGGTCGGAAGAATGCTGCACCA
TTGACCATCAGACCCCCAACAGATTGGGAGTGACAGGTAGGGACATGGGAATAATCAGGGTGAG
GCAGGGTCAAGAGCTACGGGCCTTCCTTCCTGTGACCTGCTGGAGCGTCTTCATGTCTGCTGGT
TCCAGTCCTGAACCATCTGGGAGAACACCATGGTTTCTAGAATGGTTTATGTGGAGGAGTAGGT
AGGACTGGGCTGGGACGAGAGCACGCTGTGTCTCCCTCCTAACTGTCAGGGTGGGGAGCTGGTT
CCCAGGGGGTTGTCGCCCCTGAAGTCCATCAGGTTTTCTGTTGCACAGGATGGGTTGGGAAGGA
AGGAGAGGCTTTTCCAGAAACAACAAGTCTATAGGAGGGTCTGACTTGCTCGAGTCAGAGGAGG
AAACCAAAACCCCTGTACATCCTTTTAGGGGGTTTCTTTGACCCAGAATGGTCTGGTTTCTTTA
GGAAGATCACAGGGGTCTCTGTACCTCTAGACTGAAATTAAGTTGAATGACAGTTGCTCTCGTG
GGTCTAGAAGTTGAGGAGTTTTGTTCAGGGCAGAGATTGGGCATCAAGGTTAGAAAGAAGGTTT
AAAAAAAAAGAGCTAGAAGGTTAAAAAAAAAAAAACTTAAGAAAGAAGGTTAGGAAAGGGGGCT
AAAGAAACAGATTCCTAAAGACTGCTGAAGAGAAGAGTGGCTTTGGTTGCCATCATGGGTAGGA
CTGACCGGAGGTAGGAATGCGGGGAAGAAAGAGAACCCAGGTCTCTGCCTCAGCCTTCAGCAGA
GCTGGCTTATCACCTGCCTCCTTGTAGTTGCTCGTCTCTAAGAGCTGTTACCTTGCTCATCTGG
AGAGGCAAGGTGCAGGAGCTCCTGCAAGACGTGTCTACCCCTTCACTGCTTTCCCAACCTGGAG
AGGAGAGAGTCAGGTATTAGAAGAAAGAGAAAAGTATTCCTATCCAAAGCCCCTGCCTTAAAGA
ATGCTACTGAGTAGCTGCTCCCAAGTTGTCAGCCTTGTTACCTGGCTAAGGTGTCCAAGCTGGA
CGGGGGAAAGAAAATGGAGTCTTCCTCACCCTGGGACAGGGTAGAAGGGGGTGGTATGTATAGG
GAAGGGCCAGATAGGCAACTTCCTTTGGCCTGTGTGCATATGGCCTGGAACTAGTGTTCACAAG
AGCCAATTTTTTTGCTTGTTTGTTGCCATCCTTCACCTTTTGCCATTTCTCCTATCAGAGAATG
TAAGTCATTTTTATGTTAGGCCAAAATAAACAAACTGTAGGGTACATATGTTGTCAAAAAAGGT
AAAGCAATGCATGCCAAACCAAACTAAAATGACTGGATTATCTGCTACTTGGGTAATCAGGGGT
TCACTGAAGATTAGGATAAGAAACTGCAGTTTATTGAGGGCATTTCAGCTCCTCCTACCACCTC
AACAGGACTTTGTCCAGACTCTCCTCTTACCTTTGTGCCTTGACTGTGGTTCTTTGTGGCAAGA
TGCTTTGGTTGGTAAAACAAAATATGGAACAAAGGATCCACTGAAGTGA

hide sequence

RefSeq Acc Id:

XM_013996585 ⟹ XP_013852039

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	7	23,047,048 - 23,062,974 (+)	NCBI

Sequence:

show sequence

CGAGCCACCTTCCCCCGGGCCGGCTTGGAGAGAAGTGTAGCTCAAAGTCCGCAACTCGCCCTTG
CCCCGCCCCCGGCGGCTCCCAGCCCCACCCGGGACTAGGCGAGCCAGGAGAGAGCCCTGGCCCT
CACCCTGTCCGGGTCTCGCCCACCCGGGCGCGGATAGGCGCCTGAGGGCAATGGGCTTCAGCGC
TCCGCCGCGCGCATGCGCGGTCCTCTTTTCCCAGAGGATTCCTCGGATCACCTGGACGACCGCA
TTTCAGCTACCTGTCCCTCCGGGTCCCTTCTCGCCCTTGACTCCTCCTGCTGGTTCTCACCTCC
ATCCCCCAGCCTTCTCCTTCTTCCGCAGGCGTCGCTAGGCCCTCCCGCGGCCGCCCGCCGACAC
CCCGGCTTCCACTGACACGAGCCTCTCGGCGTGGCTTCCGCTTCCGTTAAATAATGGCAGAGAC
AAGTCTGTTAGAGGCCGGGGCCTCTGCAGCCTCCACAGCTGCAGCGCTGGAGAACTTACAGGTG
GAGGCAAGTTGTTCTGTGTGCCTGGAGTATCTGAAGGAGCCTGTCATCATTGAGTGTGGGCACA
ACTTCTGCAAAGCTTGCATCACCCGCTGGTGGGAGGACCTAGAGAGGGACTTCCCTTGCCCTGT
CTGTCGAAAGACATCCCGCTACCGCAGCCTCCGGCCTAATCGACAGCTGGGCAGTATGGTGGAA
ATTGCCAAGCAGCTCCAAGCTGTCAAGCGGAAGATCCGAGATGAGAGCCTCTGCCCCCAGCACC
ACGAGGCCCTCAGCCTCTTCTGCTATGAGGACCAGGAGGCTGTCTGTTTGATATGTGCAATTTC
CCACACTCACCGGGCCCATACCGTTGTGCCACTGGATGATGCCACCCAGGAGTACAAGGAAAAA
CTGCAGAAGTGCCTGGAGCCCCTGGAGCAGAAGCTACAGGAGATCACCCGCTGCAAGTCCTCTG
AGGAGAAGAAGCCTGGCGAACTCAAGAGGCTAGTGGAGAGTCGCCGACAGCAGATCCTAAAGGA
ATTTGAAGAGCTTCATCGGCGGCTGGATGAAGAGCAGCAGGTGTTGCTTTCACGACTGGAGGAG
GAGGAACAGGACATTCTTCAGCGCCTCCGAGAAAACGCTGCTCACCTTGGAGATAAGCGCCGGG
ACCTGGCCCACTTGGCTGCGGAGGTGGAGGGCAAGTGCTTACAGTCGGGCTTCGAGATGCTTAA
GGATGTCAAAAGTACCCTGGAAAAATGTGAGAAGGTGAAGACCATGGAGGTGACTTCAGTGTCA
ATAGAGCTGGAAAAGAACTTCAGCAATTTCCCCCGACAGTACTTTGCCCTAAGGAAAATCCTTA
AACAGCTAATTGCGGATGTGACCCTGGACCCCGAGACTGCTCATCCTAACCTAGTCCTGTCGGA
GGACCGTAAGAGCGTCAAGTTTGTGGAGACGAGACTCCGGGATCTCCCTGATACACCTCGGCGT
TTCACCTTCTACCCTTGCGTCCTGGCCACTGAGGGCTTCACCTCAGGTCGACACTACTGGGAGG
TGGAGGTGGGCGACAAGACCCACTGGGCCGTGGGTGTGTGCCGGGACTCTGTGAGCCGGAAGGG
CGAGCTGACCCCACTCCCTGAGACTGGCTACTGGCGGGTGCGGCTGTGGAACGGCGACAAGTAT
GCAGCCACCACCACGCCTTTTACCCCTTTGCACATCAAGGTGAAACCCAAGCGGGTGGGCATAT
TCCTAGACTATGAGGCCGGCACACTGTCTTTTTATAACGTCACAGACCGCTCTCACATCTACAC
CTTCACCGATACTTTTACTGAAAAACTTTGGCCCCTCTTCTACCCAGGCATCCGGGCTGGTCGG
AAGAATGCTGCACCATTGACCATCAGACCCCCAACAGATTGGGAGTGACAGGTAGGGACATGGG
AATAATCAGGGTGAGGCAGGGTCAAGAGCTACGGGCCTTCCTTCCTGTGACCTGCTGGAGCGTC
TTCATGTCTGCTGGTTCCAGTCCTGAACCATCTGGGAGAACACCATGGTTTCTAGAATGGTTTA
TGTGGAGGAGTAGGTAGGACTGGGCTGGGACGAGAGCACGCTGTGTCTCCCTCCTAACTGTCAG
GGTGGGGAGCTGGTTCCCAGGGGGTTGTCGCCCCTGAAGTCCATCAGGTTTTCTGTTGCACAGG
ATGGGTTGGGAAGGAAGGAGAGGCTTTTCCAGAAACAACAAGTCTATAGGAGGGTCTGACTTGC
TCGAGTCAGAGGAGGAAACCAAAACCCCTGTACATCCTTTTAGGGGGTTTCTTTGACCCAGAAT
GGTCTGGTTTCTTTAGGAAGATCACAGGGGTCTCTGTACCTCTAGACTGAAATTAAGTTGAATG
ACAGTTGCTCTCGTGGGTCTAGAAGTTGAGGAGTTTTGTTCAGGGCAGAGATTGGGCATCAAGG
TTAGAAAGAAGGTTTAAAAAAAAAGAGCTAGAAGGTTAAAAAAAAAAAAACTTAAGAAAGAAGG
TTAGGAAAGGGGGCTAAAGAAACAGATTCCTAAAGACTGCTGAAGAGAAGAGTGGCTTTGGTTG
CCATCATGGGTAGGACTGACCGGAGGTAGGAATGCGGGGAAGAAAGAGAACCCAGGTCTCTGCC
TCAGCCTTCAGCAGAGCTGGCTTATCACCTGCCTCCTTGTAGTTGCTCGTCTCTAAGAGCTGTT
ACCTTGCTCATCTGGAGAGGCAAGGTGCAGGAGCTCCTGCAAGACGTGTCTACCCCTTCACTGC
TTTCCCAACCTGGAGAGGAGAGAGTCAGGTATTAGAAGAAAGAGAAAAGTATTCCTATCCAAAG
CCCCTGCCTTAAAGAATGCTACTGAGTAGCTGCTCCCAAGTTGTCAGCCTTGTTACCTGGCTAA
GGTGTCCAAGCTGGACGGGGGAAAGAAAATGGAGTCTTCCTCACCCTGGGACAGGGTAGAAGGG
GGTGGTATGTATAGGGAAGGGCCAGATAGGCAACTTCCTTTGGCCTGTGTGCATATGGCCTGGA
ACTAGTGTTCACAAGAGCCAATTTTTTTGCTTGTTTGTTGCCATCCTTCACCTTTTGCCATTTC
TCCTATCAGAGAATGTAAGTCATTTTTATGTTAGGCCAAAATAAACAAACTGTAGGGTACATAT
GTTGTCAAAAAAGGTAAAGCAATGCATGCCAAACCAAACTAAAATGACTGGATTATCTGCTACT
TGGGTAATCAGGGGTTCACTGAAGATTAGGATAAGAAACTGCAGTTTATTGAGGGCATTTCAGC
TCCTCCTACCACCTCAACAGGACTTTGTCCAGACTCTCCTCTTACCTTTGTGCCTTGACTGTGG
TTCTTTGTGGCAAGATGCTTTGGTTGGTAAAACAAAATATGGAACAAAGGATCCACTGAAGTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001121951	(Get FASTA)	NCBI Sequence Viewer
	XP_005653512	(Get FASTA)	NCBI Sequence Viewer
	XP_013852039	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAD83393	(Get FASTA)	NCBI Sequence Viewer
	BAG82705	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000066831
	ENSSSCP00000066831.1
	ENSSSCP00005010390.1
	ENSSSCP00005010403.1
	ENSSSCP00005010410.1
	ENSSSCP00015019803.1
	ENSSSCP00015019885.1
	ENSSSCP00015019908.1
	ENSSSCP00025012684.1
	ENSSSCP00030040629.1
	ENSSSCP00035037257.1
	ENSSSCP00035037278.1
	ENSSSCP00035037303.1
	ENSSSCP00040044868.1
	ENSSSCP00045048912.1
	ENSSSCP00050008804.1
	ENSSSCP00055049073.1
	ENSSSCP00055049074.1
	ENSSSCP00055049075.1
	ENSSSCP00060031314.1
	ENSSSCP00060031317.1
	ENSSSCP00060031320.1
	ENSSSCP00065037515.1
	ENSSSCP00065037523.1
	ENSSSCP00065037528.1
	ENSSSCP00070041621.1
	ENSSSCP00070041622.1
	ENSSSCP00070041624.1

RefSeq Acc Id:	XP_013852039 ⟸ XM_013996585
- Peptide Label:	isoform X1
- UniProtKB:	I7FTT9 (UniProtKB/TrEMBL), A0A4X1VII7 (UniProtKB/TrEMBL), A0A8D1LIA9 (UniProtKB/TrEMBL), A0A8D0XWX9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDF PCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLI CAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQ ILKEFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGF EMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNL VLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSV SRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRS HIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE hide sequence

RefSeq Acc Id:	XP_005653512 ⟸ XM_005653455
- Peptide Label:	isoform X1
- UniProtKB:	I7FTT9 (UniProtKB/TrEMBL), A0A4X1VII7 (UniProtKB/TrEMBL), A0A8D1LIA9 (UniProtKB/TrEMBL), A0A8D0XWX9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDF PCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLI CAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQ ILKEFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGF EMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNL VLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSV SRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRS HIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE hide sequence

RefSeq Acc Id:

NP_001121951 ⟸ NM_001128479

- UniProtKB:

I7FTT9 (UniProtKB/TrEMBL), A0A4X1VII7 (UniProtKB/TrEMBL), A0A8D1LIA9 (UniProtKB/TrEMBL), A0A8D0XWX9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDF
PCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLI
CAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQ
ILKEFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGF
EMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNL
VLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSV
SRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRS
HIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE

hide sequence

RefSeq Acc Id:

ENSSSCP00000001416 ⟸ ENSSSCT00000001458

RefSeq Acc Id:

ENSSSCP00000066831 ⟸ ENSSSCT00000086539

Protein Domains

B box-type B30.2/SPRY RING-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000001342	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005011301	UniProtKB/TrEMBL
	ENSSSCG00015037086	UniProtKB/TrEMBL
	ENSSSCG00025021930	UniProtKB/TrEMBL
	ENSSSCG00030062827	UniProtKB/TrEMBL
	ENSSSCG00035066163	UniProtKB/TrEMBL
	ENSSSCG00040072562	UniProtKB/TrEMBL
	ENSSSCG00045039438	UniProtKB/TrEMBL
	ENSSSCG00050015590	UniProtKB/TrEMBL
	ENSSSCG00055030689	UniProtKB/TrEMBL
	ENSSSCG00060053262	UniProtKB/TrEMBL
	ENSSSCG00065062551	UniProtKB/TrEMBL
	ENSSSCG00070024680	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000086539	ENTREZGENE
	ENSSSCT00000086539.2	UniProtKB/TrEMBL
	ENSSSCT00005017391.1	UniProtKB/TrEMBL
	ENSSSCT00005017416.1	UniProtKB/TrEMBL
	ENSSSCT00005017425.1	UniProtKB/TrEMBL
	ENSSSCT00015049695.1	UniProtKB/TrEMBL
	ENSSSCT00015049838.1	UniProtKB/TrEMBL
	ENSSSCT00015049885.1	UniProtKB/TrEMBL
	ENSSSCT00025029841.1	UniProtKB/TrEMBL
	ENSSSCT00030087918.1	UniProtKB/TrEMBL
	ENSSSCT00035089160.1	UniProtKB/TrEMBL
	ENSSSCT00035089219.1	UniProtKB/TrEMBL
	ENSSSCT00035089272.1	UniProtKB/TrEMBL
	ENSSSCT00040099947.1	UniProtKB/TrEMBL
	ENSSSCT00045068701.1	UniProtKB/TrEMBL
	ENSSSCT00050021097.1	UniProtKB/TrEMBL
	ENSSSCT00055061194.1	UniProtKB/TrEMBL
	ENSSSCT00055061195.1	UniProtKB/TrEMBL
	ENSSSCT00055061196.1	UniProtKB/TrEMBL
	ENSSSCT00060072555.1	UniProtKB/TrEMBL
	ENSSSCT00060072564.1	UniProtKB/TrEMBL
	ENSSSCT00060072567.1	UniProtKB/TrEMBL
	ENSSSCT00065085820.1	UniProtKB/TrEMBL
	ENSSSCT00065085837.1	UniProtKB/TrEMBL
	ENSSSCT00065085848.1	UniProtKB/TrEMBL
	ENSSSCT00070049270.1	UniProtKB/TrEMBL
	ENSSSCT00070049271.1	UniProtKB/TrEMBL
	ENSSSCT00070049272.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.920	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	B30.2/SPRY	UniProtKB/TrEMBL
	B30.2/SPRY_sf	UniProtKB/TrEMBL
	Butyrophylin_SPRY	UniProtKB/TrEMBL
	ConA-like_dom_sf	UniProtKB/TrEMBL
	PRY	UniProtKB/TrEMBL
	PRY/SPRY_TRIM39	UniProtKB/TrEMBL
	SPRY_dom	UniProtKB/TrEMBL
	Znf_B-box	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
KEGG Report	ssc:100151742	UniProtKB/TrEMBL
NCBI Gene	TRIM39	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE TRIM	UniProtKB/TrEMBL
	E3 UBIQUITIN-PROTEIN LIGASE TRIM39	UniProtKB/TrEMBL
Pfam	PRY	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
	zf-B_box	UniProtKB/TrEMBL
	zf-C3HC4_4	UniProtKB/TrEMBL
PRINTS	BUTYPHLNCDUF	UniProtKB/TrEMBL
PROSITE	B302_SPRY	UniProtKB/TrEMBL
	ZF_BBOX	UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
SMART	BBOX	UniProtKB/TrEMBL
	PRY	UniProtKB/TrEMBL
	RING	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
Superfamily-SCOP	B-box zinc-binding domain	UniProtKB/TrEMBL
	RING/U-box	UniProtKB/TrEMBL
	SSF49899	UniProtKB/TrEMBL
UniProt	A0A4X1VII7	ENTREZGENE
	A0A8D0XWX9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1LIA9	ENTREZGENE, UniProtKB/TrEMBL
	B6ICX0_PIG	UniProtKB/TrEMBL
	I7FTT9	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A4X1VII7	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar