ARHGAP32 (Rho GTPase activating protein 32) - Rat Genome Database

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Gene: ARHGAP32 (Rho GTPase activating protein 32) Sus scrofa
Analyze
Symbol: ARHGAP32
Name: Rho GTPase activating protein 32
RGD ID: 13936437
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); phosphatidylinositol binding (inferred); phosphatidylinositol phosphate binding (inferred); INVOLVED IN cerebellum development (ortholog); positive regulation of axon extension (ortholog); positive regulation of neuron migration (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); FOUND IN actin cytoskeleton (inferred); cell cortex (inferred); fibrillar center (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GTPase-activating protein 32
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl955,906,954 - 56,177,551 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1955,903,365 - 56,177,639 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2961,997,185 - 62,009,623 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARHGAP32
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl955,906,954 - 56,177,551 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1955,903,365 - 56,177,639 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2961,997,185 - 62,009,623 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP32
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811128,965,060 - 129,279,632 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11128,965,060 - 129,279,324 (-)EnsemblGRCh38hg38GRCh38
GRCh3711128,834,955 - 129,149,413 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611128,343,052 - 128,399,222 (-)NCBINCBI36Build 36hg18NCBI36
Celera11126,003,454 - 126,230,572 (-)NCBICelera
Cytogenetic Map11q24.3NCBI
HuRef11124,785,776 - 125,014,078 (-)NCBIHuRef
CHM1_111128,721,150 - 128,948,156 (-)NCBICHM1_1
T2T-CHM13v2.011128,999,975 - 129,315,124 (-)NCBIT2T-CHM13v2.0
Arhgap32
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39931,927,921 - 32,176,061 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl932,027,432 - 32,179,742 (+)EnsemblGRCm39 Ensembl
GRCm38932,016,625 - 32,268,443 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl932,116,136 - 32,268,446 (+)EnsemblGRCm38mm10GRCm38
MGSCv37931,923,721 - 32,072,084 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36931,957,765 - 32,010,849 (+)NCBIMGSCv36mm8
Celera929,377,749 - 29,526,489 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map917.48NCBI
Arhgap32
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8838,679,368 - 38,939,960 (+)NCBIGRCr8
mRatBN7.2830,421,269 - 30,681,653 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl830,421,515 - 30,678,454 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0833,131,874 - 33,392,198 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl833,239,139 - 33,392,305 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0833,168,863 - 33,409,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4831,859,986 - 32,032,203 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1832,005,344 - 32,040,895 (+)NCBI
Celera831,879,179 - 32,135,024 (+)NCBICelera
Cytogenetic Map8q21NCBI
Arhgap32
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541229,910,395 - 30,203,340 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541229,910,395 - 30,113,959 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP32
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29129,648,795 - 129,966,615 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111130,756,565 - 131,074,151 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011123,780,028 - 124,096,494 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111127,680,804 - 127,882,212 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11127,684,622 - 127,909,822 (-)Ensemblpanpan1.1panPan2
ARHGAP32
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.155,398,833 - 5,690,041 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl55,380,831 - 5,686,840 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha55,460,004 - 5,750,414 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.055,358,554 - 5,649,847 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl55,340,445 - 5,646,077 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.155,419,701 - 5,709,873 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.055,402,897 - 5,693,910 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.055,430,554 - 5,721,803 (+)NCBIUU_Cfam_GSD_1.0
Arhgap32
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947111,157,285 - 111,454,036 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365723,118,670 - 3,294,109 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365723,100,695 - 3,293,077 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP32
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11120,108,671 - 120,333,200 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1120,112,042 - 120,329,370 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660435,674,740 - 5,987,192 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap32
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248123,282,299 - 3,597,436 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248123,278,564 - 3,474,004 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ARHGAP32
6028 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 1
Low 10 3 3 5 2 13 2 2 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000037995   ⟹   ENSSSCP00000048405
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl955,906,954 - 56,177,418 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000039028   ⟹   ENSSSCP00000059323
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl955,906,954 - 56,045,898 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000043272   ⟹   ENSSSCP00000047643
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl955,906,959 - 56,177,551 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000050215   ⟹   ENSSSCP00000059289
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl955,906,959 - 56,088,791 (-)Ensembl
RefSeq Acc Id: XM_013979563   ⟹   XP_013835017
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1955,903,365 - 56,089,324 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979564   ⟹   XP_013835018
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1955,905,527 - 56,088,613 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063130   ⟹   XP_020918789
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1955,905,527 - 56,133,429 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063131   ⟹   XP_020918790
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1955,905,527 - 56,133,429 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063133   ⟹   XP_020918792
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1955,905,527 - 56,177,583 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063134   ⟹   XP_020918793
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1955,905,527 - 56,177,583 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063135   ⟹   XP_020918794
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1955,903,365 - 56,177,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063136   ⟹   XP_020918795
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1955,903,365 - 55,963,521 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020918794   ⟸   XM_021063135
- Peptide Label: isoform X4
- UniProtKB: A0A8D1KJ33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013835017   ⟸   XM_013979563
- Peptide Label: isoform X1
- UniProtKB: A0A8D0NJG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918795   ⟸   XM_021063136
- Peptide Label: isoform X5
- UniProtKB: A0A8D1AN92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918793   ⟸   XM_021063134
- Peptide Label: isoform X3
- UniProtKB: A0A4X1VD41 (UniProtKB/TrEMBL),   A0A287AWY4 (UniProtKB/TrEMBL),   A0A8D0RP91 (UniProtKB/TrEMBL),   A0A8D1J1G8 (UniProtKB/TrEMBL),   A0A8D1SBX8 (UniProtKB/TrEMBL),   A0A8D1W7C8 (UniProtKB/TrEMBL),   A0A8D1YRB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918792   ⟸   XM_021063133
- Peptide Label: isoform X3
- UniProtKB: A0A4X1VD41 (UniProtKB/TrEMBL),   A0A287AWY4 (UniProtKB/TrEMBL),   A0A8D0RP91 (UniProtKB/TrEMBL),   A0A8D1J1G8 (UniProtKB/TrEMBL),   A0A8D1SBX8 (UniProtKB/TrEMBL),   A0A8D1W7C8 (UniProtKB/TrEMBL),   A0A8D1YRB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918790   ⟸   XM_021063131
- Peptide Label: isoform X3
- UniProtKB: A0A4X1VD41 (UniProtKB/TrEMBL),   A0A287AWY4 (UniProtKB/TrEMBL),   A0A8D0RP91 (UniProtKB/TrEMBL),   A0A8D1J1G8 (UniProtKB/TrEMBL),   A0A8D1SBX8 (UniProtKB/TrEMBL),   A0A8D1W7C8 (UniProtKB/TrEMBL),   A0A8D1YRB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918789   ⟸   XM_021063130
- Peptide Label: isoform X3
- UniProtKB: A0A4X1VD41 (UniProtKB/TrEMBL),   A0A287AWY4 (UniProtKB/TrEMBL),   A0A8D0RP91 (UniProtKB/TrEMBL),   A0A8D1J1G8 (UniProtKB/TrEMBL),   A0A8D1SBX8 (UniProtKB/TrEMBL),   A0A8D1W7C8 (UniProtKB/TrEMBL),   A0A8D1YRB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013835018   ⟸   XM_013979564
- Peptide Label: isoform X2
- UniProtKB: A0A8D0NQH4 (UniProtKB/TrEMBL),   A0A287BT02 (UniProtKB/TrEMBL),   A0A8D0RNC2 (UniProtKB/TrEMBL),   A0A8D1IW30 (UniProtKB/TrEMBL),   A0A8D1SJ22 (UniProtKB/TrEMBL),   A0A8D1W6M9 (UniProtKB/TrEMBL),   A0A8D0HQ95 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000059323   ⟸   ENSSSCT00000039028
RefSeq Acc Id: ENSSSCP00000059289   ⟸   ENSSSCT00000050215
RefSeq Acc Id: ENSSSCP00000048405   ⟸   ENSSSCT00000037995
RefSeq Acc Id: ENSSSCP00000047643   ⟸   ENSSSCT00000043272
Protein Domains
Rho-GAP   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015238 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005000212 UniProtKB/TrEMBL
  ENSSSCG00015036229 UniProtKB/TrEMBL
  ENSSSCG00025033297 UniProtKB/TrEMBL
  ENSSSCG00035062148 UniProtKB/TrEMBL
  ENSSSCG00040064328 UniProtKB/TrEMBL
  ENSSSCG00045031683 UniProtKB/TrEMBL
  ENSSSCG00050072986 UniProtKB/TrEMBL
  ENSSSCG00055028679 UniProtKB/TrEMBL
  ENSSSCG00060059016 UniProtKB/TrEMBL
  ENSSSCG00065040386 UniProtKB/TrEMBL
  ENSSSCG00070023479 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000037995 ENTREZGENE
  ENSSSCT00000037995.3 UniProtKB/TrEMBL
  ENSSSCT00000039028.3 UniProtKB/TrEMBL
  ENSSSCT00000043272 ENTREZGENE
  ENSSSCT00000043272.3 UniProtKB/TrEMBL
  ENSSSCT00000050215 ENTREZGENE
  ENSSSCT00000050215.3 UniProtKB/TrEMBL
  ENSSSCT00005000296.1 UniProtKB/TrEMBL
  ENSSSCT00005000364.1 UniProtKB/TrEMBL
  ENSSSCT00015048335.1 UniProtKB/TrEMBL
  ENSSSCT00015049372.1 UniProtKB/TrEMBL
  ENSSSCT00015049579.1 UniProtKB/TrEMBL
  ENSSSCT00015049974.1 UniProtKB/TrEMBL
  ENSSSCT00025045744.1 UniProtKB/TrEMBL
  ENSSSCT00025045914.1 UniProtKB/TrEMBL
  ENSSSCT00035083552.1 UniProtKB/TrEMBL
  ENSSSCT00040089226.1 UniProtKB/TrEMBL
  ENSSSCT00045054629.1 UniProtKB/TrEMBL
  ENSSSCT00045054870.1 UniProtKB/TrEMBL
  ENSSSCT00050099701.1 UniProtKB/TrEMBL
  ENSSSCT00050099705.1 UniProtKB/TrEMBL
  ENSSSCT00050099707.1 UniProtKB/TrEMBL
  ENSSSCT00050099710.1 UniProtKB/TrEMBL
  ENSSSCT00055057686.1 UniProtKB/TrEMBL
  ENSSSCT00055057784.1 UniProtKB/TrEMBL
  ENSSSCT00060080623.1 UniProtKB/TrEMBL
  ENSSSCT00060080654.1 UniProtKB/TrEMBL
  ENSSSCT00065055232.1 UniProtKB/TrEMBL
  ENSSSCT00065055241.1 UniProtKB/TrEMBL
  ENSSSCT00065055245.1 UniProtKB/TrEMBL
  ENSSSCT00065055254.1 UniProtKB/TrEMBL
  ENSSSCT00070046816.1 UniProtKB/TrEMBL
  ENSSSCT00070046851.1 UniProtKB/TrEMBL
  ENSSSCT00070046887.1 UniProtKB/TrEMBL
  ENSSSCT00070046903.1 UniProtKB/TrEMBL
  ENSSSCT00070046917.1 UniProtKB/TrEMBL
  ENSSSCT00070046918.1 UniProtKB/TrEMBL
  ENSSSCT00070046931.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro PX_ARHGAP32 UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene ARHGAP32 ENTREZGENE
PANTHER CDC42 GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 32 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A287AUV8_PIG UniProtKB/TrEMBL
  A0A287AWY4 ENTREZGENE
  A0A287BS29_PIG UniProtKB/TrEMBL
  A0A287BT02 ENTREZGENE
  A0A4X1V9E9_PIG UniProtKB/TrEMBL
  A0A4X1VCZ1_PIG UniProtKB/TrEMBL
  A0A4X1VD26_PIG UniProtKB/TrEMBL
  A0A4X1VD41 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VDR6_PIG UniProtKB/TrEMBL
  A0A4X1VDW5_PIG UniProtKB/TrEMBL
  A0A8D0HQ95 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NJG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NQH4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0RNC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0RP91 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1AN92 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1IW30 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1J1G8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1KJ33 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SBX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SJ22 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1W6M9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1W7C8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1YRB2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2C7U4_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287AWY4 UniProtKB/TrEMBL
  A0A287BT02 UniProtKB/TrEMBL
  F1S6F6 UniProtKB/TrEMBL
VGNC ID VGNC:85471 ENTREZGENE