H3-3B (H3.3 histone B) - Rat Genome Database

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Gene: H3-3B (H3.3 histone B) Sus scrofa
Analyze
Symbol: H3-3B (Ensembl: H3-5)
Name: H3.3 histone B (Ensembl:histone H3.3)
RGD ID: 13931925
Description: ENCODES a protein that exhibits DNA binding (inferred); nucleosomal DNA binding (inferred); protein heterodimerization activity (inferred); INVOLVED IN cell population proliferation (ortholog); embryo implantation (ortholog); male gonad development (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); Bryant-Li-Bhoj Neurodevelopmental Syndrome 2 (ortholog); carcinoma (ortholog); FOUND IN Barr body (inferred); chromatin (inferred); chromosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: H3 histone, family 3B; H3F3B; histone H3.3; LOC100521680
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,632,365 - 5,634,726 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,632,326 - 5,634,977 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,578,702 - 5,581,109 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
H3-3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,632,365 - 5,634,726 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,632,326 - 5,634,977 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,578,702 - 5,581,109 (+)NCBISscrofa10.2Sscrofa10.2susScr3
H3-3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,776,434 - 75,779,779 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1775,776,434 - 75,785,893 (-)EnsemblGRCh38hg38GRCh38
GRCh371773,772,515 - 73,775,860 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,284,110 - 71,287,455 (-)NCBINCBI36Build 36hg18NCBI36
Build 341771,284,111 - 71,287,455NCBI
Celera1770,362,565 - 70,365,910 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,198,034 - 69,201,379 (-)NCBIHuRef
CHM1_11773,837,589 - 73,840,931 (-)NCBICHM1_1
T2T-CHM13v2.01776,669,660 - 76,678,707 (-)NCBIT2T-CHM13v2.0
H3f3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,912,787 - 115,921,313 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,912,738 - 115,918,788 (-)EnsemblGRCm39 Ensembl
GRCm3811116,021,961 - 116,026,039 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,021,912 - 116,027,962 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711115,883,275 - 115,885,818 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,837,018 - 115,840,587 (-)NCBIMGSCv36mm8
Celera11127,784,227 - 127,786,770 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.91NCBI
H3f3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,755,404 - 101,764,616 (-)NCBIGRCr8
mRatBN7.210101,256,484 - 101,258,716 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,256,480 - 101,258,709 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,317,943 - 106,320,175 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010105,781,026 - 105,783,258 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010101,177,427 - 101,179,659 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010104,573,666 - 104,575,890 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,573,664 - 104,575,890 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010103,709,482 - 103,711,706 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,130,320 - 106,132,544 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110106,144,823 - 106,147,045 (-)NCBI
Celera1099,830,619 - 99,832,836 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
H3f3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,474,727 - 6,482,244 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,475,336 - 6,478,781 (+)NCBIChiLan1.0ChiLan1.0
LOC100988671
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,821,558 - 91,824,038 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,646,832 - 96,648,754 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,728,165 - 69,730,519 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,277,614 - 75,281,106 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,277,614 - 75,281,106 (-)Ensemblpanpan1.1panPan2
LOC101963257
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,450,377 - 5,452,805 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936594958,049 - 961,708 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936594959,493 - 961,703 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103243033
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,903,252 - 45,905,605 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,902,980 - 45,904,929 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,660,280 - 16,662,641 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101698172
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248015,668,661 - 5,672,164 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in H3-3B
90 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 20 8 6 10 4 46 4 6 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000018727   ⟹   ENSSSCP00000018225
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl125,632,365 - 5,634,726 (+)Ensembl
RefSeq Acc Id: XM_003131194   ⟹   XP_003131242
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1125,632,326 - 5,634,977 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003131242   ⟸   XM_003131194
- UniProtKB: Q71LE2 (UniProtKB/Swiss-Prot),   K9IWF3 (UniProtKB/TrEMBL),   A0A8D0K7I6 (UniProtKB/TrEMBL),   A0A8D0TRT3 (UniProtKB/TrEMBL),   A0A8D0X703 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000018225   ⟸   ENSSSCT00000018727
Protein Domains
Histone H2A/H2B/H3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017202 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCG00000023971 UniProtKB/Swiss-Prot
  ENSSSCG00005011893 UniProtKB/Swiss-Prot
  ENSSSCG00005035014 UniProtKB/TrEMBL
  ENSSSCG00015036810 UniProtKB/Swiss-Prot
  ENSSSCG00015048325 UniProtKB/Swiss-Prot
  ENSSSCG00025037271 UniProtKB/Swiss-Prot
  ENSSSCG00025075957 UniProtKB/TrEMBL
  ENSSSCG00030005134 UniProtKB/Swiss-Prot
  ENSSSCG00030048865 UniProtKB/TrEMBL
  ENSSSCG00035048727 UniProtKB/Swiss-Prot
  ENSSSCG00035053743 UniProtKB/Swiss-Prot
  ENSSSCG00040044657 UniProtKB/Swiss-Prot
  ENSSSCG00040071581 UniProtKB/Swiss-Prot
  ENSSSCG00045029396 UniProtKB/Swiss-Prot
  ENSSSCG00045038628 UniProtKB/Swiss-Prot
  ENSSSCG00050017758 UniProtKB/Swiss-Prot
  ENSSSCG00050070605 UniProtKB/Swiss-Prot
  ENSSSCG00055006012 UniProtKB/Swiss-Prot
  ENSSSCG00055013826 UniProtKB/Swiss-Prot
  ENSSSCG00060029017 UniProtKB/Swiss-Prot
  ENSSSCG00060069290 UniProtKB/Swiss-Prot
  ENSSSCG00065030240 UniProtKB/Swiss-Prot
  ENSSSCG00065055858 UniProtKB/Swiss-Prot
  ENSSSCG00070007464 UniProtKB/Swiss-Prot
  ENSSSCG00070020711 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000018727 ENTREZGENE
  ENSSSCT00000018727.3 UniProtKB/Swiss-Prot
  ENSSSCT00000098149.1 UniProtKB/Swiss-Prot
  ENSSSCT00005018468.1 UniProtKB/Swiss-Prot
  ENSSSCT00005055989.1 UniProtKB/TrEMBL
  ENSSSCT00005056014.1 UniProtKB/TrEMBL
  ENSSSCT00015048919.1 UniProtKB/Swiss-Prot
  ENSSSCT00015064297.1 UniProtKB/Swiss-Prot
  ENSSSCT00025050735.1 UniProtKB/Swiss-Prot
  ENSSSCT00025104928.1 UniProtKB/TrEMBL
  ENSSSCT00030007018.1 UniProtKB/Swiss-Prot
  ENSSSCT00030068179.1 UniProtKB/TrEMBL
  ENSSSCT00035064937.1 UniProtKB/Swiss-Prot
  ENSSSCT00035071692.1 UniProtKB/Swiss-Prot
  ENSSSCT00040059852.1 UniProtKB/Swiss-Prot
  ENSSSCT00040098382.1 UniProtKB/Swiss-Prot
  ENSSSCT00045050189.1 UniProtKB/Swiss-Prot
  ENSSSCT00045067034.1 UniProtKB/Swiss-Prot
  ENSSSCT00050024132.1 UniProtKB/Swiss-Prot
  ENSSSCT00050096261.1 UniProtKB/Swiss-Prot
  ENSSSCT00055011710.1 UniProtKB/Swiss-Prot
  ENSSSCT00055027192.1 UniProtKB/Swiss-Prot
  ENSSSCT00060039203.1 UniProtKB/Swiss-Prot
  ENSSSCT00060094570.1 UniProtKB/Swiss-Prot
  ENSSSCT00065040802.1 UniProtKB/Swiss-Prot
  ENSSSCT00065076499.1 UniProtKB/Swiss-Prot
  ENSSSCT00070014391.1 UniProtKB/Swiss-Prot
  ENSSSCT00070014394.1 UniProtKB/Swiss-Prot
  ENSSSCT00070041207.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Histone-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2A/H2B/H3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H3/CENP-A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100521680 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ssc:396970 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene LOC100521680 ENTREZGENE
PANTHER HISTONE H3.3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11426 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Histone UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS HISTONEH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HISTONE_H3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HISTONE_H3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00428 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47113 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8D0K7I6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TRT3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0X703 ENTREZGENE, UniProtKB/TrEMBL
  H33_PIG UniProtKB/Swiss-Prot
  K9IWF3 ENTREZGENE, UniProtKB/TrEMBL
  Q71LE2 ENTREZGENE
VGNC ID VGNC:109832 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-13 H3-3B  H3.3 histone B  LOC100521680  histone H3.3  Symbol and/or name change 19259463 PROVISIONAL