SLC26A3 (solute carrier family 26 member 3) - Rat Genome Database

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Gene: SLC26A3 (solute carrier family 26 member 3) Sus scrofa
Analyze
Symbol: SLC26A3
Name: solute carrier family 26 member 3
RGD ID: 13931656
Description: ENCODES a protein that exhibits antiporter activity (inferred); bicarbonate transmembrane transporter activity (inferred); chloride transmembrane transporter activity (inferred); INVOLVED IN bicarbonate transport (inferred); cellular response to cAMP (inferred); chloride transmembrane transport (inferred); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; ASSOCIATED WITH Congenital Infantile Lactic Acidosis due to LAD Deficiency (ortholog); congenital secretory chloride diarrhea 1 (ortholog); diarrhea (ortholog); FOUND IN apical plasma membrane (ortholog); brush border membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: chloride anion exchanger
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9107,480,641 - 107,518,728 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19107,480,629 - 107,518,771 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29118,242,827 - 118,270,349 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:16421205   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC26A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9107,480,641 - 107,518,728 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19107,480,629 - 107,518,771 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29118,242,827 - 118,270,349 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC26A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387107,765,469 - 107,803,223 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7107,765,467 - 107,803,225 (-)EnsemblGRCh38hg38GRCh38
GRCh377107,405,914 - 107,443,668 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367107,193,153 - 107,230,873 (-)NCBINCBI36Build 36hg18NCBI36
Build 347106,999,864 - 107,037,583NCBI
Celera7102,213,002 - 102,250,772 (-)NCBICelera
Cytogenetic Map7q22.3-q31.1NCBI
HuRef7101,768,479 - 101,805,928 (-)NCBIHuRef
CHM1_17107,339,874 - 107,377,522 (-)NCBICHM1_1
T2T-CHM13v2.07109,083,905 - 109,121,574 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27106,767,027 - 106,804,797 (-)NCBI
Slc26a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391231,483,141 - 31,523,921 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1231,440,870 - 31,523,916 (+)EnsemblGRCm39 Ensembl
GRCm381231,433,142 - 31,473,922 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1231,390,871 - 31,473,917 (+)EnsemblGRCm38mm10GRCm38
MGSCv371232,123,166 - 32,158,584 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361232,024,267 - 32,059,683 (+)NCBIMGSCv36mm8
Celera1232,889,209 - 32,922,999 (+)NCBICelera
Cytogenetic Map12A2NCBI
cM Map1213.45NCBI
Slc26a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8653,751,415 - 53,792,300 (+)NCBIGRCr8
mRatBN7.2648,023,892 - 48,064,829 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl648,023,892 - 48,064,772 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx648,329,656 - 48,370,640 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0648,644,584 - 48,685,561 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0648,085,083 - 48,125,974 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0650,725,085 - 50,766,306 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl650,725,085 - 50,766,300 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0659,395,877 - 59,437,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4649,305,008 - 49,346,008 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1649,308,133 - 49,349,132 (+)NCBI
Celera647,226,207 - 47,267,145 (+)NCBICelera
Cytogenetic Map6q16NCBI
Slc26a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541012,102,356 - 12,128,620 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541012,102,356 - 12,128,620 (-)NCBIChiLan1.0ChiLan1.0
SLC26A3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26144,611,642 - 144,640,916 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17192,881,610 - 192,910,884 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0799,747,405 - 99,776,763 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17112,470,041 - 112,507,671 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7112,470,041 - 112,507,671 (-)Ensemblpanpan1.1panPan2
SLC26A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11812,817,177 - 12,843,502 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1812,808,806 - 12,843,076 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1812,453,053 - 12,487,685 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01813,080,365 - 13,114,865 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1813,080,351 - 13,114,497 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11812,897,435 - 12,931,814 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01812,817,450 - 12,852,075 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01813,045,737 - 13,080,386 (+)NCBIUU_Cfam_GSD_1.0
Slc26a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511855,218,797 - 55,253,962 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647916,350,773 - 16,377,367 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647916,350,746 - 16,374,911 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC26A3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12176,682,255 - 76,739,460 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2176,681,951 - 76,721,139 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604227,151,590 - 27,181,858 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc26a3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473921,979,172 - 22,004,716 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473921,979,164 - 22,004,794 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC26A3
1130 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High 1
Medium 7 1
Low 1 1 1 13 1
Below cutoff 1 2 3 3 1 8 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000031097   ⟹   ENSSSCP00000022695
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9107,480,641 - 107,518,728 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000067608   ⟹   ENSSSCP00000062313
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9107,484,136 - 107,518,728 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000101535   ⟹   ENSSSCP00000075089
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9107,480,641 - 107,518,728 (-)Ensembl
RefSeq Acc Id: NM_001130248   ⟹   NP_001123720
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19107,481,502 - 107,510,671 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021101946   ⟹   XP_020957605
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19107,480,629 - 107,518,771 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020957605   ⟸   XM_021101946
- Peptide Label: isoform X1
- UniProtKB: A0A8D0M7F4 (UniProtKB/TrEMBL),   A0A8W4F7A1 (UniProtKB/TrEMBL),   I3LF55 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001123720   ⟸   NM_001130248
- UniProtKB: B5A4B3 (UniProtKB/TrEMBL),   A0A4X1V0S9 (UniProtKB/TrEMBL),   A0A8D0M7F4 (UniProtKB/TrEMBL),   A0A8W4F7A1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000022695   ⟸   ENSSSCT00000031097
RefSeq Acc Id: ENSSSCP00000062313   ⟸   ENSSSCT00000067608
RefSeq Acc Id: ENSSSCP00000075089   ⟸   ENSSSCT00000101535
Protein Domains
STAS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000021813 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005045496 UniProtKB/TrEMBL
  ENSSSCG00025064112 UniProtKB/TrEMBL
  ENSSSCG00030074790 UniProtKB/TrEMBL
  ENSSSCG00035021948 UniProtKB/TrEMBL
  ENSSSCG00040074225 UniProtKB/TrEMBL
  ENSSSCG00045035204 UniProtKB/TrEMBL
  ENSSSCG00055017802 UniProtKB/TrEMBL
  ENSSSCG00060072659 UniProtKB/TrEMBL
  ENSSSCG00065023805 UniProtKB/TrEMBL
  ENSSSCG00070021656 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000031097 ENTREZGENE
  ENSSSCT00000031097.4 UniProtKB/TrEMBL
  ENSSSCT00000067608 ENTREZGENE
  ENSSSCT00000067608.2 UniProtKB/TrEMBL
  ENSSSCT00000101535.1 UniProtKB/TrEMBL
  ENSSSCT00005073574.1 UniProtKB/TrEMBL
  ENSSSCT00005073578.1 UniProtKB/TrEMBL
  ENSSSCT00025087912.1 UniProtKB/TrEMBL
  ENSSSCT00025088178.1 UniProtKB/TrEMBL
  ENSSSCT00030105054.1 UniProtKB/TrEMBL
  ENSSSCT00030105056.1 UniProtKB/TrEMBL
  ENSSSCT00035028637.1 UniProtKB/TrEMBL
  ENSSSCT00035028644.1 UniProtKB/TrEMBL
  ENSSSCT00035028649.1 UniProtKB/TrEMBL
  ENSSSCT00040102721.1 UniProtKB/TrEMBL
  ENSSSCT00040102762.1 UniProtKB/TrEMBL
  ENSSSCT00045060457.1 UniProtKB/TrEMBL
  ENSSSCT00045060614.1 UniProtKB/TrEMBL
  ENSSSCT00055034897.1 UniProtKB/TrEMBL
  ENSSSCT00055035052.1 UniProtKB/TrEMBL
  ENSSSCT00060099309.1 UniProtKB/TrEMBL
  ENSSSCT00060099348.1 UniProtKB/TrEMBL
  ENSSSCT00065031688.1 UniProtKB/TrEMBL
  ENSSSCT00065031696.1 UniProtKB/TrEMBL
  ENSSSCT00070043092.1 UniProtKB/TrEMBL
  ENSSSCT00070043104.1 UniProtKB/TrEMBL
  ENSSSCT00070043112.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.750.24 UniProtKB/TrEMBL
InterPro S04_transporter_CS UniProtKB/TrEMBL
  SLC26A/SulP_dom UniProtKB/TrEMBL
  SLC26A/SulP_fam UniProtKB/TrEMBL
  STAS_dom UniProtKB/TrEMBL
  STAS_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:100170644 UniProtKB/TrEMBL
NCBI Gene SLC26A3 ENTREZGENE
PANTHER PTHR11814 UniProtKB/TrEMBL
  PTHR11814:SF19 UniProtKB/TrEMBL
Pfam STAS UniProtKB/TrEMBL
  Sulfate_transp UniProtKB/TrEMBL
PROSITE SLC26A UniProtKB/TrEMBL
  STAS UniProtKB/TrEMBL
Superfamily-SCOP SSF52091 UniProtKB/TrEMBL
UniProt A0A4X1V0S9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V0U0_PIG UniProtKB/TrEMBL
  A0A4X1V665_PIG UniProtKB/TrEMBL
  A0A5G2QDT9_PIG UniProtKB/TrEMBL
  A0A8D0M780_PIG UniProtKB/TrEMBL
  A0A8D0M7F4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CPN1_PIG UniProtKB/TrEMBL
  A0A8W4F7A1 ENTREZGENE, UniProtKB/TrEMBL
  B5A4B3 ENTREZGENE, UniProtKB/TrEMBL
  I3LF55 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:93028 ENTREZGENE