ZNF593 (zinc finger protein 593) - Rat Genome Database

Name: ZNF593
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: ZNF593 (zinc finger protein 593) Sus scrofa

Analyze

Symbol:

ZNF593

Name:

zinc finger protein 593

RGD ID:

13930830

Description:

ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); preribosome binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (inferred); ribosome biogenesis (inferred); ASSOCIATED WITH autosomal recessive hypercholesterolemia (ortholog); Disease Progression (ortholog); genetic disease (ortholog); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNF593 (zinc finger protein 593)	HGNC	Ensembl, NCBI, OrthoDB
Mus musculus (house mouse):	Zfp593 (zinc finger protein 593)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Zfp593 (zinc finger protein 593)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Znf593 (zinc finger protein 593)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZNF593 (zinc finger protein 593)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNF593 (zinc finger protein 593)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Znf593 (zinc finger protein 593)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNF593 (zinc finger protein 593)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Znf593 (zinc finger protein 593)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	83,590,895 - 83,593,278 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	83,590,840 - 83,593,284 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive hypercholesterolemia (ISO)

Disease Progression (ISO)

genetic disease (ISO)

retinitis pigmentosa 59 (ISO)

Stomach Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of transcription by RNA polymerase II (IEA)

ribosome biogenesis (IEA)

Cellular Component

nucleolus (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

metal ion binding (IEA)

nucleic acid binding (IEA)

preribosome binding (IEA)

protein binding (ISO)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:22301074

Genomics

Comparative Map Data

ZNF593
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	83,590,895 - 83,593,278 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	83,590,840 - 83,593,284 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ZNF593
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	26,169,908 - 26,170,873 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	26,169,908 - 26,170,873 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	26,496,399 - 26,497,364 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	26,368,975 - 26,369,951 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	26,180,571 - 26,181,504	NCBI
Celera	1	24,892,757 - 24,893,733 (+)	NCBI		Celera
Cytogenetic Map	1	p36.11	NCBI
HuRef	1	24,750,428 - 24,751,404 (+)	NCBI		HuRef
CHM1_1	1	26,609,607 - 26,610,583 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	26,007,339 - 26,008,304 (+)	NCBI		T2T-CHM13v2.0

Zfp593
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	133,970,617 - 133,972,902 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	133,970,600 - 133,972,903 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	134,243,306 - 134,245,591 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	134,243,289 - 134,245,592 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	133,799,221 - 133,801,506 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	133,515,382 - 133,517,604 (-)	NCBI		MGSCv36	mm8
Celera	4	132,423,098 - 132,425,387 (-)	NCBI		Celera
Cytogenetic Map	4	D2.3	NCBI
cM Map	4	66.5	NCBI

Zfp593
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	151,746,396 - 151,748,724 (-)	NCBI		GRCr8
mRatBN7.2	5	146,462,670 - 146,464,998 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	146,462,670 - 146,465,198 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	149,164,643 - 149,166,969 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	150,934,808 - 150,937,136 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	150,920,857 - 150,923,183 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	152,462,522 - 152,464,850 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	152,462,522 - 152,464,850 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	156,221,537 - 156,223,865 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	152,987,725 - 152,990,053 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	152,998,963 - 153,000,086 (-)	NCBI
Celera	5	144,880,352 - 144,882,680 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Znf593
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	5,613,210 - 5,614,161 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	5,613,210 - 5,614,161 (+)	NCBI	ChiLan1.0	ChiLan1.0

ZNF593
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	200,700,737 - 200,701,626 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	199,798,852 - 199,799,741 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	25,430,971 - 25,431,964 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	26,497,845 - 26,498,847 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	26,497,845 - 26,498,847 (+)	Ensembl	panpan1.1		panPan2

ZNF593
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	73,819,728 - 73,820,705 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	73,819,728 - 73,820,672 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	70,396,059 - 70,397,036 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	74,382,853 - 74,383,830 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	2	71,207,242 - 71,208,225 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	72,212,974 - 72,213,951 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	73,216,891 - 73,217,868 (-)	NCBI		UU_Cfam_GSD_1.0

Znf593
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	44,866,445 - 44,867,735 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	10,691,252 - 10,694,734 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	10,691,090 - 10,692,517 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF593
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	106,596,850 - 106,597,859 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	106,596,576 - 106,597,789 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	9,820,947 - 9,822,289 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znf593
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	10,221,427 - 10,222,371 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	10,221,423 - 10,222,371 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ZNF593
30 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021095611	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK395074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01024391	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000069657 ⟹ ENSSSCP00000068256

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	83,590,895 - 83,593,278 (+)	Ensembl

RefSeq Acc Id:

XM_021095611 ⟹ XP_020951270

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	6	83,590,840 - 83,593,284 (+)	NCBI

Sequence:

show sequence

TCGCGCGAGTGACGTCATCAGAGGCGGTCCGCCGGAGCCTGCTCAGTCCCCGGCGTCACATGGC
GTCACTGCACAGTCCGGAAGTGCCCACACGTGTCCTCCCAACTCGGCTCTAGGCCCGTTGGTCC
CGCTGTTACCAGCAATGGGTCGCTCTCGCCGAACCGGCGCACACCGAGCGCACTCCCTGGCCCG
CCAGATGAAGGCGAAGCGGCGGCGGCCGGACCTCGATGAGATTCACCGCGAGCTGCGGCCCCAG
GTTGCCACAAGGACCCGACCAGACCCCGGCGCCGAGCCCGACCCCGACCTGCCAGGGGGCGGCC
TGCATCGCTGTCTGGCCTGCGCGAGATACTTCATCGATTCTGCCAACCTGAAGACCCACTTCCG
ATCCAAAGACCACAAGAAAAGGTTGAAGCAGCTGAGTGTGGAGCCCTACAGTCAGGAAGAGGCA
GAGAGGGCAGCGGGTATGGGTTCCTATGTACCTCCCCAGCGGCTGGCAGTGCCCACAGAAGTAT
CCACTGATGTCCCTGAGATGGACACATCTACTTGACAGATCCTGAGAATTCAAGGCAGAAGAGT
TGCCCATGGACAGTGATGCAAGGGCCAGTCTGGGAGAGACTGTACCAGTCTGTTTTGGCCCGGG
GTTTGGGGAGTGGATGGCCTCTTCCCAGTGCCCTCCCTCCCAATAAAATAACTGGATAAAGGGG
GCTTGCCCCTGACTCTAACCCCCAGGCCACTACTCCAAACTCATGTCCTGTAAGTTTCTCTACT
ACTCCTGTGCATGGGACCCAGGCTGCTTGGGCTTTATCCACCTTTGGTACCTGTATCCTTACCT
TCCCTCTGGGATCCTGGCATCTGAGCCGAAACCCCCCATTGGAGCCTAGGTGTGTGGGCTGGGT
AAGATCAGGTTTATAACAACCCTGCTTCTAATGAGGGCAGGGAGTGATCCCCAGAAAAGAAGTA
GGCTCCCAAGATTATAGCTGTCGCTGAGTTACATACCCCCCCAGGGCCCAGGTGGAGGCTGCCC
GCTTCATCATGGGGCCTGTGGCGGCCGTCGCTGCCCCACCATCTTCCAGACTGCATAGCAAGAG
CCGCCCAGCCCGAGGACAGCCAGCAGTGCAGCCACAATCCCAGCCAGTGGACTCCGGGGCTCTG
CCTTCAGCTCCCCGGCTATCTGCATCTGGAAATGCACAGAGGGTCCGCCTGAGGGGTCATTTGA
GACCTCTGGGAAGGTGGGGGGTGGAAAGGGGCTGAGTTAGGGGAAGGAGATATGGATGCCACTG
CTGCCCCAGGGAGATTCCACCCCAATCCCTCTCGCTTCATTGCCCATCTAGGCCCCGGCTGCTC
AGGCGGCAGGGAACGTGACAGCCTGGCTGCCGGGTGTCAACCCAGCCATGGTAGGGGGAGTAAG
GGGTCGATGGCAGAAGCCATTGGTTAAGGGTACGTACCTGTAGCACTCGAAAGTAGCCAGGGGT
CAGGCGTGGAAATCGCATGGTGGGTGCTGCTAGTGTCGCTGGTGTCCTGTGGGGCGGAAGCGGG
AATGAAGACCAGTGGCGTTTGTGGTACCAAGAAGCGGAAATCAGGGCGCAGGGTTTCCTGACCT
CTCATACGCAAGAGAGCCATGCCCTCAGAGGATGCTCACCAGTGCCTGCCTTCCCAGGTCTGGC
AGGGGGCGGAGCAGCTAGACCTTTAAATCTGTCCCTTCCCCCGCCTGCCCGCCCTGCCAGCCTT
AGGAACAGCTGTCAGGAGAGATCAGCATCAGGCCTGAGCAGCACCTCCCCCAGCCACACGGGCA
GTCCAGGCTGGGCAGGCAGGAGAGGTCTTGCCTGGGAGTATAGGGAAGTTTCAGACTGGGACCA
GGTACGGGAGGGCCTCCCCAGCCCTGGCCTTGGCCCAGTCCCTGCTTTAGTCGATTGGATGTCA
CCAATCAGCTCTCAGCAGAGGCGGGATTGGGTGCCGTATTAGTACCCCCTTCCAACTGGAGTAG
GCCTTTTTCACTTGGTTTCTCTTAATCAACCACACCTATGCTGGGGGAGGGCACATTGCACCCC
TTTCCCTTGGAGGAGTCCCTGTAGGGACTTCCCAATCTTAGCTTGGGCACAATAATAAAAGATC
TGCATCTACTGATAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020951270	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000068256
	ENSSSCP00000068256.2
	ENSSSCP00030031585.1
	ENSSSCP00045046723.1
	ENSSSCP00070043780.1

RefSeq Acc Id:	XP_020951270 ⟸ XM_021095611
- UniProtKB:	A0A4X1VQG1 (UniProtKB/TrEMBL), A0A5G2QTK2 (UniProtKB/TrEMBL), A0A8D1JF56 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGRSRRTGAHRAHSLARQMKAKRRRPDLDEIHRELRPQVATRTRPDPGAEPDPDLPGGGLHRCL ACARYFIDSANLKTHFRSKDHKKRLKQLSVEPYSQEEAERAAGMGSYVPPQRLAVPTEVSTDVP EMDTST hide sequence

RefSeq Acc Id:

ENSSSCP00000068256 ⟸ ENSSSCT00000069657

Protein Domains

C2H2-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000045776	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00030049603	UniProtKB/TrEMBL
	ENSSSCG00045038116	UniProtKB/TrEMBL
	ENSSSCG00070025877	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000069657	ENTREZGENE
	ENSSSCT00000069657.2	UniProtKB/TrEMBL
	ENSSSCT00030069167.1	UniProtKB/TrEMBL
	ENSSSCT00045065958.1	UniProtKB/TrEMBL
	ENSSSCT00070051755.1	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	Matrin/U1-like-C_Znf_C2H2	UniProtKB/TrEMBL
	Znf_C2H2_jaz	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
NCBI Gene	ZNF593	ENTREZGENE
PANTHER	ZINC FINGER PROTEIN 593	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 593	UniProtKB/TrEMBL
Pfam	zf-C2H2_jaz	UniProtKB/TrEMBL
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
SMART	ZnF_U1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/TrEMBL
UniProt	A0A4X1VQG1	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2QTK2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1JF56	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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