DYNLL2 (dynein light chain LC8-type 2) - Rat Genome Database

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Gene: DYNLL2 (dynein light chain LC8-type 2) Sus scrofa
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Symbol: DYNLL2
Name: dynein light chain LC8-type 2
RGD ID: 13930743
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein-containing complex binding (ortholog); scaffold protein binding (ortholog); INVOLVED IN apoptotic process (inferred); DNA damage response (inferred); microtubule-based process (inferred); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); intellectual disability (ortholog); Joubert syndrome 1 (ortholog); FOUND IN cytoplasmic dynein complex (ortholog); glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dynein light chain 2, cytoplasmic
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1234,349,294 - 34,356,472 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11234,348,336 - 34,356,478 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21235,383,171 - 35,390,262 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DYNLL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1234,349,294 - 34,356,472 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11234,348,336 - 34,356,478 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21235,383,171 - 35,390,262 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381758,083,419 - 58,095,542 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1758,083,419 - 58,095,542 (+)EnsemblGRCh38hg38GRCh38
GRCh371756,160,780 - 56,172,903 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361753,515,798 - 53,521,810 (+)NCBINCBI36Build 36hg18NCBI36
Build 341753,515,797 - 53,521,812NCBI
Celera1752,622,562 - 52,629,401 (+)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1751,521,612 - 51,528,449 (+)NCBIHuRef
CHM1_11756,225,816 - 56,232,655 (+)NCBICHM1_1
T2T-CHM13v2.01758,957,420 - 58,969,544 (+)NCBIT2T-CHM13v2.0
Dynll2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,870,351 - 87,892,746 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1187,870,351 - 87,878,359 (-)EnsemblGRCm39 Ensembl
GRCm381187,979,525 - 88,003,817 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,979,525 - 87,987,533 (-)EnsemblGRCm38mm10GRCm38
MGSCv371187,793,027 - 87,811,800 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361187,795,728 - 87,803,700 (-)NCBIMGSCv36mm8
Celera1197,583,461 - 97,602,228 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.35NCBI
Dynll2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81073,264,260 - 73,283,042 (-)NCBIGRCr8
mRatBN7.21072,767,035 - 72,785,824 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1072,767,035 - 72,785,805 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1077,377,490 - 77,385,515 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01076,882,434 - 76,890,459 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01072,346,936 - 72,354,961 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01075,262,536 - 75,281,302 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1075,262,537 - 75,270,561 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01074,819,177 - 74,837,880 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,263,883 - 76,271,908 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11076,278,253 - 76,286,278 (-)NCBI
Celera1071,677,302 - 71,685,328 (-)NCBICelera
Cytogenetic Map10q26NCBI
Dynll2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554514,929,186 - 4,936,027 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554514,929,186 - 4,936,027 (-)NCBIChiLan1.0ChiLan1.0
DYNLL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21974,257,528 - 74,265,364 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11779,068,504 - 79,076,340 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01752,161,701 - 52,169,538 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11757,021,357 - 57,025,750 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1757,021,357 - 57,025,750 (+)Ensemblpanpan1.1panPan2
DYNLL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1932,748,229 - 32,768,896 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl932,762,278 - 32,767,103 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha931,986,475 - 32,007,301 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0933,555,947 - 33,576,771 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl933,570,149 - 33,574,978 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1932,340,575 - 32,361,395 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0932,623,924 - 32,644,951 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0932,707,694 - 32,728,760 (+)NCBIUU_Cfam_GSD_1.0
Dynll2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560232,097,388 - 32,106,244 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364904,968,806 - 4,977,727 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364904,968,806 - 4,977,691 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11635,310,154 - 35,317,964 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1635,312,088 - 35,318,018 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660776,127,027 - 6,134,841 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dynll2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479512,932,460 - 12,940,498 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479512,932,425 - 12,940,503 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DYNLL2
199 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000027876   ⟹   ENSSSCP00000020319
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1234,349,294 - 34,356,472 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000088839   ⟹   ENSSSCP00000070437
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1234,352,014 - 34,356,472 (+)Ensembl
RefSeq Acc Id: XM_003131635   ⟹   XP_003131683
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11234,349,289 - 34,356,478 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021067271   ⟹   XP_020922930
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11234,348,336 - 34,356,478 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020922930   ⟸   XM_021067271
- UniProtKB: A0A4X1SJK3 (UniProtKB/TrEMBL),   F2Z536 (UniProtKB/TrEMBL),   Q8WNY6 (UniProtKB/TrEMBL),   A0A8D1B0S1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003131683   ⟸   XM_003131635
- UniProtKB: F2Z536 (UniProtKB/TrEMBL),   A0A4X1SJK3 (UniProtKB/TrEMBL),   Q8WNY6 (UniProtKB/TrEMBL),   A0A8D1B0S1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000070437   ⟸   ENSSSCT00000088839
Ensembl Acc Id: ENSSSCP00000020319   ⟸   ENSSSCT00000027876


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000020962 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015063652 UniProtKB/TrEMBL
  ENSSSCG00025018984 UniProtKB/TrEMBL
  ENSSSCG00030051673 UniProtKB/TrEMBL
  ENSSSCG00035066175 UniProtKB/TrEMBL
  ENSSSCG00040015501 UniProtKB/TrEMBL
  ENSSSCG00045020904 UniProtKB/TrEMBL
  ENSSSCG00050035023 UniProtKB/TrEMBL
  ENSSSCG00055017793 UniProtKB/TrEMBL
  ENSSSCG00060020239 UniProtKB/TrEMBL
  ENSSSCG00065027453 UniProtKB/TrEMBL
  ENSSSCG00065027591 UniProtKB/TrEMBL
  ENSSSCG00070001643 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000027876 ENTREZGENE
  ENSSSCT00000027876.2 UniProtKB/TrEMBL
  ENSSSCT00000088839.2 UniProtKB/TrEMBL
  ENSSSCT00015085244.1 UniProtKB/TrEMBL
  ENSSSCT00025025756.1 UniProtKB/TrEMBL
  ENSSSCT00030071991.1 UniProtKB/TrEMBL
  ENSSSCT00035089130.1 UniProtKB/TrEMBL
  ENSSSCT00040020873.1 UniProtKB/TrEMBL
  ENSSSCT00045035663.1 UniProtKB/TrEMBL
  ENSSSCT00050047079.1 UniProtKB/TrEMBL
  ENSSSCT00055034885.1 UniProtKB/TrEMBL
  ENSSSCT00060027367.1 UniProtKB/TrEMBL
  ENSSSCT00065036986.1 UniProtKB/TrEMBL
  ENSSSCT00065036994.1 UniProtKB/TrEMBL
  ENSSSCT00065037164.1 UniProtKB/TrEMBL
  ENSSSCT00070003064.1 UniProtKB/TrEMBL
  ENSSSCT00070003072.1 UniProtKB/TrEMBL
  ENSSSCT00070003074.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.740.10 UniProtKB/TrEMBL
InterPro DLC_sf UniProtKB/TrEMBL
  Dynein_light_1/2_CS UniProtKB/TrEMBL
  Dynein_light_chain_typ-1/2 UniProtKB/TrEMBL
KEGG Report ssc:100512860 UniProtKB/TrEMBL
NCBI Gene DYNLL2 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN 1, CYTOPLASMIC UniProtKB/TrEMBL
  DYNEIN LIGHT CHAIN 2, CYTOPLASMIC UniProtKB/TrEMBL
  PTHR11886 UniProtKB/TrEMBL
Pfam Dynein_light UniProtKB/TrEMBL
PROSITE DYNEIN_LIGHT_1 UniProtKB/TrEMBL
SMART Dynein_light UniProtKB/TrEMBL
Superfamily-SCOP SSF54648 UniProtKB/TrEMBL
UniProt A0A4X1SJK3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SKB8_PIG UniProtKB/TrEMBL
  A0A5G2R8I6_PIG UniProtKB/TrEMBL
  A0A8D1B0S1 ENTREZGENE, UniProtKB/TrEMBL
  F2Z536 ENTREZGENE
  Q8WNY6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F2Z536 UniProtKB/TrEMBL
VGNC ID VGNC:87501 ENTREZGENE