PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2) - Rat Genome Database

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Gene: PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2) Sus scrofa
Analyze
Symbol: PPP1R2
Name: protein phosphatase 1 regulatory inhibitor subunit 2
RGD ID: 13923387
Description: ENCODES a protein that exhibits molecular function inhibitor activity (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of protein binding (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN dendritic spine (ortholog); growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein phosphatase inhibitor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113132,460,186 - 132,489,490 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213142,032,745 - 142,060,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PPP1R2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113132,460,186 - 132,489,490 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213142,032,745 - 142,060,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383195,514,428 - 195,543,325 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3195,514,428 - 195,543,386 (-)EnsemblGRCh38hg38GRCh38
GRCh373195,241,224 - 195,270,148 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363196,722,513 - 196,751,362 (-)NCBINCBI36Build 36hg18NCBI36
Celera3193,649,379 - 193,678,278 (-)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3192,611,567 - 192,640,691 (-)NCBIHuRef
CHM1_13195,204,104 - 195,233,114 (-)NCBICHM1_1
T2T-CHM13v2.03198,221,391 - 198,250,329 (-)NCBIT2T-CHM13v2.0
Ppp1r2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391631,070,359 - 31,094,095 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1631,070,355 - 31,094,095 (-)EnsemblGRCm39 Ensembl
GRCm381631,251,541 - 31,275,277 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1631,251,537 - 31,275,277 (-)EnsemblGRCm38mm10GRCm38
MGSCv371631,251,627 - 31,275,363 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361631,171,288 - 31,195,024 (-)NCBIMGSCv36mm8
Celera1631,759,323 - 31,783,001 (-)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1621.41NCBI
Ppp1r2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81182,977,634 - 82,999,426 (+)NCBIGRCr8
mRatBN7.21169,472,676 - 69,494,468 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1169,472,555 - 69,494,463 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1178,309,669 - 78,331,462 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01170,962,762 - 70,986,263 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01169,998,758 - 70,020,550 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01172,748,789 - 73,034,683 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1173,022,063 - 73,034,682 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01175,823,211 - 75,823,466 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01176,095,398 - 76,108,035 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41171,319,294 - 71,342,716 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11171,376,882 - 71,400,305 (+)NCBI
Celera1168,892,093 - 68,913,866 (+)NCBICelera
Cytogenetic Map11q22NCBI
Ppp1r2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542013,592,508 - 13,613,165 (+)NCBIChiLan1.0ChiLan1.0
PPP1R2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22193,426,366 - 193,453,449 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13193,431,086 - 193,460,360 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03192,797,787 - 192,826,706 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13203,097,226 - 203,126,167 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3203,097,226 - 203,126,167 (-)Ensemblpanpan1.1panPan2
PPP1R2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13330,525,906 - 30,555,415 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3330,525,906 - 30,555,415 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3330,551,942 - 30,581,442 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03330,778,041 - 30,807,809 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3330,778,031 - 30,807,794 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13330,572,596 - 30,602,272 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03330,609,224 - 30,638,729 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03331,230,994 - 31,261,224 (+)NCBIUU_Cfam_GSD_1.0
Ppp1r2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602143,699,565 - 143,712,480 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936833225,330 - 238,222 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11589,559,149 - 89,585,767 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1589,555,566 - 89,586,548 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604163,321,183 - 63,349,993 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473062,576,490 - 62,603,993 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PPP1R2
491 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_021070085   ⟹   XP_020925744
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113132,460,186 - 132,489,490 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020925744   ⟸   XM_021070085
- UniProtKB: A0A287AX77 (UniProtKB/TrEMBL),   A0A4X1U4L8 (UniProtKB/TrEMBL),   A0A0B8RZ91 (UniProtKB/TrEMBL),   A0A8D0SAE7 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000039249 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015022725 UniProtKB/TrEMBL
  ENSSSCG00025048568 UniProtKB/TrEMBL
  ENSSSCG00030044362 UniProtKB/TrEMBL
  ENSSSCG00035044233 UniProtKB/TrEMBL
  ENSSSCG00040041358 UniProtKB/TrEMBL
  ENSSSCG00045000253 UniProtKB/TrEMBL
  ENSSSCG00050054135 UniProtKB/TrEMBL
  ENSSSCG00055012701 UniProtKB/TrEMBL
  ENSSSCG00060043447 UniProtKB/TrEMBL
  ENSSSCG00065004643 UniProtKB/TrEMBL
  ENSSSCG00070013965 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000052618 ENTREZGENE
  ENSSSCT00000052618.3 UniProtKB/TrEMBL
  ENSSSCT00000072012.2 UniProtKB/TrEMBL
  ENSSSCT00000074283.2 UniProtKB/TrEMBL
  ENSSSCT00000094323.1 UniProtKB/TrEMBL
  ENSSSCT00015030268.1 UniProtKB/TrEMBL
  ENSSSCT00025066219.1 UniProtKB/TrEMBL
  ENSSSCT00030061891.1 UniProtKB/TrEMBL
  ENSSSCT00035058773.1 UniProtKB/TrEMBL
  ENSSSCT00040055459.1 UniProtKB/TrEMBL
  ENSSSCT00045000347.1 UniProtKB/TrEMBL
  ENSSSCT00050073812.1 UniProtKB/TrEMBL
  ENSSSCT00055025120.1 UniProtKB/TrEMBL
  ENSSSCT00060058934.1 UniProtKB/TrEMBL
  ENSSSCT00065006376.1 UniProtKB/TrEMBL
  ENSSSCT00070027331.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.250.1050 UniProtKB/TrEMBL
InterPro PPI-2 UniProtKB/TrEMBL
NCBI Gene PPP1R2 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE INHIBITOR 2-RELATED UniProtKB/TrEMBL
  PTHR12398 UniProtKB/TrEMBL
Pfam IPP-2 UniProtKB/TrEMBL
UniProt A0A0B8RZ91 ENTREZGENE
  A0A287AX77 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U4L8 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2Q9D0_PIG UniProtKB/TrEMBL
  A0A5G2RDG4_PIG UniProtKB/TrEMBL
  A0A8D0SAE7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FMH2_PIG UniProtKB/TrEMBL