IFI44 (interferon induced protein 44)

Gene: IFI44 (interferon induced protein 44) Sus scrofa

Analyze

Symbol:

IFI44

Name:

interferon induced protein 44

RGD ID:

13916886

Description:

INVOLVED IN response to bacterium (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); Human Influenza (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

interferon-induced protein 44; interferon-inducible microtubular aggregate protein 44; MATP44

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	134,633,615 - 134,650,203 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	134,634,679 - 134,649,857 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	124,790,060 - 124,806,704 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

genetic disease (ISO)

Human Influenza (ISO)

multisystem inflammatory syndrome in children (ISO)

Spontaneous Abortions (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

immune response (IBA,IEA)

response to bacterium (IEA,ISO)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:14681463

Genomics

Comparative Map Data

IFI44
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	134,633,615 - 134,650,203 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	134,634,679 - 134,649,857 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	124,790,060 - 124,806,704 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IFI44
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	78,649,789 - 78,664,078 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	78,649,796 - 78,664,078 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	79,115,474 - 79,129,763 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	78,888,104 - 78,902,345 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	78,827,536 - 78,841,778	NCBI
Celera	1	77,354,992 - 77,369,278 (+)	NCBI		Celera
Cytogenetic Map	1	p31.1	NCBI
HuRef	1	77,247,062 - 77,261,348 (+)	NCBI		HuRef
CHM1_1	1	79,231,865 - 79,246,152 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	78,488,644 - 78,502,933 (+)	NCBI		T2T-CHM13v2.0

Ifi44
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	151,436,559 - 151,455,580 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	151,436,559 - 151,455,597 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	151,730,922 - 151,749,910 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	151,730,922 - 151,749,960 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	151,393,886 - 151,412,923 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	151,668,310 - 151,687,235 (-)	NCBI		MGSCv36	mm8
Celera	3	158,189,999 - 158,212,999 (-)	NCBI		Celera
Cytogenetic Map	3	H3	NCBI
cM Map	3	76.91	NCBI

Ifi44
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	243,286,050 - 243,303,869 (-)	NCBI		GRCr8
mRatBN7.2	2	240,626,058 - 240,643,879 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	240,626,066 - 240,643,844 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	248,425,005 - 248,442,792 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	246,312,027 - 246,329,814 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	241,179,510 - 241,197,300 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	256,897,765 - 256,915,591 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	256,897,772 - 256,915,569 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	275,575,813 - 275,593,615 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	250,039,104 - 250,056,890 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	250,053,708 - 250,081,761 (-)	NCBI
Celera	2	232,564,862 - 232,582,621 (-)	NCBI		Celera
Cytogenetic Map	2	q45	NCBI

IFI44
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	148,230,776 - 148,246,855 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	147,387,213 - 147,401,682 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	77,863,283 - 77,877,626 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	79,943,774 - 79,958,083 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	79,943,774 - 79,958,083 (+)	Ensembl	panpan1.1		panPan2

IFI44
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	68,361,724 - 68,377,991 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	68,364,494 - 68,377,876 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	71,020,189 - 71,036,460 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	68,947,142 - 68,963,402 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	6	68,454,006 - 68,470,248 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	68,399,198 - 68,415,470 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	68,883,819 - 68,900,068 (-)	NCBI		UU_Cfam_GSD_1.0

Ifi44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	89,870,875 - 89,885,122 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936571	5,381,254 - 5,395,470 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936571	5,381,312 - 5,395,455 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IFI44
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	54,539,512 - 54,554,787 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	54,539,392 - 54,554,785 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	62,977,917 - 62,998,438 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in IFI44
236 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	8	2	1	5		1		3	1
Low	2	2	2		2	22	2		2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001246205	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK233687	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK391273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU633953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01081518	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HQ266637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000004165 ⟹ ENSSSCP00000004071

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	134,633,615 - 134,650,203 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000048806 ⟹ ENSSSCP00000036739

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	134,633,615 - 134,649,857 (-)	Ensembl

RefSeq Acc Id:

NM_001246205 ⟹ NP_001233134

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	6	134,634,679 - 134,649,857 (-)	NCBI

Sequence:

show sequence

ATGGCAGTGACAACTTGCTTGACCTGGATGCAGGAAAAGCATCTGAAAACTTATTTTGGAGAAG
AGCAGTTTAGCCTTCTCTATAAGGCCAGTGTCCATGGATTCTCTAAAGAGAAGTTGCTTGACAG
ATGCTCTCATCAAGGATCTATTCTAACAGTGATTTATAATGAATATCACATTCTTGGTGCCTAT
ATGCCAGGGGGTTACCTGGGAGAATTGGACATTTCCATCACCCTTTTTGCCTTTCAAGAGACTG
AAATTTCGAAGTGCGAAATAGGACCGCTTAATCCATGTTTGTTGTTTAGTGGAAATAATATCAA
TTCTCAATTCATTATAAATCTAGAGAAAAAAGCGGTGGTTACTAGCGTGACTACAATGGAAAAG
CTTGGACTACCTCAGTGTTGTATGTCCTTTAAGGAATGTGAAGTTTTTCGATGTGAAGATTTAT
TGGACAAAAGGAGTGTGGATGGGATTATTGAGCTCAAGGAGAGCTTAATGTCTACCATAAGAAC
TTACAAACCATATGGAGGCCTGGTTCACCAAATACAAATTCTGCTTCTGGGTCCAATTGGAGCT
GGGAAGTCCAGCTTTTTCAACGCAGTGAAGTCTGTCTTCCGAGGCCATGTCACGAACCAGGCTT
TGGTGGGTTCTGATATAACTGGCGTATCTGAAAAATACAGAAGATATGTCGTTAAGGATGGGAA
GGATGGCGACCCCCTGCCATTTATTCTGTGTGATTTACCAGGGCTGAGTGAGAAAGAAGGCAGA
CTGTGCCTGGATGACATACTCTCCGTCTTAAAAGGCCATGTTGCTGACAGATACCAGTTTAATT
CCATGAATCCAGTCAAACCAGGTCATGGTGACTATATATGCTACCCATTGCTGAAGGACAGAAT
CCATTGTGTGGCCTTTGTGTTCAGTGCCTACTCTGTTCACTGCCTCTCTGATGAGATGGTGGAA
AAGATCAAAAGAATTCGAAAGGAGTTGATTAAGTGTGGCATGGTACAGGTGGTATTGCTCACTC
ACGTGGACACCTTGGATCTGATTACAAAAGGTGACCTAATAGACATATACAAATGTGTGCCTGT
GAAACTCAAGCTAGAGGAACTTCACAGAGAATTTGGATTTCCTCTTTCTGACATCTTTGTGGTT
AGTAATTATTCCTCAGAGTGGGAGCTGGAGCCTGTCAAGGACGTTCTGATCCTCTCTGCACTGA
GACAGATGCTGTGGGCTGCAGATGACTTCTTAGAGGACTTGCCTCTTGAGGAGACAAATAGAGG
TGTTTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001233134	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AEE02032	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000004071
	ENSSSCP00000004071.3
	ENSSSCP00000036739.2
	ENSSSCP00040013350.1
	ENSSSCP00070032223.1

RefSeq Acc Id:

NP_001233134 ⟸ NM_001246205

- UniProtKB:

F4ZS17 (UniProtKB/TrEMBL), A0A8D1DWI4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAVTTCLTWMQEKHLKTYFGEEQFSLLYKASVHGFSKEKLLDRCSHQGSILTVIYNEYHILGAY
MPGGYLGELDISITLFAFQETEISKCEIGPLNPCLLFSGNNINSQFIINLEKKAVVTSVTTMEK
LGLPQCCMSFKECEVFRCEDLLDKRSVDGIIELKESLMSTIRTYKPYGGLVHQIQILLLGPIGA
GKSSFFNAVKSVFRGHVTNQALVGSDITGVSEKYRRYVVKDGKDGDPLPFILCDLPGLSEKEGR
LCLDDILSVLKGHVADRYQFNSMNPVKPGHGDYICYPLLKDRIHCVAFVFSAYSVHCLSDEMVE
KIKRIRKELIKCGMVQVVLLTHVDTLDLITKGDLIDIYKCVPVKLKLEELHREFGFPLSDIFVV
SNYSSEWELEPVKDVLILSALRQMLWAADDFLEDLPLEETNRGV

hide sequence

RefSeq Acc Id:

ENSSSCP00000036739 ⟸ ENSSSCT00000048806

RefSeq Acc Id:

ENSSSCP00000004071 ⟸ ENSSSCT00000004165

Protein Domains

TLDc

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000003763	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00040024047	UniProtKB/TrEMBL
	ENSSSCG00070019449	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000004165	ENTREZGENE
	ENSSSCT00000004165.5	UniProtKB/TrEMBL
	ENSSSCT00000048806.3	UniProtKB/TrEMBL
	ENSSSCT00040032216.1	UniProtKB/TrEMBL
	ENSSSCT00070038495.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	TLDc_dom	UniProtKB/TrEMBL
KEGG Report	ssc:100525523	UniProtKB/TrEMBL
NCBI Gene	IFI44	ENTREZGENE
PANTHER	INTERFERON-INDUCED PROTEIN 44	UniProtKB/TrEMBL
	PTHR14241:SF3	UniProtKB/TrEMBL
PROSITE	TLDC	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A286ZYN3_PIG	UniProtKB/TrEMBL
	A0A4X1US14_PIG	UniProtKB/TrEMBL
	A0A8D1DWI4	ENTREZGENE, UniProtKB/TrEMBL
	F1S9T2_PIG	UniProtKB/TrEMBL
	F4ZS17	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:97102	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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