GDF9 (growth differentiation factor 9) - Rat Genome Database

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Gene: GDF9 (growth differentiation factor 9) Sus scrofa
Analyze
Symbol: GDF9
Name: growth differentiation factor 9
RGD ID: 13916690
Description: ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN blastocyst development; embryonic cleavage; ovarian cumulus expansion; ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm; INTERACTS WITH zearalenone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: growth/differentiation factor 9
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2135,180,104 - 135,186,389 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12135,181,494 - 135,184,451 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,650,007 - 140,652,964 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
zearalenone  (EXP)

References
Additional References at PubMed
PMID:14681463   PMID:15147411   PMID:15189836   PMID:16538032   PMID:17222994   PMID:18355759   PMID:19359354   PMID:24313324  


Genomics

Comparative Map Data
GDF9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2135,180,104 - 135,186,389 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12135,181,494 - 135,184,451 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,650,007 - 140,652,964 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GDF9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5132,861,181 - 132,866,884 (-)EnsemblGRCh38hg38GRCh38
GRCh385132,861,181 - 132,866,651 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375132,196,877 - 132,202,576 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,224,777 - 132,228,376 (-)NCBINCBI36hg18NCBI36
Build 345132,225,179 - 132,228,124NCBI
Celera5128,326,902 - 128,330,501 (-)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5127,389,594 - 127,393,194 (-)NCBIHuRef
CHM1_15131,630,163 - 131,633,762 (-)NCBICHM1_1
Gdf9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,321,773 - 53,328,731 (+)NCBIGRCm39mm39
GRCm39 Ensembl1153,321,850 - 53,328,731 (+)Ensembl
GRCm381153,430,774 - 53,437,904 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,431,023 - 53,437,904 (+)EnsemblGRCm38mm10GRCm38
MGSCv371153,246,788 - 53,251,405 (+)NCBIGRCm37mm9NCBIm37
MGSCv361153,276,801 - 53,281,323 (+)NCBImm8
Celera1158,013,006 - 58,017,623 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.94NCBI
Gdf9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21037,589,200 - 37,599,970 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1037,595,679 - 37,599,672 (+)Ensembl
Rnor_6.01038,782,519 - 38,793,238 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,788,992 - 38,792,940 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,564,774 - 38,574,967 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41038,899,125 - 38,903,073 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11038,905,554 - 38,909,503 (+)NCBI
Celera1036,942,737 - 36,946,686 (+)NCBICelera
Cytogenetic Map10q22NCBI
Gdf9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554084,234,208 - 4,239,795 (-)NCBIChiLan1.0ChiLan1.0
GDF9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15134,437,497 - 134,442,706 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,437,497 - 134,442,846 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05128,278,496 - 128,284,003 (-)NCBIMhudiblu_PPA_v0panPan3
GDF9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11121,143,982 - 21,148,945 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1121,143,975 - 21,149,825 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,947,216 - 19,950,085 (-)NCBI
ROS_Cfam_1.01121,931,257 - 21,936,235 (-)NCBI
UMICH_Zoey_3.11120,650,008 - 20,652,875 (-)NCBI
UNSW_CanFamBas_1.01120,497,735 - 20,500,586 (-)NCBI
UU_Cfam_GSD_1.01121,140,232 - 21,143,105 (-)NCBI
Gdf9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,347,586 - 115,353,836 (+)NCBI
SpeTri2.0NW_0049366472,351,604 - 2,357,043 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GDF9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,678,956 - 35,684,378 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2335,679,368 - 35,682,338 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603442,258,633 - 42,263,520 (+)NCBIVero_WHO_p1.0
Gdf9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473339,235,128 - 39,240,557 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1
Low 10 4 3 5 1 22 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000015611   ⟹   ENSSSCP00000015199
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2135,180,104 - 135,186,389 (-)Ensembl
RefSeq Acc Id: NM_001001909   ⟹   NP_001001909
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12135,181,494 - 135,184,451 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001001909   ⟸   NM_001001909
- Peptide Label: precursor
- UniProtKB: Q6GUA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000015199   ⟸   ENSSSCT00000015611
Protein Domains
TGF_BETA_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014288 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070020175 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000015199 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070033532 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015611 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070040026 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  Growth_differentiation_fac-9 UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
KEGG Report ssc:414285 UniProtKB/TrEMBL
NCBI Gene GDF9 ENTREZGENE
PANTHER PTHR11848 UniProtKB/TrEMBL
  PTHR11848:SF19 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A4X1UVS7_PIG UniProtKB/TrEMBL
  G9BWP8_PIG UniProtKB/TrEMBL
  Q6DQX1_PIG UniProtKB/TrEMBL
  Q6GUA6 ENTREZGENE, UniProtKB/TrEMBL
  Q6KCM2_PIG UniProtKB/TrEMBL
  Q6KCM3_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88404 ENTREZGENE