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Gene: MSTN (myostatin) Sus scrofa

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Symbol:

MSTN

Name:

myostatin

RGD ID:

13916436

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to dexamethasone stimulus (ortholog); cellular response to hypoxia (ortholog); myoblast migration involved in skeletal muscle regeneration (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Burns (ortholog); Cachexia (ortholog); FOUND IN extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

GDF-8; GDF8; GDF8:MSTN; growth differentiation factor 8; growth/differentiation factor 8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MSTN (myostatin)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Mstn (myostatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Mstn (myostatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mstn (myostatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MSTN (myostatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MSTN (myostatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mstn (myostatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MSTN (myostatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mstn (myostatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	94,620,270 - 94,628,545 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	94,623,526 - 94,628,440 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	105,734,309 - 105,739,223 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amyotrophic lateral sclerosis (ISO)

Burns (ISO)

Cachexia (ISO)

congestive heart failure (ISO)

hypothyroidism (ISO)

immunodeficiency 31B (ISO)

muscular atrophy (ISO)

myocardial infarction (ISO)

Myocardial Reperfusion Injury (ISO)

Neurodevelopmental Disorders (ISO)

peripheral vascular disease (ISO)

uremia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to dexamethasone stimulus (IEA,ISO)

cellular response to hypoxia (ISO)

muscle cell cellular homeostasis (IEA)

myoblast migration involved in skeletal muscle regeneration (IEA,ISS)

negative regulation of insulin receptor signaling pathway (IEA)

negative regulation of kinase activity (ISO)

negative regulation of muscle hypertrophy (ISO)

negative regulation of myoblast differentiation (IEA)

negative regulation of myoblast proliferation (ISS)

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA)

negative regulation of satellite cell differentiation (ISS)

negative regulation of skeletal muscle satellite cell proliferation (ISS)

negative regulation of skeletal muscle tissue growth (IEA,ISO)

ovulation cycle process (ISO)

positive regulation of DNA-templated transcription (IEA)

positive regulation of lamellipodium assembly (IEA,ISS)

positive regulation of macrophage chemotaxis (IEA,ISS)

response to electrical stimulus (ISO)

response to estrogen (ISO)

response to ethanol (ISO)

response to glucocorticoid (ISO)

response to gravity (ISO)

response to muscle activity (ISO)

response to testosterone (ISO)

signal transduction (IEA)

skeletal muscle atrophy (ISO)

skeletal muscle satellite cell differentiation (IEA)

skeletal muscle tissue regeneration (IEA,ISO)

transforming growth factor beta receptor signaling pathway (IEA,ISO)

Cellular Component

extracellular region (IEA)

extracellular space (IBA,IEA,ISO)

membrane (IEA)

Molecular Function

cytokine activity (IBA,IEA)

growth factor activity (IEA)

heparin binding (IEA)

identical protein binding (IEA,ISS)

protein binding (ISO)

protein homodimerization activity (IEA)

signaling receptor binding (IEA)

References

Additional References at PubMed

PMID:9356471	PMID:9682443	PMID:10612246	PMID:15986890	PMID:16248430	PMID:16366271	PMID:17573916	PMID:18822098	PMID:19674865	PMID:20497155	PMID:21571901	PMID:22160830
PMID:22301074	PMID:22342668	PMID:23134308	PMID:24628723	PMID:25007254	PMID:25377122	PMID:26066356	PMID:26488621	PMID:26564781	PMID:27530319	PMID:30032202	PMID:30645618
PMID:30699111	PMID:30921567	PMID:31104696	PMID:32078127	PMID:33097765

Genomics

Comparative Map Data

MSTN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	94,620,270 - 94,628,545 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	94,623,526 - 94,628,440 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	105,734,309 - 105,739,223 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MSTN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	190,055,700 - 190,062,729 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	190,055,700 - 190,062,729 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	190,920,426 - 190,927,455 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	190,628,671 - 190,635,700 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	190,745,932 - 190,752,961	NCBI
Celera	2	184,515,357 - 184,522,386 (-)	NCBI		Celera
Cytogenetic Map	2	q32.2	NCBI
HuRef	2	182,780,433 - 182,787,462 (-)	NCBI		HuRef
CHM1_1	2	190,926,378 - 190,933,407 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	190,545,060 - 190,552,089 (-)	NCBI		T2T-CHM13v2.0

Mstn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	53,100,799 - 53,107,238 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	53,100,799 - 53,107,238 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	53,061,640 - 53,068,079 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	53,061,640 - 53,068,079 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	53,118,507 - 53,124,923 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	53,006,208 - 53,012,624 (+)	NCBI		MGSCv36	mm8
Celera	1	53,601,512 - 53,607,928 (+)	NCBI		Celera
Cytogenetic Map	1	C1.1	NCBI
cM Map	1	26.99	NCBI

Mstn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	55,944,513 - 55,950,913 (-)	NCBI		GRCr8
mRatBN7.2	9	48,452,533 - 48,458,933 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	48,452,533 - 48,458,933 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	56,995,653 - 57,000,498 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	62,118,483 - 62,123,328 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	60,414,473 - 60,419,318 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	53,310,977 - 53,315,804 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	53,309,598 - 53,315,915 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	52,977,371 - 52,982,198 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	45,426,831 - 45,431,658 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	45,428,244 - 45,433,072 (-)	NCBI
Celera	9	46,124,738 - 46,129,565 (-)	NCBI		Celera
Cytogenetic Map	9	q22	NCBI

Mstn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	8,914,482 - 8,923,465 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	8,914,505 - 8,921,190 (+)	NCBI	ChiLan1.0	ChiLan1.0

MSTN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	92,751,094 - 92,761,026 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	92,765,891 - 92,773,149 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	77,364,927 - 77,452,426 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	195,283,903 - 195,290,922 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	195,283,903 - 195,290,922 (-)	Ensembl	panpan1.1		panPan2

MSTN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	729,172 - 734,255 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	729,172 - 734,362 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	1,685,007 - 1,690,090 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	623,197 - 628,235 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	621,860 - 628,368 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	633,617 - 638,697 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	601,655 - 606,733 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	629,871 - 634,951 (-)	NCBI		UU_Cfam_GSD_1.0

Mstn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	148,842,726 - 148,849,304 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936506	7,988,718 - 7,996,971 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936506	7,988,879 - 7,996,260 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MSTN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	75,564,816 - 75,570,956 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	75,565,152 - 75,570,528 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	123,900,932 - 123,908,109 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mstn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624854	5,892,938 - 5,899,473 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624854	5,893,051 - 5,899,380 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in MSTN
41 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system
5	2	21	3	1	9	8	21	3	5

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_214435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF019623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF033855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF093798	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF188635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF188636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF188637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF188638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AH010972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ133580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ237662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ237920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY162179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY208121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY448008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY527152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY527153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU928361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EF490986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EF490987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EF490988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EF490989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EF490990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EF612791	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GU182312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GU182313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HM241657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HQ180174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JN630464	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000017472 ⟹ ENSSSCP00000017001

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	94,620,270 - 94,628,545 (-)	Ensembl

RefSeq Acc Id:

NM_214435 ⟹ NP_999600

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	15	94,623,526 - 94,628,440 (-)	NCBI

Sequence:

show sequence

ATGCAAAAACTGCAAATCTATGTTTATATTTACCTGTTTATGCTGATTGTTGCTGGTCCCGTGG
ATCTGAATGAGAACAGCGAGCAAAAGGAAAATGTGGAAAAAGAGGGGCTGTGTAATGCATGTAT
GTGGAGACAAAACACTAAATCTTCAAGACTAGAAGCCATAAAAATTCAAATCCTCAGTAAACTT
CGCCTGGAAACAGCTCCTAACATTAGCAAAGATGCTATAAGACAACTTTTGCCCAAAGCTCCTC
CACTCCGGGAACTGATTGATCAGTACGATGTCCAGAGAGATGACAGCAGTGATGGCTCCTTGGA
AGATGATGATTATCACGCTACGACGGAAACGATCATTACCATGCCTACAGAGTCTGATCTTCTA
ATGCAAGTGGAAGGAAAACCCAAATGCTGCTTCTTTAAATTTAGCTCTAAAATACAATACAATA
AAGTAGTAAAGGCCCAACTGTGGATATATCTGAGACCCGTCAAGACTCCTACAACAGTGTTTGT
GCAAATCCTGAGACTCATCAAACCCATGAAAGACGGTACAAGGTATACTGGAATCCGATCTCTG
AAACTTGACATGAACCCAGGCACTGGTATTTGGCAGAGCATTGATGTGAAGACAGTGTTGCAAA
ATTGGCTCAAACAACCTGAATCCAACTTAGGCATTGAAATCAAAGCTTTAGATGAGAATGGTCA
TGATCTTGCTGTAACCTTCCCAGGACCAGGAGAAGATGGGCTGAATCCCTTTTTAGAAGTCAAG
GTAACAGACACACCAAAAAGATCCAGGAGAGATTTTGGACTCGACTGTGATGAGCACTCAACAG
AATCTCGATGCTGTCGTTACCCTCTAACTGTGGATTTTGAAGCTTTTGGATGGGACTGGATTAT
TGCACCCAAAAGATATAAGGCCAGTTACTGCTCTGGAGAGTGTGAATTTGTATTTTTACAAAAA
TACCCTCACACTCATCTTGTGCACCAAGCAAACCCCAGAGGTTCAGCAGGCCCCTGCTGTACTC
CCACAAAGATGTCTCCAATCAATATGCTATATTTTAATGGCAAAGAACAAATAATATATGGGAA
AATTCCAGCCATGGTAGTAGATCGCTGTGGGTGCTCATGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_999600	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB86690	(Get FASTA)	NCBI Sequence Viewer
	AAC08035	(Get FASTA)	NCBI Sequence Viewer
	AAC62489	(Get FASTA)	NCBI Sequence Viewer
	AAF02770	(Get FASTA)	NCBI Sequence Viewer
	AAF02771	(Get FASTA)	NCBI Sequence Viewer
	AAF02772	(Get FASTA)	NCBI Sequence Viewer
	AAF02773	(Get FASTA)	NCBI Sequence Viewer
	AAK83853	(Get FASTA)	NCBI Sequence Viewer
	AAO23664	(Get FASTA)	NCBI Sequence Viewer
	AAO31983	(Get FASTA)	NCBI Sequence Viewer
	AAR18245	(Get FASTA)	NCBI Sequence Viewer
	AAS18674	(Get FASTA)	NCBI Sequence Viewer
	AAS18675	(Get FASTA)	NCBI Sequence Viewer
	ABO64638	(Get FASTA)	NCBI Sequence Viewer
	ABO64639	(Get FASTA)	NCBI Sequence Viewer
	ABO64640	(Get FASTA)	NCBI Sequence Viewer
	ABO64641	(Get FASTA)	NCBI Sequence Viewer
	ABO64642	(Get FASTA)	NCBI Sequence Viewer
	ABR08657	(Get FASTA)	NCBI Sequence Viewer
	ACZ68334	(Get FASTA)	NCBI Sequence Viewer
	ACZ68335	(Get FASTA)	NCBI Sequence Viewer
	ADQ74915	(Get FASTA)	NCBI Sequence Viewer
	ADV78519	(Get FASTA)	NCBI Sequence Viewer
	AEP13978	(Get FASTA)	NCBI Sequence Viewer
	CAB39561	(Get FASTA)	NCBI Sequence Viewer
	CAB40109	(Get FASTA)	NCBI Sequence Viewer
	CAB40844	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000017001
	ENSSSCP00000017001.2
	ENSSSCP00015000900.1
	ENSSSCP00025029196.1
	ENSSSCP00030010461.1
	ENSSSCP00035014874.1
	ENSSSCP00040010829.1
	ENSSSCP00045012947.1
	ENSSSCP00050006740.1
	ENSSSCP00055034200.1
	ENSSSCP00060040929.1
	ENSSSCP00065014182.1
	ENSSSCP00070015094.1
GenBank Protein	O18831	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_999600 ⟸ NM_214435
- Peptide Label:	precursor
- UniProtKB:	Q6SVB3 (UniProtKB/TrEMBL), A5Z1X3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQKLQIYVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACMWRQNTKSSRLEAIKIQILSKL RLETAPNISKDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDLL MQVEGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVKTPTTVFVQILRLIKPMKDGTRYTGIRSL KLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVK VTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKASYCSGECEFVFLQK YPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS hide sequence

Ensembl Acc Id:

ENSSSCP00000017001 ⟸ ENSSSCT00000017472

Protein Domains

TGF-beta family profile TGF-beta propeptide

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000016047	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSSSCG00015002286	UniProtKB/Swiss-Prot
	ENSSSCG00025049835	UniProtKB/Swiss-Prot
	ENSSSCG00030016859	UniProtKB/Swiss-Prot
	ENSSSCG00035028194	UniProtKB/Swiss-Prot
	ENSSSCG00040018971	UniProtKB/Swiss-Prot
	ENSSSCG00045011070	UniProtKB/Swiss-Prot
	ENSSSCG00050012141	UniProtKB/Swiss-Prot
	ENSSSCG00055021878	UniProtKB/Swiss-Prot
	ENSSSCG00060069269	UniProtKB/Swiss-Prot
	ENSSSCG00065025598	UniProtKB/Swiss-Prot
	ENSSSCG00070009359	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSSSCT00000017472	ENTREZGENE
	ENSSSCT00000017472.5	UniProtKB/Swiss-Prot
	ENSSSCT00015002832.1	UniProtKB/Swiss-Prot
	ENSSSCT00025067980.1	UniProtKB/Swiss-Prot
	ENSSSCT00030023330.1	UniProtKB/Swiss-Prot
	ENSSSCT00035037306.1	UniProtKB/Swiss-Prot
	ENSSSCT00040025633.1	UniProtKB/Swiss-Prot
	ENSSSCT00045018814.1	UniProtKB/Swiss-Prot
	ENSSSCT00050016408.1	UniProtKB/Swiss-Prot
	ENSSSCT00055042989.1	UniProtKB/Swiss-Prot
	ENSSSCT00060094644.1	UniProtKB/Swiss-Prot
	ENSSSCT00065034252.1	UniProtKB/Swiss-Prot
	ENSSSCT00070018169.1	UniProtKB/Swiss-Prot
Gene3D-CATH	2.10.90.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.60.120.970	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Cystine-knot_cytokine	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TGF-b_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TGF-b_propeptide	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TGF-beta-rel	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TGFb_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	ssc:399534	UniProtKB/TrEMBL
NCBI Gene	MSTN	ENTREZGENE
PANTHER	PTHR11848	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR11848:SF150	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	TGF_beta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TGFb_propeptide	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	TGF_BETA_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TGF_BETA_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	TGFB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF57501	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A5Z1X3	ENTREZGENE, UniProtKB/TrEMBL
	E9KYT4_PIG	UniProtKB/TrEMBL
	E9M2L9_PIG	UniProtKB/TrEMBL
	GDF8_PIG	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6SVB3	ENTREZGENE, UniProtKB/TrEMBL
	Q866T6_PIG	UniProtKB/TrEMBL
	Q9TSY2_PIG	UniProtKB/TrEMBL
	Q9TSY4_PIG	UniProtKB/TrEMBL
UniProt Secondary	Q540D6	UniProtKB/Swiss-Prot
VGNC ID	VGNC:96320	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM