ELANE (elastase, neutrophil expressed) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ELANE (elastase, neutrophil expressed) Sus scrofa
Analyze
Symbol: ELANE
Name: elastase, neutrophil expressed
RGD ID: 13912620
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); heparin binding (ortholog); peptidase activity (ortholog); INVOLVED IN acute inflammatory response to antigenic stimulus (ortholog); defense response to bacterium (ortholog); defense response to fungus (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); anthrax disease (ortholog); cerebral creatine deficiency syndrome (ortholog); FOUND IN extracellular space (ortholog); secretory granule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: neutrophil elastase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,509,344 - 77,516,027 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,513,769 - 77,516,118 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,480,250 - 77,485,906 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
ELANE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,509,344 - 77,516,027 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,513,769 - 77,516,118 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,480,250 - 77,485,906 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELANE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl19851,014 - 856,247 (+)EnsemblGRCh38hg38GRCh38
GRCh3819850,997 - 856,250 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3719852,303 - 856,243 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619803,291 - 807,246 (+)NCBINCBI36hg18NCBI36
Build 3419803,290 - 807,244NCBI
Celera19777,442 - 781,374 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef19621,154 - 625,109 (+)NCBIHuRef
CHM1_119851,610 - 855,840 (+)NCBICHM1_1
Elane
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,722,146 - 79,724,050 (+)NCBIGRCm39mm39
GRCm39 Ensembl1079,722,081 - 79,724,049 (+)Ensembl
GRCm381079,886,312 - 79,888,216 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,886,247 - 79,888,215 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,349,057 - 79,350,961 (+)NCBIGRCm37mm9NCBIm37
MGSCv361079,289,464 - 79,291,246 (+)NCBImm8
Celera1080,901,123 - 80,903,026 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Elane
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.279,817,251 - 9,819,174 (-)NCBI
Rnor_6.0 Ensembl712,638,322 - 12,640,232 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0712,638,320 - 12,640,168 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0712,808,042 - 12,809,890 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,329,642 - 11,331,490 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1711,329,643 - 11,331,467 (-)NCBI
Celera77,992,002 - 7,993,850 (-)NCBICelera
Cytogenetic Map7q11NCBI
ELANE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.119820,455 - 828,181 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v019276,499 - 280,598 (-)NCBIMhudiblu_PPA_v0panPan3
ELANE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,789,044 - 57,790,932 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,788,062 - 57,790,932 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,591,060 - 57,592,948 (-)NCBI
ROS_Cfam_1.02058,531,328 - 58,533,216 (-)NCBI
UMICH_Zoey_3.12057,586,105 - 57,588,011 (-)NCBI
UNSW_CanFamBas_1.02058,065,758 - 58,067,646 (-)NCBI
UU_Cfam_GSD_1.02058,268,788 - 58,270,676 (-)NCBI
ELANE
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16599,392 - 604,925 (+)NCBI
ChlSab1.1 Ensembl6601,217 - 604,725 (+)Ensembl
Vero_WHO_p1.0NW_0236660818,311,933 - 8,315,809 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 5 1 3 4 1 6 1 1 1
Below cutoff 3 2 1 9 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000027015   ⟹   ENSSSCP00000024494
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl277,509,344 - 77,516,024 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000038011   ⟹   ENSSSCP00000032976
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl277,513,773 - 77,516,027 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000048227   ⟹   ENSSSCP00000036167
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl277,513,444 - 77,516,024 (-)Ensembl
RefSeq Acc Id: XM_003122986   ⟹   XP_003123034
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1277,513,769 - 77,516,118 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003123034 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003123034   ⟸   XM_003122986
- Sequence:
RefSeq Acc Id: ENSSSCP00000024494   ⟸   ENSSSCT00000027015
RefSeq Acc Id: ENSSSCP00000032976   ⟸   ENSSSCT00000038011
RefSeq Acc Id: ENSSSCP00000036167   ⟸   ENSSSCT00000048227
Protein Domains
Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000029130 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070026798 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000024494 UniProtKB/TrEMBL
  ENSSSCP00000032976 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000036167 UniProtKB/TrEMBL
  ENSSSCP00070045568 UniProtKB/TrEMBL
  ENSSSCP00070045570 UniProtKB/TrEMBL
  ENSSSCP00070045571 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000027015 UniProtKB/TrEMBL
  ENSSSCT00000038011 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000048227 UniProtKB/TrEMBL
  ENSSSCT00070053749 UniProtKB/TrEMBL
  ENSSSCT00070053750 UniProtKB/TrEMBL
  ENSSSCT00070053751 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene ELANE ENTREZGENE
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A286ZN14_PIG UniProtKB/TrEMBL
  A0A286ZXH8_PIG UniProtKB/TrEMBL
  A0A4X1VPT2_PIG UniProtKB/TrEMBL
  A0A4X1VUN2_PIG UniProtKB/TrEMBL
  A0A4X1VWC4_PIG UniProtKB/TrEMBL
  I3LK80_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87637 ENTREZGENE