TADA2B (transcriptional adaptor 2B) - Rat Genome Database

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Pathways
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Gene: TADA2B (transcriptional adaptor 2B) Sus scrofa
Analyze
Symbol: TADA2B
Name: transcriptional adaptor 2B
RGD ID: 13904575
Description: ENCODES a protein that exhibits chromatin binding (inferred); metal ion binding (inferred); transcription coactivator activity (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred); SAGA complex (inferred); SAGA-type complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcriptional adapter 2-beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl83,812,257 - 3,828,108 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.183,815,056 - 3,828,113 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.283,382,879 - 3,395,926 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)
SAGA complex  (IEA)
SAGA-type complex  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TADA2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl83,812,257 - 3,828,108 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.183,815,056 - 3,828,113 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.283,382,879 - 3,395,926 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TADA2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3847,043,372 - 7,057,952 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl47,041,899 - 7,057,952 (+)EnsemblGRCh38hg38GRCh38
GRCh3747,045,099 - 7,059,679 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3647,096,057 - 7,110,580 (+)NCBINCBI36Build 36hg18NCBI36
Celera46,948,574 - 6,963,098 (+)NCBICelera
Cytogenetic Map4p16.1NCBI
HuRef46,972,544 - 6,986,943 (+)NCBIHuRef
CHM1_147,043,661 - 7,058,063 (+)NCBICHM1_1
T2T-CHM13v2.047,015,207 - 7,029,792 (+)NCBIT2T-CHM13v2.0
Tada2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39536,631,014 - 36,641,629 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl536,631,014 - 36,641,629 (-)EnsemblGRCm39 Ensembl
GRCm38536,473,670 - 36,484,285 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl536,473,670 - 36,484,285 (-)EnsemblGRCm38mm10GRCm38
MGSCv37536,816,319 - 36,826,934 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36536,788,898 - 36,801,389 (-)NCBIMGSCv36mm8
Celera533,954,645 - 33,965,272 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map519.14NCBI
Tada2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81478,503,939 - 78,523,715 (+)NCBIGRCr8
mRatBN7.21474,279,286 - 74,290,758 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1474,279,217 - 74,290,755 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1478,721,498 - 78,732,797 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01479,962,371 - 79,973,670 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01476,407,344 - 76,418,643 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01479,446,057 - 79,457,341 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1479,446,057 - 79,457,333 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01479,085,067 - 79,096,343 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41479,860,285 - 79,871,569 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1473,217,684 - 73,228,968 (+)NCBICelera
Cytogenetic Map14q21NCBI
Tada2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555143,468,087 - 3,478,085 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555143,468,078 - 3,478,085 (-)NCBIChiLan1.0ChiLan1.0
TADA2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v237,309,691 - 7,324,272 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan147,238,736 - 7,253,316 (+)NCBINHGRI_mPanPan1
PanPan1.147,110,732 - 7,125,109 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl47,110,732 - 7,125,100 (+)Ensemblpanpan1.1panPan2
TADA2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1359,108,678 - 59,122,112 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl359,106,351 - 59,122,125 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha361,754,793 - 61,768,975 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0359,579,546 - 59,593,955 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl359,579,573 - 59,593,943 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1359,076,843 - 59,091,023 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0359,278,756 - 59,291,865 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0359,633,068 - 59,647,258 (+)NCBIUU_Cfam_GSD_1.0
Tada2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528565,166,165 - 65,178,335 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647718,876,132 - 18,878,760 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TADA2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12743,157,292 - 43,170,970 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2743,157,389 - 43,168,664 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604790,012,223 - 90,026,523 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tada2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475523,262,687 - 23,272,522 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475523,262,693 - 23,272,531 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TADA2B
434 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1
Low 10 3 3 4 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000038401   ⟹   ENSSSCP00000032908
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl83,812,257 - 3,828,108 (-)Ensembl
RefSeq Acc Id: XM_003356846   ⟹   XP_003356894
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.183,815,056 - 3,828,113 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003356894   ⟸   XM_003356846
- UniProtKB: A0A4X1SMK5 (UniProtKB/TrEMBL),   I3LTB2 (UniProtKB/TrEMBL),   A0A8D1M1R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000032908   ⟸   ENSSSCT00000038401
Protein Domains
Myb-like   SANT   ZZ-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000029624 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00030071686 UniProtKB/TrEMBL
  ENSSSCG00035003822 UniProtKB/TrEMBL
  ENSSSCG00040006271 UniProtKB/TrEMBL
  ENSSSCG00045029230 UniProtKB/TrEMBL
  ENSSSCG00050030851 UniProtKB/TrEMBL
  ENSSSCG00055002389 UniProtKB/TrEMBL
  ENSSSCG00060041905 UniProtKB/TrEMBL
  ENSSSCG00065069448 UniProtKB/TrEMBL
  ENSSSCG00070002363 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000038401 ENTREZGENE
  ENSSSCT00000038401.3 UniProtKB/TrEMBL
  ENSSSCT00030100360.1 UniProtKB/TrEMBL
  ENSSSCT00035004753.1 UniProtKB/TrEMBL
  ENSSSCT00040008254.1 UniProtKB/TrEMBL
  ENSSSCT00045049884.1 UniProtKB/TrEMBL
  ENSSSCT00050041481.1 UniProtKB/TrEMBL
  ENSSSCT00055004531.1 UniProtKB/TrEMBL
  ENSSSCT00060056821.1 UniProtKB/TrEMBL
  ENSSSCT00065095355.1 UniProtKB/TrEMBL
  ENSSSCT00070004597.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  3.30.60.90 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro ADA2-like_ZZ UniProtKB/TrEMBL
  Ada2/TADA2 UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  SANT_dom UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  Znf_ZZ UniProtKB/TrEMBL
  Znf_ZZ_sf UniProtKB/TrEMBL
NCBI Gene TADA2B ENTREZGENE
PANTHER TRANSCRIPTIONAL ADAPTER 2-BETA UniProtKB/TrEMBL
  TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED UniProtKB/TrEMBL
Pfam Myb_DNA-binding UniProtKB/TrEMBL
PIRSF Transcriptional_adaptor_2 UniProtKB/TrEMBL
PROSITE MYB_LIKE UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
  ZF_ZZ_1 UniProtKB/TrEMBL
  ZF_ZZ_2 UniProtKB/TrEMBL
SMART SANT UniProtKB/TrEMBL
  ZnF_ZZ UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF46689 UniProtKB/TrEMBL
UniProt A0A4X1SMK5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1M1R2 ENTREZGENE, UniProtKB/TrEMBL
  I3LTB2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:93707 ENTREZGENE