JAM2 (junctional adhesion molecule 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: JAM2 (junctional adhesion molecule 2) Sus scrofa
Analyze
Symbol: JAM2
Name: junctional adhesion molecule 2
RGD ID: 13898354
Description: ENCODES a protein that exhibits integrin binding (inferred); INVOLVED IN negative regulation of cell adhesion (ortholog); negative regulation of myelination (ortholog); spermatid development (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); Alzheimer's disease (ortholog); Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy (ortholog); FOUND IN axon (ortholog); somatodendritic compartment (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: junctional adhesion molecule B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13189,165,975 - 189,275,839 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113189,199,789 - 189,275,843 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213199,074,626 - 199,167,813 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:30032202  


Genomics

Comparative Map Data
JAM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13189,165,975 - 189,275,839 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113189,199,789 - 189,275,843 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213199,074,626 - 199,167,813 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JAM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382125,639,258 - 25,717,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2125,639,258 - 25,717,562 (+)EnsemblGRCh38hg38GRCh38
GRCh372127,011,570 - 27,089,874 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362125,933,460 - 26,009,106 (+)NCBINCBI36Build 36hg18NCBI36
Build 342125,933,459 - 26,009,106NCBI
Celera2112,195,003 - 12,270,650 (+)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2112,414,742 - 12,493,008 (+)NCBIHuRef
CHM1_12126,572,234 - 26,650,529 (+)NCBICHM1_1
T2T-CHM13v2.02123,996,799 - 24,075,106 (+)NCBIT2T-CHM13v2.0
Jam2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391684,571,011 - 84,623,268 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1684,571,011 - 84,622,816 (+)EnsemblGRCm39 Ensembl
GRCm381684,774,123 - 84,826,380 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1684,774,123 - 84,825,928 (+)EnsemblGRCm38mm10GRCm38
MGSCv371684,774,368 - 84,823,129 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361684,657,025 - 84,707,359 (+)NCBIMGSCv36mm8
Celera1684,978,233 - 85,028,276 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1646.92NCBI
Jam2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81137,316,287 - 37,366,517 (+)NCBIGRCr8
mRatBN7.21123,830,820 - 23,880,071 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1123,831,106 - 23,880,063 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1132,537,340 - 32,586,308 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01125,237,747 - 25,286,715 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01124,426,449 - 24,475,421 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01124,235,310 - 24,285,279 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,266,345 - 24,285,275 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01127,864,652 - 27,913,275 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41124,310,704 - 24,315,219 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1123,670,522 - 23,719,259 (+)NCBICelera
Cytogenetic Map11q11NCBI
Jam2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540725,571,570 - 25,599,551 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540725,531,891 - 25,599,551 (+)NCBIChiLan1.0ChiLan1.0
JAM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22221,832,762 - 21,912,523 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12116,690,714 - 16,769,718 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02112,084,083 - 12,162,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12125,442,054 - 25,518,987 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2125,441,765 - 25,519,304 (+)Ensemblpanpan1.1panPan2
JAM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13121,137,378 - 21,198,278 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3121,137,363 - 21,197,668 (+)NCBICanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3121,194,569 - 21,197,958 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03121,191,218 - 21,252,072 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3121,191,320 - 21,253,587 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13121,209,766 - 21,270,172 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03121,210,940 - 21,271,401 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03121,686,386 - 21,746,819 (+)NCBIUU_Cfam_GSD_1.0
Jam2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497121,697,079 - 21,751,432 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366401,929,255 - 1,984,872 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366401,930,450 - 1,984,438 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JAM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1266,557,271 - 66,635,937 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl266,559,820 - 66,635,339 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605086,918,147 - 86,997,127 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jam2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474513,704,652 - 13,776,172 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474513,704,031 - 13,778,749 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in JAM2
3922 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 3 22
Low 8 4 5 2 1 2 3 1
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000024945   ⟹   ENSSSCP00000021713
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13189,199,978 - 189,275,839 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000029574   ⟹   ENSSSCP00000026494
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13189,165,975 - 189,275,447 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000036930   ⟹   ENSSSCP00000031449
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13189,166,039 - 189,275,837 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000059102   ⟹   ENSSSCP00000057834
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13189,239,197 - 189,275,837 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000074077   ⟹   ENSSSCP00000060708
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13189,239,979 - 189,265,174 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000075916   ⟹   ENSSSCP00000068168
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13189,199,978 - 189,275,839 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000081205   ⟹   ENSSSCP00000062881
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13189,239,564 - 189,275,838 (+)Ensembl
RefSeq Acc Id: XM_021070861   ⟹   XP_020926520
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113189,199,789 - 189,275,843 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002338017
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113189,199,789 - 189,275,843 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002338018
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113189,199,789 - 189,275,843 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020926520   ⟸   XM_021070861
- UniProtKB: A0A8D1XSC6 (UniProtKB/TrEMBL),   I3LCD8 (UniProtKB/TrEMBL),   A0A4X1UFP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000026494   ⟸   ENSSSCT00000029574
RefSeq Acc Id: ENSSSCP00000060708   ⟸   ENSSSCT00000074077
RefSeq Acc Id: ENSSSCP00000021713   ⟸   ENSSSCT00000024945
RefSeq Acc Id: ENSSSCP00000068168   ⟸   ENSSSCT00000075916
RefSeq Acc Id: ENSSSCP00000057834   ⟸   ENSSSCT00000059102
RefSeq Acc Id: ENSSSCP00000031449   ⟸   ENSSSCT00000036930
RefSeq Acc Id: ENSSSCP00000062881   ⟸   ENSSSCT00000081205
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000023028 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025066711 UniProtKB/TrEMBL
  ENSSSCG00030021165 UniProtKB/TrEMBL
  ENSSSCG00035046648 UniProtKB/TrEMBL
  ENSSSCG00040070009 UniProtKB/TrEMBL
  ENSSSCG00050075164 UniProtKB/TrEMBL
  ENSSSCG00055009690 UniProtKB/TrEMBL
  ENSSSCG00060044234 UniProtKB/TrEMBL
  ENSSSCG00065017003 UniProtKB/TrEMBL
  ENSSSCG00070016376 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000024945 ENTREZGENE
  ENSSSCT00000024945.3 UniProtKB/TrEMBL
  ENSSSCT00000029574.4 UniProtKB/TrEMBL
  ENSSSCT00000036930.3 UniProtKB/TrEMBL
  ENSSSCT00000059102 ENTREZGENE
  ENSSSCT00000059102.3 UniProtKB/TrEMBL
  ENSSSCT00000074077.2 UniProtKB/TrEMBL
  ENSSSCT00000075916.1 UniProtKB/TrEMBL
  ENSSSCT00025091670.1 UniProtKB/TrEMBL
  ENSSSCT00030029376.1 UniProtKB/TrEMBL
  ENSSSCT00035062061.1 UniProtKB/TrEMBL
  ENSSSCT00040096450.1 UniProtKB/TrEMBL
  ENSSSCT00050102999.1 UniProtKB/TrEMBL
  ENSSSCT00055019203.1 UniProtKB/TrEMBL
  ENSSSCT00060059994.1 UniProtKB/TrEMBL
  ENSSSCT00065022582.1 UniProtKB/TrEMBL
  ENSSSCT00065022588.1 UniProtKB/TrEMBL
  ENSSSCT00070032301.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  JAM2 UniProtKB/TrEMBL
NCBI Gene JAM2 ENTREZGENE
PANTHER JUNCTIONAL ADHESION MOLECULE B UniProtKB/TrEMBL
  PTHR44663 UniProtKB/TrEMBL
Pfam Ig_3 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A286ZIP6_PIG UniProtKB/TrEMBL
  A0A287BNT2_PIG UniProtKB/TrEMBL
  A0A4X1UFP2 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2Q9R8_PIG UniProtKB/TrEMBL
  A0A5G2QTK5_PIG UniProtKB/TrEMBL
  A0A8D1XSC6 ENTREZGENE, UniProtKB/TrEMBL
  I3LCD8 ENTREZGENE, UniProtKB/TrEMBL
  I3LQW2_PIG UniProtKB/TrEMBL
UniProt Secondary A0A5G2QXF5 UniProtKB/TrEMBL
VGNC ID VGNC:89276 ENTREZGENE