MROH6 (maestro heat like repeat family member 6) - Rat Genome Database

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Gene: MROH6 (maestro heat like repeat family member 6) Sus scrofa
Analyze
Symbol: MROH6
Name: maestro heat like repeat family member 6
RGD ID: 13893031
Description: ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 2 (ortholog); epidermolysis bullosa simplex with muscular dystrophy (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: maestro heat-like repeat-containing protein family member 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4988,185 - 993,815 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14988,367 - 994,613 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.241,047,340 - 1,052,340 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MROH6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4988,185 - 993,815 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14988,367 - 994,613 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.241,047,340 - 1,052,340 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MROH6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388143,566,192 - 143,572,772 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8143,566,192 - 143,572,772 (-)EnsemblGRCh38hg38GRCh38
GRCh378144,648,362 - 144,654,942 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,719,505 - 144,726,071 (-)NCBINCBI36Build 36hg18NCBI36
Celera8140,958,618 - 140,965,169 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8139,899,739 - 139,906,458 (-)NCBIHuRef
CHM1_18144,688,572 - 144,695,162 (-)NCBICHM1_1
T2T-CHM13v2.08144,715,587 - 144,723,834 (-)NCBIT2T-CHM13v2.0
Mroh6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,753,085 - 75,762,544 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1575,755,986 - 75,760,619 (-)EnsemblGRCm39 Ensembl
GRCm381575,881,867 - 75,890,693 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1575,884,137 - 75,888,770 (-)EnsemblGRCm38mm10GRCm38
MGSCv371575,714,567 - 75,719,153 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1577,383,915 - 77,389,704 (-)NCBICelera
Cytogenetic Map15D3NCBI
Mroh6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,448,738 - 109,456,034 (-)NCBIGRCr8
mRatBN7.27107,566,212 - 107,576,469 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7107,569,554 - 107,574,173 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.07116,914,826 - 116,921,487 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,915,888 - 116,920,507 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,806,795 - 116,812,693 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,858,182 - 113,862,801 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7103,925,489 - 103,932,151 (-)NCBICelera
Cytogenetic Map7q34NCBI
Mroh6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,274,074 - 2,278,756 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,273,127 - 2,279,674 (-)NCBIChiLan1.0ChiLan1.0
MROH6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,049,281 - 161,058,053 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18136,568,014 - 136,575,834 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08140,319,049 - 140,327,986 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18143,335,453 - 143,341,221 (-)NCBIpanpan1.1PanPan1.1panPan2
MROH6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,229,270 - 37,234,677 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,229,886 - 37,234,609 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,185,628 - 37,191,172 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,700,965 - 37,706,510 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,701,796 - 37,706,525 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,375,302 - 37,380,845 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,492,259 - 37,497,798 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01337,973,432 - 37,978,983 (-)NCBIUU_Cfam_GSD_1.0
Mroh6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,133,001 - 1,138,350 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364708,559,368 - 8,564,425 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MROH6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,786,500 - 137,793,567 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8137,787,542 - 137,792,830 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660392,098,869 - 2,107,377 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mroh6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473513,177,934 - 13,184,226 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473513,176,828 - 13,185,174 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MROH6
105 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium
Low 1 1 1
Below cutoff 2 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000007613   ⟹   ENSSSCP00000007410
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4988,185 - 993,815 (+)Ensembl
RefSeq Acc Id: XM_021090446   ⟹   XP_020946105
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14988,367 - 994,613 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021090448   ⟹   XP_020946107
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14988,367 - 994,613 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020946105 (Get FASTA)   NCBI Sequence Viewer  
  XP_020946107 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000007410
  ENSSSCP00000007410.5
  ENSSSCP00025048595.1
Reference Protein Sequences
RefSeq Acc Id: XP_020946105   ⟸   XM_021090446
- Peptide Label: isoform X1
- UniProtKB: A0A8D0TNK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020946107   ⟸   XM_021090448
- Peptide Label: isoform X2
- UniProtKB: F1SEW4 (UniProtKB/TrEMBL),   A0A8D0TNK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000007410   ⟸   ENSSSCT00000007613


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006948 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025077427 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007613 ENTREZGENE
  ENSSSCT00000007613.5 UniProtKB/TrEMBL
  ENSSSCT00025107665.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Maestro_heat-like_prot UniProtKB/TrEMBL
  Maestro_HEAT_rpt UniProtKB/TrEMBL
NCBI Gene MROH6 ENTREZGENE
PANTHER MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 6 UniProtKB/TrEMBL
  PTHR23120 UniProtKB/TrEMBL
Pfam Maestro_HEAT UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8D0TNK3 ENTREZGENE, UniProtKB/TrEMBL
  F1SEW4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:90347 ENTREZGENE