TMEM106B (transmembrane protein 106B) - Rat Genome Database
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Gene: TMEM106B (transmembrane protein 106B) Sus scrofa
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Symbol: TMEM106B
Name: transmembrane protein 106B
RGD ID: 13891389
Description: ENCODES a protein that exhibits ATPase binding (ortholog); INVOLVED IN lysosomal lumen acidification (ortholog); lysosomal protein catabolic process (ortholog); lysosomal transport (ortholog); ASSOCIATED WITH Frontotemporal Lobar Degeneration (ortholog); Hypomyelinating Leukodystrophy 16 (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN lysosomal membrane (ortholog); lysosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl981,837,688 - 81,864,193 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1981,837,654 - 81,864,215 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2990,000,953 - 90,023,858 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
TMEM106B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl981,837,688 - 81,864,193 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1981,837,654 - 81,864,215 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2990,000,953 - 90,023,858 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM106B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl712,211,270 - 12,243,367 (+)EnsemblGRCh38hg38GRCh38
GRCh38712,211,294 - 12,243,367 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37712,250,920 - 12,282,993 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36712,217,451 - 12,243,411 (+)NCBINCBI36hg18NCBI36
Celera712,228,868 - 12,254,926 (+)NCBI
Cytogenetic Map7p21.3NCBI
HuRef712,126,997 - 12,153,058 (+)NCBIHuRef
CHM1_1712,251,533 - 12,277,588 (+)NCBICHM1_1
CRA_TCAGchr7v2712,304,117 - 12,330,178 (+)NCBI
Tmem106b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39613,069,758 - 13,089,268 (+)NCBIGRCm39mm39
GRCm39 Ensembl613,069,758 - 13,089,268 (+)Ensembl
GRCm38613,069,759 - 13,089,269 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl613,069,759 - 13,089,269 (+)EnsemblGRCm38mm10GRCm38
MGSCv37613,019,759 - 13,039,269 (+)NCBIGRCm37mm9NCBIm37
MGSCv36613,019,856 - 13,035,064 (+)NCBImm8
Celera613,170,992 - 13,190,653 (+)NCBICelera
Cytogenetic Map6A1NCBI
Tmem106b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2441,328,125 - 41,347,315 (+)NCBI
Rnor_6.0 Ensembl439,517,548 - 39,535,169 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0439,517,679 - 39,534,491 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0439,352,537 - 39,371,725 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4438,398,245 - 38,415,059 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1438,516,785 - 38,533,599 (-)NCBI
Celera436,699,886 - 36,716,700 (+)NCBICelera
Cytogenetic Map4q21NCBI
Tmem106b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543218,619,413 - 18,639,151 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543218,619,418 - 18,644,876 (+)NCBIChiLan1.0ChiLan1.0
TMEM106B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1712,249,919 - 12,275,969 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl712,250,010 - 12,270,693 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0712,905,192 - 12,931,170 (+)NCBIMhudiblu_PPA_v0panPan3
TMEM106B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1427,140,687 - 27,161,333 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11427,140,692 - 27,166,652 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tmem106b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367611,663,099 - 1,689,580 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM106B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12145,899,428 - 45,921,500 (-)NCBI
ChlSab1.1 Ensembl2145,900,531 - 45,920,569 (-)Ensembl
Tmem106b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248277,015,267 - 7,043,853 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000046979   ⟹   ENSSSCP00000051024
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl981,837,688 - 81,864,193 (+)Ensembl
RefSeq Acc Id: XM_003130176   ⟹   XP_003130224
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1981,837,654 - 81,864,215 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021102434   ⟹   XP_020958093
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1981,837,897 - 81,864,215 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003130224 (Get FASTA)   NCBI Sequence Viewer  
  XP_020958093 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003130224   ⟸   XM_003130176
- UniProtKB: A0A287B4J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020958093   ⟸   XM_021102434
- Sequence:
RefSeq Acc Id: ENSSSCP00000051024   ⟸   ENSSSCT00000046979


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032740 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070010318 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000051024 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070016698 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000046979 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070020083 UniProtKB/TrEMBL
InterPro DUF1356_TMEM106 UniProtKB/TrEMBL
KEGG Report ssc:100512621 UniProtKB/TrEMBL
NCBI Gene TMEM106B ENTREZGENE
PANTHER PTHR28556 UniProtKB/TrEMBL
Pfam DUF1356 UniProtKB/TrEMBL
UniProt A0A287B4J0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TN99_PIG UniProtKB/TrEMBL
VGNC ID VGNC:104075 ENTREZGENE