SLC16A8 (solute carrier family 16 member 8) - Rat Genome Database

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Gene: SLC16A8 (solute carrier family 16 member 8) Sus scrofa
Analyze
Symbol: SLC16A8
Name: solute carrier family 16 member 8
RGD ID: 13889341
Description: ENCODES a protein that exhibits monocarboxylic acid transmembrane transporter activity (inferred); INVOLVED IN monocarboxylic acid transport (inferred); transmembrane transport (inferred); ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); COVID-19 (ortholog); Emery-Dreifuss muscular dystrophy (ortholog); FOUND IN basal plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: monocarboxylate transporter 3; solute carrier family 16, member 8 (monocarboxylic acid transporter 3)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,800,397 - 9,806,543 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,799,830 - 9,806,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,201,563 - 7,206,416 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC16A8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,800,397 - 9,806,543 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,799,830 - 9,806,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,201,563 - 7,206,416 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC16A8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,078,137 - 38,084,184 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,078,134 - 38,084,184 (-)EnsemblGRCh38hg38GRCh38
GRCh372238,474,144 - 38,480,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,804,090 - 36,809,116 (-)NCBINCBI36Build 36hg18NCBI36
Build 342236,798,644 - 36,803,649NCBI
Celera2222,275,893 - 22,280,919 (-)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,438,822 - 21,443,842 (-)NCBIHuRef
CHM1_12238,432,878 - 38,437,904 (-)NCBICHM1_1
T2T-CHM13v2.02238,539,760 - 38,545,772 (-)NCBIT2T-CHM13v2.0
Slc16a8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,135,216 - 79,139,619 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,135,214 - 79,138,961 (-)EnsemblGRCm39 Ensembl
GRCm381579,251,016 - 79,255,562 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,251,014 - 79,254,761 (-)EnsemblGRCm38mm10GRCm38
MGSCv371579,081,446 - 79,085,178 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,078,271 - 79,082,003 (-)NCBIMGSCv36mm8
Celera1581,370,781 - 81,374,517 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Slc16a8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,698,701 - 112,702,496 (-)NCBIGRCr8
mRatBN7.27110,818,274 - 110,822,069 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,818,274 - 110,822,069 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,566,396 - 112,570,216 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,789,932 - 114,793,752 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,759,292 - 114,763,112 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,486,266 - 120,490,192 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,486,266 - 120,490,061 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,479,912 - 120,483,773 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,234,094 - 117,237,887 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,268,373 - 117,272,117 (-)NCBI
Celera7107,151,849 - 107,155,644 (-)NCBICelera
Cytogenetic Map7q34NCBI
Slc16a8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,400,826 - 24,405,208 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541324,400,621 - 24,406,754 (-)NCBIChiLan1.0ChiLan1.0
SLC16A8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,934,793 - 47,939,356 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,623,157 - 50,627,720 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,991,316 - 18,996,071 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,816,866 - 36,821,606 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,817,117 - 36,821,606 (-)Ensemblpanpan1.1panPan2
SLC16A8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,589,236 - 26,593,703 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,589,236 - 26,593,483 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,544,528 - 26,549,024 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,381,048 - 27,385,522 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,381,063 - 27,385,300 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,101,043 - 27,105,540 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,412,641 - 27,417,102 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,589,693 - 27,594,193 (+)NCBIUU_Cfam_GSD_1.0
Slc16a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,080,039 - 10,086,048 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,092,113 - 3,096,269 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,090,624 - 3,096,462 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC16A8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,780,596 - 20,785,845 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1920,780,848 - 20,785,655 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045104,984,913 - 104,990,189 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc16a8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247529,874,740 - 9,878,909 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247529,874,740 - 9,879,280 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC16A8
258 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system musculoskeletal system nervous system renal system
High
Medium
Low
Below cutoff 4 1 1 7 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000042449   ⟹   ENSSSCP00000045262
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl59,800,397 - 9,806,543 (+)Ensembl
RefSeq Acc Id: XM_021091500   ⟹   XP_020947159
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.159,799,830 - 9,806,550 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020947159 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000045262
  ENSSSCP00000045262.1
  ENSSSCP00025038197.1
  ENSSSCP00035005037.1
  ENSSSCP00045000031.1
  ENSSSCP00055025158.1
  ENSSSCP00065017796.1
Reference Protein Sequences
RefSeq Acc Id: XP_020947159   ⟸   XM_021091500
- UniProtKB: A0A287AMY7 (UniProtKB/TrEMBL),   A0A8D1YGS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000045262   ⟸   ENSSSCT00000042449
Protein Domains
Major facilitator superfamily (MFS) profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000113 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025063949 UniProtKB/TrEMBL
  ENSSSCG00035011759 UniProtKB/TrEMBL
  ENSSSCG00045000085 UniProtKB/TrEMBL
  ENSSSCG00055016032 UniProtKB/TrEMBL
  ENSSSCG00065031036 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000042449 ENTREZGENE
  ENSSSCT00000042449.3 UniProtKB/TrEMBL
  ENSSSCT00025087620.1 UniProtKB/TrEMBL
  ENSSSCT00035014770.1 UniProtKB/TrEMBL
  ENSSSCT00045000104.1 UniProtKB/TrEMBL
  ENSSSCT00055031610.1 UniProtKB/TrEMBL
  ENSSSCT00065041967.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MCT UniProtKB/TrEMBL
  MFS UniProtKB/TrEMBL
  MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
NCBI Gene SLC16A8 ENTREZGENE
PANTHER MONOCARBOXYLATE TRANSPORTER UniProtKB/TrEMBL
  PTHR11360:SF26 UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0A287AMY7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1YGS8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92948 ENTREZGENE