SLC6A20 (solute carrier family 6 member 20) - Rat Genome Database

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Gene: SLC6A20 (solute carrier family 6 member 20) Sus scrofa
Analyze
Symbol: SLC6A20
Name: solute carrier family 6 member 20
RGD ID: 13885616
Description: ENCODES a protein that exhibits amino-acid betaine transmembrane transporter activity (ortholog); INVOLVED IN amino acid import across plasma membrane (ortholog); amino-acid betaine transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH Glycinuria with or without Oxalate Urolithiasis (ortholog); iminoglycinuria (ortholog); intellectual disability (ortholog); FOUND IN brush border membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium- and chloride-dependent transporter XTRP3; solute carrier family 6 (proline IMINO transporter), member 20
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1328,899,821 - 28,945,187 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11328,897,831 - 28,945,191 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,015,969 - 32,043,611 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC6A20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1328,899,821 - 28,945,187 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11328,897,831 - 28,945,191 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,015,969 - 32,043,611 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC6A20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38345,755,449 - 45,796,536 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl345,755,449 - 45,796,574 (-)EnsemblGRCh38hg38GRCh38
GRCh37345,796,941 - 45,838,028 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36345,771,946 - 45,812,966 (-)NCBINCBI36Build 36hg18NCBI36
Celera345,734,543 - 45,775,644 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef345,840,974 - 45,881,992 (-)NCBIHuRef
CHM1_1345,746,576 - 45,787,673 (-)NCBICHM1_1
T2T-CHM13v2.0345,771,093 - 45,812,175 (-)NCBIT2T-CHM13v2.0
Slc6a20b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399123,422,888 - 123,461,603 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9123,419,865 - 123,461,630 (-)EnsemblGRCm39 Ensembl
GRCm389123,593,823 - 123,632,538 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9123,590,800 - 123,632,565 (-)EnsemblGRCm38mm10GRCm38
MGSCv379123,502,938 - 123,541,683 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369123,443,524 - 123,481,174 (-)NCBIMGSCv36mm8
Celera9124,048,718 - 124,087,483 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map974.19NCBI
Slc6a20a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88132,159,768 - 132,200,016 (-)NCBIGRCr8
mRatBN7.28123,282,325 - 123,322,609 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8123,281,472 - 123,322,573 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8128,872,218 - 128,912,417 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08127,071,181 - 127,111,393 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08124,900,709 - 124,940,903 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08132,713,013 - 132,753,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8132,665,927 - 132,753,292 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08131,865,713 - 131,905,845 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48128,412,080 - 128,452,212 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18128,431,816 - 128,471,949 (-)NCBI
Celera8122,390,559 - 122,430,719 (-)NCBICelera
Cytogenetic Map8q32NCBI
SLC6A20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2245,721,021 - 45,760,714 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1345,725,790 - 45,765,483 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0345,663,830 - 45,703,576 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1346,770,067 - 46,811,158 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl346,770,067 - 46,811,158 (-)Ensemblpanpan1.1panPan2
SLC6A20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,702,368 - 42,725,804 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2042,702,379 - 42,724,658 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2042,604,583 - 42,642,873 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02043,172,646 - 43,210,926 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2043,172,634 - 43,210,151 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12042,412,873 - 42,451,212 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,820,410 - 42,858,724 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02043,095,423 - 43,133,672 (+)NCBIUU_Cfam_GSD_1.0
Slc6a20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118197,794,009 - 197,842,662 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936695146,421 - 195,121 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936695146,571 - 193,428 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC6A20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1227,228,039 - 7,265,441 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl227,228,517 - 7,265,031 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041159,900,571 - 159,938,890 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc6a20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473075,084,748 - 75,109,112 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473075,081,189 - 75,107,288 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC6A20
1100 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000030079   ⟹   ENSSSCP00000019565
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1328,900,793 - 28,944,998 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000030240   ⟹   ENSSSCP00000019901
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1328,899,797 - 28,945,042 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000073228   ⟹   ENSSSCP00000070446
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1328,902,828 - 28,945,187 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000080455   ⟹   ENSSSCP00000062927
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1328,899,821 - 28,945,067 (-)Ensembl
RefSeq Acc Id: XM_003358406   ⟹   XP_003358454
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11328,897,831 - 28,945,110 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068639   ⟹   XP_020924298
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11328,897,831 - 28,945,191 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068640   ⟹   XP_020924299
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11328,897,831 - 28,939,819 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020924298   ⟸   XM_021068639
- Peptide Label: isoform X1
- UniProtKB: A0A5K1V2Y0 (UniProtKB/TrEMBL),   A0A4X1TCT1 (UniProtKB/TrEMBL),   A0A4X1TB29 (UniProtKB/TrEMBL),   A0A5G2QXJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003358454   ⟸   XM_003358406
- Peptide Label: isoform X2
- UniProtKB: A0A480MZK4 (UniProtKB/TrEMBL),   A0A8D1Y475 (UniProtKB/TrEMBL),   A0A8D1VG31 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020924299   ⟸   XM_021068640
- Peptide Label: isoform X3
- UniProtKB: A0A4X1TB35 (UniProtKB/TrEMBL),   A0A8D1Y3K4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000019565   ⟸   ENSSSCT00000030079
Ensembl Acc Id: ENSSSCP00000019901   ⟸   ENSSSCT00000030240
Ensembl Acc Id: ENSSSCP00000062927   ⟸   ENSSSCT00000080455
Ensembl Acc Id: ENSSSCP00000070446   ⟸   ENSSSCT00000073228


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000028643 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025049569 UniProtKB/TrEMBL
  ENSSSCG00030071440 UniProtKB/TrEMBL
  ENSSSCG00050061197 UniProtKB/TrEMBL
  ENSSSCG00055012783 UniProtKB/TrEMBL
  ENSSSCG00060042183 UniProtKB/TrEMBL
  ENSSSCG00065027038 UniProtKB/TrEMBL
  ENSSSCG00070007833 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000073228 ENTREZGENE
  ENSSSCT00000073228.2 UniProtKB/TrEMBL
  ENSSSCT00000080455 ENTREZGENE
  ENSSSCT00000080455.2 UniProtKB/TrEMBL
  ENSSSCT00025067525.1 UniProtKB/TrEMBL
  ENSSSCT00030100077.1 UniProtKB/TrEMBL
  ENSSSCT00050083408.1 UniProtKB/TrEMBL
  ENSSSCT00055025182.1 UniProtKB/TrEMBL
  ENSSSCT00055025251.1 UniProtKB/TrEMBL
  ENSSSCT00060057200.1 UniProtKB/TrEMBL
  ENSSSCT00065036412.1 UniProtKB/TrEMBL
  ENSSSCT00065036419.1 UniProtKB/TrEMBL
  ENSSSCT00070015168.1 UniProtKB/TrEMBL
  ENSSSCT00070015185.1 UniProtKB/TrEMBL
  ENSSSCT00070015196.1 UniProtKB/TrEMBL
  ENSSSCT00070015202.1 UniProtKB/TrEMBL
InterPro Na/ntran_symport UniProtKB/TrEMBL
  Neutral_aa_SLC6 UniProtKB/TrEMBL
  SNS_sf UniProtKB/TrEMBL
NCBI Gene SLC6A20 ENTREZGENE
PANTHER PTHR11616 UniProtKB/TrEMBL
  SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER XTRP3 UniProtKB/TrEMBL
Pfam SNF UniProtKB/TrEMBL
PRINTS NANEUSMPORT UniProtKB/TrEMBL
  ORPHTRNSPORT UniProtKB/TrEMBL
PROSITE NA_NEUROTRAN_SYMP_1 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_2 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF161070 UniProtKB/TrEMBL
UniProt A0A480MZK4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TB29 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TB35 ENTREZGENE
  A0A4X1TCT1 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TCU7_PIG UniProtKB/TrEMBL
  A0A5G2QXJ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2R003_PIG UniProtKB/TrEMBL
  A0A5K1V2Y0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1VG31 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Y3K4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Y475 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:93162 ENTREZGENE