SLC6A7 (solute carrier family 6 member 7) - Rat Genome Database

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Gene: SLC6A7 (solute carrier family 6 member 7) Sus scrofa
Analyze
Symbol: SLC6A7
Name: solute carrier family 6 member 7
RGD ID: 13882811
Description: ENCODES a protein that exhibits L-proline transmembrane transporter activity (ortholog); INVOLVED IN proline transmembrane transport (ortholog); proline transport (ortholog); ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN glutamatergic synapse (ortholog); presynaptic membrane (ortholog); Schaffer collateral - CA1 synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium-dependent proline transporter; solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2151,223,028 - 151,241,976 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12151,221,542 - 151,241,983 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22158,310,108 - 158,329,390 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC6A7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2151,223,028 - 151,241,976 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12151,221,542 - 151,241,983 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22158,310,108 - 158,329,390 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC6A7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385150,190,062 - 150,211,063 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5150,190,062 - 150,222,788 (+)EnsemblGRCh38hg38GRCh38
GRCh375149,569,625 - 149,590,626 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365149,549,713 - 149,570,828 (+)NCBINCBI36Build 36hg18NCBI36
Build 345149,549,712 - 149,570,827NCBI
Celera5145,650,900 - 145,672,027 (+)NCBICelera
Cytogenetic Map5q32ENTREZGENE
HuRef5144,717,577 - 144,738,751 (+)NCBIHuRef
CHM1_15149,002,105 - 149,023,228 (+)NCBICHM1_1
T2T-CHM13v2.05150,721,251 - 150,747,665 (+)NCBIT2T-CHM13v2.0
Slc6a7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391861,128,448 - 61,147,484 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1861,128,452 - 61,147,294 (-)EnsemblGRCm39 Ensembl
GRCm381860,995,376 - 61,014,416 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1860,995,380 - 61,014,222 (-)EnsemblGRCm38mm10GRCm38
MGSCv371861,155,034 - 61,173,853 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361861,120,749 - 61,139,568 (-)NCBIMGSCv36mm8
Celera1862,282,370 - 62,301,212 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1834.41NCBI
Slc6a7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81856,718,849 - 56,737,702 (-)NCBIGRCr8
mRatBN7.21854,448,464 - 54,467,319 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1854,448,464 - 54,467,319 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1856,536,530 - 56,555,331 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01857,251,136 - 57,269,935 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01855,072,309 - 55,091,168 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01856,305,765 - 56,325,179 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1856,305,735 - 56,331,991 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01855,539,473 - 55,557,682 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01855,557,703 - 55,564,493 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41856,958,965 - 56,977,159 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11857,031,196 - 57,049,391 (-)NCBI
Celera1852,602,558 - 52,620,980 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
Slc6a7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554154,314,067 - 4,332,665 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554154,314,090 - 4,332,659 (-)NCBIChiLan1.0ChiLan1.0
SLC6A7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24145,418,619 - 145,439,644 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15143,558,179 - 143,579,193 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05145,614,286 - 145,635,345 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15151,619,466 - 151,640,609 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5151,619,288 - 151,652,149 (+)Ensemblpanpan1.1panPan2
SLC6A7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1458,873,547 - 58,892,357 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl458,874,137 - 58,887,129 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha458,638,808 - 58,658,424 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0459,353,446 - 59,373,028 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl459,353,457 - 59,373,409 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1459,142,170 - 59,161,799 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0459,256,627 - 59,276,264 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0459,787,700 - 59,807,346 (-)NCBIUU_Cfam_GSD_1.0
Slc6a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213143,135,063 - 143,156,683 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365044,709,583 - 4,730,219 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365044,709,539 - 4,730,583 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC6A7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12352,799,847 - 52,820,745 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2352,800,358 - 52,820,732 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603424,896,351 - 24,917,248 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc6a7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247749,499,450 - 9,519,583 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247749,499,697 - 9,519,522 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC6A7
404 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 1 19 2 1 2 19 1 1

Sequence


Ensembl Acc Id: ENSSSCT00000015794   ⟹   ENSSSCP00000015378
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2151,223,028 - 151,241,976 (+)Ensembl
RefSeq Acc Id: XM_003124097   ⟹   XP_003124145
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,221,542 - 151,241,983 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003124145   ⟸   XM_003124097
- UniProtKB: A0A480NQW3 (UniProtKB/TrEMBL),   A0A8D1JWC6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000015378   ⟸   ENSSSCT00000015794


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014447 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025066642 UniProtKB/TrEMBL
  ENSSSCG00030025362 UniProtKB/TrEMBL
  ENSSSCG00035030278 UniProtKB/TrEMBL
  ENSSSCG00045027023 UniProtKB/TrEMBL
  ENSSSCG00050007065 UniProtKB/TrEMBL
  ENSSSCG00055007829 UniProtKB/TrEMBL
  ENSSSCG00060063932 UniProtKB/TrEMBL
  ENSSSCG00065037505 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015794 ENTREZGENE
  ENSSSCT00000015794.5 UniProtKB/TrEMBL
  ENSSSCT00025091527.1 UniProtKB/TrEMBL
  ENSSSCT00030035396.1 UniProtKB/TrEMBL
  ENSSSCT00035040118.1 UniProtKB/TrEMBL
  ENSSSCT00045046027.1 UniProtKB/TrEMBL
  ENSSSCT00050009648.1 UniProtKB/TrEMBL
  ENSSSCT00055015315.1 UniProtKB/TrEMBL
  ENSSSCT00060087253.1 UniProtKB/TrEMBL
  ENSSSCT00065051217.1 UniProtKB/TrEMBL
InterPro Na/ntran_symport UniProtKB/TrEMBL
  SNS_sf UniProtKB/TrEMBL
KEGG Report ssc:100516251 UniProtKB/TrEMBL
NCBI Gene SLC6A7 ENTREZGENE
PANTHER PTHR11616 UniProtKB/TrEMBL
  SODIUM-DEPENDENT PROLINE TRANSPORTER UniProtKB/TrEMBL
Pfam SNF UniProtKB/TrEMBL
PRINTS NANEUSMPORT UniProtKB/TrEMBL
PROSITE NA_NEUROTRAN_SYMP_1 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF161070 UniProtKB/TrEMBL
UniProt A0A480NQW3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1JWC6 ENTREZGENE, UniProtKB/TrEMBL
  F1RL70_PIG UniProtKB/TrEMBL
VGNC ID VGNC:93167 ENTREZGENE