LMNTD2 (lamin tail domain containing 2) - Rat Genome Database

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Gene: LMNTD2 (lamin tail domain containing 2) Sus scrofa
Analyze
Symbol: LMNTD2
Name: lamin tail domain containing 2
RGD ID: 13882171
Description: ENCODES a protein that exhibits structural constituent of chromatin (inferred); INVOLVED IN positive regulation of mRNA splicing, via spliceosome (ortholog); ASSOCIATED WITH Chanarin-Dorfman syndrome (ortholog); delta beta-thalassemia (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN lamin filament (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C2H11orf35; lamin tail domain-containing protein 2; uncharacterized protein C11orf35 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2323,647 - 329,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12323,642 - 329,782 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22344,764 - 350,776 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
lamin filament  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LMNTD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2323,647 - 329,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12323,642 - 329,782 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22344,764 - 350,776 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LMNTD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811554,850 - 560,738 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11554,850 - 560,738 (-)EnsemblGRCh38hg38GRCh38
GRCh3711554,850 - 560,738 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611544,857 - 550,779 (-)NCBINCBI36Build 36hg18NCBI36
Celera11617,191 - 623,436 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11369,534 - 375,805 (-)NCBIHuRef
CHM1_111553,624 - 559,707 (-)NCBICHM1_1
T2T-CHM13v2.011601,835 - 607,742 (-)NCBIT2T-CHM13v2.0
Lmntd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,789,903 - 140,795,617 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7140,789,905 - 140,793,993 (-)EnsemblGRCm39 Ensembl
GRCm387141,209,990 - 141,215,517 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,209,992 - 141,214,080 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,395,942 - 148,399,979 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367148,395,942 - 148,404,610 (-)NCBIMGSCv36mm8
Celera7141,003,808 - 141,007,845 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.5NCBI
Lmntd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81205,744,694 - 205,750,460 (-)NCBIGRCr8
mRatBN7.21196,315,112 - 196,320,880 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,315,115 - 196,319,156 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1204,660,610 - 204,664,654 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,787,283 - 211,791,316 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01204,461,417 - 204,465,450 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01214,197,126 - 214,202,828 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,196,430 - 214,202,853 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,114,665 - 221,120,278 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,404,427 - 201,408,471 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11201,555,509 - 201,559,470 (-)NCBI
Celera1193,948,986 - 193,953,030 (-)NCBICelera
Cytogenetic Map1q41NCBI
Lmntd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,489,481 - 11,493,923 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,487,918 - 11,493,281 (+)NCBIChiLan1.0ChiLan1.0
LMNTD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v292,932,147 - 2,936,845 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,149,330 - 2,153,981 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011559,779 - 564,584 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111588,693 - 594,851 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11588,816 - 594,794 (-)Ensemblpanpan1.1panPan2
LMNTD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11825,663,814 - 25,669,420 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1825,663,814 - 25,668,768 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1825,311,501 - 25,317,274 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01826,246,817 - 26,252,593 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1826,246,819 - 26,251,772 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11825,756,570 - 25,762,339 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01825,401,574 - 25,407,343 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01826,013,736 - 26,019,510 (-)NCBIUU_Cfam_GSD_1.0
Lmntd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947397,581 - 404,007 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936888396,629 - 403,614 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936888397,581 - 403,551 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LMNTD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11370,216 - 374,411 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1370,338 - 374,345 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,429,627 - 97,433,894 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lmntd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476621,891,281 - 21,896,450 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LMNTD2
84 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium
Low 2 1
Below cutoff 7 1 3 2 4 2 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000054138   ⟹   ENSSSCP00000057271
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2323,771 - 329,660 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000100562   ⟹   ENSSSCP00000079525
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2323,647 - 327,877 (-)Ensembl
RefSeq Acc Id: XM_021082545   ⟹   XP_020938204
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12323,642 - 329,782 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021082546   ⟹   XP_020938205
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12323,642 - 329,782 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021082547   ⟹   XP_020938206
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12323,642 - 329,782 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021082549   ⟹   XP_020938208
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12323,642 - 329,782 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020938204 (Get FASTA)   NCBI Sequence Viewer  
  XP_020938205 (Get FASTA)   NCBI Sequence Viewer  
  XP_020938206 (Get FASTA)   NCBI Sequence Viewer  
  XP_020938208 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000057271.3
  ENSSSCP00000079525.1
Reference Protein Sequences
RefSeq Acc Id: XP_020938206   ⟸   XM_021082547
- Peptide Label: isoform X3
- UniProtKB: A0A480DGH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020938208   ⟸   XM_021082549
- Peptide Label: isoform X4
- UniProtKB: A0A480DGH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020938205   ⟸   XM_021082546
- Peptide Label: isoform X2
- UniProtKB: A0A480DGH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020938204   ⟸   XM_021082545
- Peptide Label: isoform X1
- UniProtKB: A0A480DGH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000057271   ⟸   ENSSSCT00000054138
RefSeq Acc Id: ENSSSCP00000079525   ⟸   ENSSSCT00000100562
Protein Domains
LTD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000030137 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000054138.3 UniProtKB/TrEMBL
  ENSSSCT00000100562.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1260 UniProtKB/TrEMBL
InterPro Lamin_tail_dom UniProtKB/TrEMBL
  Lamin_tail_dom_sf UniProtKB/TrEMBL
NCBI Gene LMNTD2 ENTREZGENE
PANTHER LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam LTD UniProtKB/TrEMBL
PROSITE LTD UniProtKB/TrEMBL
Superfamily-SCOP SSF74853 UniProtKB/TrEMBL
UniProt A0A287BM73_PIG UniProtKB/TrEMBL
  A0A480DGH8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FJ85_PIG UniProtKB/TrEMBL
VGNC ID VGNC:89763 ENTREZGENE