USP51 (ubiquitin specific peptidase 51) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: USP51 (ubiquitin specific peptidase 51) Sus scrofa
Analyze
Symbol: USP51
Name: ubiquitin specific peptidase 51
RGD ID: 13878791
Description: ENCODES a protein that exhibits chromatin binding (inferred); cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN DNA damage response (inferred); DNA repair-dependent chromatin remodeling (inferred); proteolysis (inferred); ASSOCIATED WITH autistic disorder (ortholog); Dwarfism (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 51
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX48,048,223 - 48,050,355 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X48,047,658 - 48,051,941 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X54,046,247 - 54,050,090 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
USP51
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX48,048,223 - 48,050,355 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X48,047,658 - 48,051,941 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X54,046,247 - 54,050,090 (+)NCBISscrofa10.2Sscrofa10.2susScr3
USP51
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X55,484,616 - 55,489,848 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX55,484,616 - 55,489,848 (-)EnsemblGRCh38hg38GRCh38
GRCh37X55,511,049 - 55,516,281 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X55,529,687 - 55,532,356 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX59,350,733 - 59,355,315 (-)NCBICelera
Cytogenetic MapXp11.21NCBI
HuRefX52,562,965 - 52,563,571 (-)NCBIHuRef
CHM1_1X55,501,196 - 55,505,789 (-)NCBICHM1_1
T2T-CHM13v2.0X54,776,519 - 54,781,751 (+)NCBIT2T-CHM13v2.0
Usp51
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X151,789,433 - 151,794,360 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX151,789,465 - 151,792,412 (+)EnsemblGRCm39 Ensembl
GRCm38X153,006,469 - 153,011,364 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX153,006,469 - 153,009,416 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X149,441,012 - 149,444,004 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X148,349,229 - 148,350,113 (+)NCBIMGSCv36mm8
CeleraX136,241,129 - 136,244,306 (-)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Usp51
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X21,750,630 - 21,757,163 (-)NCBIGRCr8
mRatBN7.2X18,374,940 - 18,381,472 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX18,376,930 - 18,379,888 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX15,779,131 - 15,782,177 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X24,342,778 - 24,345,824 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X18,838,203 - 18,841,250 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X19,268,352 - 19,273,753 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX19,270,181 - 19,273,139 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X20,034,328 - 20,039,458 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X38,541,807 - 38,544,854 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX18,650,454 - 18,653,501 (-)NCBICelera
Cytogenetic MapXq12NCBI
USP51
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X56,913,201 - 56,918,775 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X56,916,807 - 56,922,382 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X47,747,547 - 47,753,119 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
USP51
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X47,055,226 - 47,059,552 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX38,292,359 - 38,295,093 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X47,362,810 - 47,365,543 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X46,666,562 - 46,669,293 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X47,287,285 - 47,289,981 (+)NCBIUNSW_CanFamBas_1.0
Usp51
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X39,915,334 - 39,919,137 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368191,116,447 - 1,118,558 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368191,115,524 - 1,119,083 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103232044
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X51,539,955 - 51,545,552 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX51,542,091 - 51,544,223 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236667123,047 - 8,957 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in USP51
51 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system
High
Medium 1
Low 1 3 18
Below cutoff 4 2 4 5 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000013504   ⟹   ENSSSCP00000013143
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX48,048,223 - 48,050,355 (-)Ensembl
RefSeq Acc Id: XM_003135110   ⟹   XP_003135158
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X48,047,658 - 48,051,941 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003135158   ⟸   XM_003135110
- UniProtKB: F1RTR5 (UniProtKB/TrEMBL),   A0A4X1VGU6 (UniProtKB/TrEMBL),   A0A8D1RED1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000013143   ⟸   ENSSSCT00000013504
Protein Domains
UBP-type   USP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012349 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015067613 UniProtKB/TrEMBL
  ENSSSCG00025056453 UniProtKB/TrEMBL
  ENSSSCG00030062819 UniProtKB/TrEMBL
  ENSSSCG00035033782 UniProtKB/TrEMBL
  ENSSSCG00040024865 UniProtKB/TrEMBL
  ENSSSCG00045022836 UniProtKB/TrEMBL
  ENSSSCG00050023034 UniProtKB/TrEMBL
  ENSSSCG00055020608 UniProtKB/TrEMBL
  ENSSSCG00060064732 UniProtKB/TrEMBL
  ENSSSCG00065053780 UniProtKB/TrEMBL
  ENSSSCG00070024332 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000013504 ENTREZGENE
  ENSSSCT00000013504.2 UniProtKB/TrEMBL
  ENSSSCT00015090560.1 UniProtKB/TrEMBL
  ENSSSCT00025077189.1 UniProtKB/TrEMBL
  ENSSSCT00030087876.1 UniProtKB/TrEMBL
  ENSSSCT00035044765.1 UniProtKB/TrEMBL
  ENSSSCT00040033194.1 UniProtKB/TrEMBL
  ENSSSCT00045038940.1 UniProtKB/TrEMBL
  ENSSSCT00050031088.1 UniProtKB/TrEMBL
  ENSSSCT00055040380.1 UniProtKB/TrEMBL
  ENSSSCT00060088345.1 UniProtKB/TrEMBL
  ENSSSCT00065073648.1 UniProtKB/TrEMBL
  ENSSSCT00070048580.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain_like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
KEGG Report ssc:100519179 UniProtKB/TrEMBL
NCBI Gene USP51 ENTREZGENE
PANTHER PTHR21646:SF38 UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A4X1VGU6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RED1 ENTREZGENE, UniProtKB/TrEMBL
  F1RTR5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:94774 ENTREZGENE